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Cell ; 175(5): 1185-1197.e22, 2018 11 15.
Artículo en Inglés | MEDLINE | ID: mdl-30415837

RESUMEN

We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least ∼9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central Andes by ∼4,200 years ago, while the other explains an affinity between the oldest North American genome associated with the Clovis culture and the oldest Central and South Americans from Chile, Brazil, and Belize. However, this was not the primary source for later South Americans, as the other ancient individuals derive from lineages without specific affinity to the Clovis-associated genome, suggesting a population replacement that began at least 9,000 years ago and was followed by substantial population continuity in multiple regions.


Asunto(s)
Genética de Población/historia , Genoma Humano , América Central , ADN Antiguo/análisis , ADN Mitocondrial/genética , Flujo Génico , Historia Antigua , Humanos , Modelos Teóricos , América del Sur
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