Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 9 de 9
Filtrar
Más filtros











Base de datos
Intervalo de año de publicación
1.
Rev Med Interne ; 39(12): 950-954, 2018 Dec.
Artículo en Francés | MEDLINE | ID: mdl-29914710

RESUMEN

INTRODUCTION: Bisalbuminemias consist in rare qualitative modifications of several aspects in the albumin pattern. Bisalbuminemias, most of which are not pathological, can be observed using capillary electrophoresis. CASE REPORTS: We report a case of hereditary bisalbuminemia diagnosed by chance while exploring chronic unexplained hypereosinophilia in a 42-year-old patient. The patient's normal lipid profile, the lack of an antibiotic treatment or pancreatic pathology, and the persistence of the bisalbuminemia after one month, suggested a diagnosis of genetic bisalbuminemia. In light of other such cases, we review the main causes of bisalbuminemia, both genetic and acquired. CONCLUSION: The diagnosis of genetic bisalbuminemia is made by first eliminating the usual acquired etiologies: analytical or drug interference, acute pancreatitis and binding of immunoglobulins. Then, after having checked the lipemic index, reviewed the patient's medical history, comorbidities, and treatments, repeating the electrophoresis will help identify the cause of the bisalbuminemia.


Asunto(s)
Albúminas/análisis , Antibacterianos/uso terapéutico , Artefactos , Electroforesis de las Proteínas Sanguíneas , Enfermedades Hematológicas/diagnóstico , Albúmina Sérica/análisis , Adulto , Albúminas/metabolismo , Diagnóstico Diferencial , Interacciones Farmacológicas , Femenino , Enfermedades Hematológicas/sangre , Humanos , Pancreatitis/sangre , Pancreatitis/tratamiento farmacológico
2.
Clin Biochem ; 51: 103-109, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28941591

RESUMEN

Immunoglobulin E (IgE) gammopathy is a rare disorder, accounting for just 0.1% of all patients with multiple myeloma (MM). Herein, we report a case of IgE monoclonal gammopathy without any biological and clinical symptoms, and we review 63 published cases in the literature. Demographic, biological and clinical presentations and features appear to be similar to those of other subtypes of MM, with a median age of diagnosis of 67years. There is a slight excess of male patients, and incidence seems to increase with age. The prevalence of renal failure, anaemia and hypercalcaemia at diagnosis was computed to be at 26%, 44% and 18%, respectively, in patients with MM. According to the literature, IgE MM is more aggressive and associated with poorer survival. Nonetheless, cases that are prolonged have also been described.


Asunto(s)
Inmunoglobulina E/sangre , Paraproteinemias/sangre , Adulto , Anciano , Anciano de 80 o más Años , Electroforesis Capilar , Femenino , Humanos , Masculino , Persona de Mediana Edad
4.
Ann Biol Clin (Paris) ; 67(3): 333-7, 2009.
Artículo en Francés | MEDLINE | ID: mdl-19411236

RESUMEN

We present a 27-year-old soldier exertional heat stroke case report. Clinical examination has been reassuring during hospitalization. However biological disorders, especially liver and haemostasis disturbances, show off exertional heat stroke is a serious pathology on which clinician and biologist attention must be focalized, even if evolution is the more often favourable when an adapted and rapid treatment is used.


Asunto(s)
Ejercicio Físico , Golpe de Calor/fisiopatología , Esfuerzo Físico/fisiología , Adulto , Alanina Transaminasa/sangre , Aspartato Aminotransferasas/sangre , Factores de Coagulación Sanguínea/metabolismo , Fibrinógeno/metabolismo , Golpe de Calor/sangre , Golpe de Calor/etiología , Humanos , Masculino
5.
Ann Biol Clin (Paris) ; 65(5): 577-80, 2007.
Artículo en Francés | MEDLINE | ID: mdl-17913680

RESUMEN

In biochemistry laboratory, monoclonal immunoglobulins are frequently found. They can lead to analytical interferences which are difficult to anticipate. In this case reports, a monoclonal immunoglobulin M with cryoglobulin effect has been responsible of false result of protein electrophoresis because of the whole precipitation of the monoclonal immunoglobulin. This case report allows us to remember the interferences caused by monoclonal immunoglobulins and that clinicians should be aware of these aspects of paraproteins and contacting the laboratory when encountering unexpected results.


Asunto(s)
Anticuerpos Monoclonales/análisis , Artefactos , Crioglobulinas/análisis , Inmunoglobulina M/análisis , Anciano de 80 o más Años , Diagnóstico Diferencial , Femenino , Humanos , Manejo de Especímenes , Macroglobulinemia de Waldenström/diagnóstico
6.
Ann Biol Clin (Paris) ; 63(1): 59-65, 2005.
Artículo en Francés | MEDLINE | ID: mdl-15689313

RESUMEN

Cryoglobulins are immunoglobulins or immune complexes which precipitate at a temperature lower than 37 degrees C and re-dissolve when rewarmed. So their collection and processing are critical. We describe the methodology used in the biochemical laboratory of Military hospital Laveran (Marseille) for detection determination of type and quantitation of cryoglobulins. In this study, we have found cryoglobulins in 53% of healthy subjects and in 77% of patients with chronic hepatitis C.


Asunto(s)
Crioglobulinas/análisis , Hepatitis C Crónica/sangre , Crioglobulinas/clasificación , Humanos , Inmunoglobulina G/sangre , Valores de Referencia , Albúmina Sérica/análisis
7.
Ann Biol Clin (Paris) ; 57(4): 474-80, 1999.
Artículo en Francés | MEDLINE | ID: mdl-10432372

RESUMEN

Cardio-vascular diseases are the most common cause of death in industrialized countries. A new marker has emerged among offending risk factors in the past few years: homocysteine. This sulphured amino-acid is an important intermediate in transsulphuration and remethylation reactions of methionine's metabolism. We proposed to evaluate a home made method of determination for this parameter by high performance liquid chromatography (HPLC) and to compare it to fluorescence polarization immunoassay technique (FPIA) and to gaz phase chromatography (CG-SM). This method associated with good sensibility and precision remain much less expensive than FPIA technique.


Asunto(s)
Enfermedades Cardiovasculares/diagnóstico , Homocisteína/sangre , Acetilcisteína/sangre , Biomarcadores/sangre , Enfermedades Cardiovasculares/sangre , Enfermedades Cardiovasculares/epidemiología , Cromatografía Líquida de Alta Presión/métodos , Cisteína/sangre , Dipéptidos/sangre , Técnica del Anticuerpo Fluorescente , Cromatografía de Gases y Espectrometría de Masas/métodos , Glutatión/sangre , Humanos , Reproducibilidad de los Resultados , Factores de Riesgo , Sensibilidad y Especificidad
9.
Sante Publique ; 10(1): 29-37, 1998 Mar.
Artículo en Francés | MEDLINE | ID: mdl-9685808

RESUMEN

The authors describe a collective histamine related food-poisoning epidemic that occurred in the Navy due to the consumption of imported smoked swordfish (Xyphias gladius). Twenty cases were detected. The relative risk among consumers of swordfish is at 7.44 (C.I. of 95%: 2.57-21.59) and the doses of histamine were from 2.030 to 4.750 ppm in 9 samples of tested fish (N < 200 ppm). The interest in using a high-resolution chromatographic liquid to ensure a diagnosis, and in using the community norms in force are shown. A recent review of the literature serves to show the variety of fish responsible for this type of accident, to insist on the mildness, elusiveness, variability, and lack of specificity of clinical signs and therefore risks error in diagnoses, treatment and under-reporting of this type of collective food-poisoning.


Asunto(s)
Brotes de Enfermedades , Peces , Conservación de Alimentos , Enfermedades Transmitidas por los Alimentos/etiología , Histamina/efectos adversos , Personal Militar , Animales , Cromatografía Líquida de Alta Presión , Brotes de Enfermedades/estadística & datos numéricos , Francia , Histamina/análisis , Humanos , Medicina Naval , Riesgo , Factores de Riesgo
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA