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1.
Otol Neurotol ; 42(4): 606-613, 2021 04 01.
Artículo en Inglés | MEDLINE | ID: mdl-33156238

RESUMEN

BACKGROUND: During the Covid-19 pandemic, otolaryngologists are at risk due to aerosol-generating procedures such as mastoidectomy and need enhanced personal protective equipment (PPE). Eye protection can interfere with the use of a microscope due to a reduction in the field of vision. We aimed to study the effect of PPE on the microsurgical field. METHODS: Five surgeons measured the visual field using digital calipers at different power settings. They were done with no PPE, a surgical mask, FFP3 mask (N99), and with the addition of small goggles, large vistamax goggles, vistamax plus a face shield, and only a face shield. The measurements were repeated with rings of 5 mm increments. We also measured the "eye relief" of the microscope which is the ideal distance for maximum field of view. RESULTS: There was no major reduction of the field with the surgical or FFP3 mask. But even simple goggles reduced the field up to 31.6% and there were progressive reductions of up to 75.7% with large goggles, 76.8% when a face shield was added, and 61.9% when only face shield was used. The distance rings more than 5 mm also affected the field of view.The eye relief of our eyepiece was found to be 15 mm. CONCLUSION: The current PPE eye protection is not compatible with the use of a microscope. There is scope for research into better eye protection. Mitigation strategies including barrier drapes and alternative techniques such as endoscopic surgery or use of exoscopes should also be considered.


Asunto(s)
COVID-19/prevención & control , Microcirugia , Otorrinolaringólogos , Equipo de Protección Personal/efectos adversos , Campos Visuales , COVID-19/transmisión , Humanos , Mastoidectomía/efectos adversos , Microcirugia/instrumentación , Microcirugia/métodos , SARS-CoV-2
2.
Otolaryngol Head Neck Surg ; 140(4): 498-504, 2009 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-19328337

RESUMEN

OBJECTIVE: Centrosome amplification as detected by gamma tubulin (GT) immunostaining is associated with genetic instability and tumor aggressiveness. We assessed GT for its ability to predict recurrence of squamous cell carcinoma of the larynx (SCCL). STUDY DESIGN: Case series with chart review. MATERIALS AND METHODS: Five micron sections of 35 archival SCCL samples were subjected to antigen retrieval and immunostaining with antibody to GT. The keratin antibody CK5 served as a positive control for antigen retrieval, and tonsillar tissue was used as a negative control. RESULTS: Of the 35 tumors analyzed, 22 were associated with recurrence(R) and 13 were not (NR). Fourteen of the 22 R tumors, but 0 of 13 of the NR tumours had a GT staining score of 2+ or 3+ (P < 0.0002). GT was also related to recurrence in node-negative tumors (P < 0.006) but was unrelated to T stage (P = 0.726). CONCLUSIONS: GT staining appears to be a better predictor of tumor recurrence than T stage and also predicts recurrence in N0 tumors.


Asunto(s)
Carcinoma de Células Escamosas/metabolismo , Carcinoma de Células Escamosas/patología , Neoplasias Laríngeas/metabolismo , Neoplasias Laríngeas/patología , Tubulina (Proteína)/metabolismo , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/terapia , Estudios de Cohortes , Terapia Combinada , Supervivencia sin Enfermedad , Femenino , Humanos , Neoplasias Laríngeas/terapia , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Valor Predictivo de las Pruebas , Estudios Retrospectivos
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