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1.
Khirurgiia (Mosk) ; (1): 5-14, 2021.
Artículo en Ruso | MEDLINE | ID: mdl-33395506

RESUMEN

OBJECTIVE: To analyze the long-term postoperative outcomes in patients with cicatricial tracheal stenosis and to determine the indications for various surgical strategies. MATERIAL AND METHODS: There were 976 patients with benign cicatricial tracheal stenosis for the period 2001-2017. Tracheal stenosis occurred after mechanical ventilation and tracheostomy in 910 (93.2%) patients. Other causes were neck trauma, burns, previous surgery or tuberculosis. Idiopathic stenosis was observed in 41 (4.2%) patients. Multiple-stage reconstructive treatment was possible due to benign nature of disease. There were 2.4 operations per a patient, and 976 patients underwent 2327 procedures. Circular tracheal resection was preferred (n=396). RESULTS: Surgical complications occurred in 107 (4.6%) cases, mortality rate - 0.3%. In long-term period, 42 patients died for various causes. In most cases (n=34, 80.9%), mortality was associated with concomitant diseases or consequences of trauma rather cicatricial tracheal stenosis or its treatment. Eight patients died from cicatricial tracheal stenosis or its treatment (7 patients after staged repair, 1 after circular tracheal resection). Four patients died due to asphyxia following T-tube obturation with a tracheobronchial secret or unjustified decannulation. For various reasons, 41 (6.2%) patients continued their treatment in other hospitals (4 patients died). Mortality rate in this group was 9.8%. Favorable long-term outcome was observed in 90.1% of patients, good and unsatisfactory results - in 7.2% and 1.8% of patients, respectively. Circular tracheal resection ensured better functional outcome. CONCLUSION: Surgical treatment of cicatricial tracheal stenosis is associated with low incidence of postoperative complications and mortality. However, further improvement in long-term results is associated with advanced rehabilitation programs for concomitant diseases. Treatment of cicatricial tracheal stenosis should be carried out at specialized hospitals.


Asunto(s)
Cicatriz/cirugía , Procedimientos de Cirugía Plástica , Estenosis Traqueal , Cicatriz/etiología , Constricción Patológica/etiología , Constricción Patológica/cirugía , Humanos , Procedimientos de Cirugía Plástica/métodos , Tráquea/cirugía , Estenosis Traqueal/diagnóstico , Estenosis Traqueal/etiología , Estenosis Traqueal/cirugía , Traqueostomía/efectos adversos , Resultado del Tratamiento
2.
Khirurgiia (Mosk) ; (5): 76-80, 2020.
Artículo en Ruso | MEDLINE | ID: mdl-32500693

RESUMEN

In this article is described a rare postoperative complication: epiphrenal diverticulum of the esophagus of the lower third of the esophagus in patient after antireflux surgery. Brief description of the main stages of surgical treatment. 96 patients with cardiofundal, subtotal or total hiatal hernias underwent operation. There were complications of I-II degree according to Clavien-Dindo in the early postoperative period in 11 patients (11.4%). Complications of IIIb degree were revealed in 2 patients (2.1%) in the early postoperative period and in 1 patient (1.0%) in the late postoperative period (2 months after hospitalization) - epiphrenal diverticulum of the esophagus. Laparotomy, the sagittal diafragmalnaya, diverticulectomy, valisesta pyloroplasty were performed. Postoperative period without complications. The patient's nutrition through the mouth is restored on the 5-th day. No dysphagia and reflux esophagitis were detected radiologically and endoscopically.


Asunto(s)
Divertículo Esofágico/etiología , Divertículo Esofágico/cirugía , Fundoplicación/efectos adversos , Hernia Hiatal/cirugía , Diafragma/cirugía , Humanos , Laparotomía , Píloro/cirugía
3.
Khirurgiia (Mosk) ; (1): 5-13, 2020.
Artículo en Ruso | MEDLINE | ID: mdl-31994494

RESUMEN

OBJECTIVE: To analyze the results of minimally invasive surgical procedures in patients with gastric GIST. MATERIAL AND METHODS: The study included 30 patients aged 52.2±9.8 years. ASA grade II (44%), III (26%) and I (23%) were predominant. Lesion of stomach body was noted in 17 (56%) patients, antrum - in 8 (27%), fundus - in 2 (7%) and cardia - in 3 (10%) patients. GIST was located on the anterior wall of stomach in 56% of patients. Exophytic growth was observed in 16 (53%) patients, endophytic - in 12 (40%), transmural growth - in 2 (7%) cases. T2 grade of tumor was noted in 67% of cases (TNM 8). All patients underwent laparoscopic or robot-assisted ('daVinci Si') partial resection of the stomach. RESULTS: Radical resection (R0) without injury of pseudocapsule of tumor was made in all patients. Laparoscopic procedures were performed in 25 (83%) patients, robot-assisted - in 5 (17%). Early postoperative complications (Clavien-Dindo II) were observed in 3 patients. Spindle cell structure of tumors (93%) with low mitotic activity (63%) prevailed. Tumor stage I was observed in 56% of patients. Patients with high mitotic tumor index (44%) were directed to targeted therapy. Recurrence and/or metastasis in long-term period were absent in 26 (87%) patients. CONCLUSION: Laparoscopic surgery for gastric GIST is safe and characterized by the absence of significant postoperative complications and long-term recurrence-free period. The use of robotic surgical system is effective and justified for anatomically difficult localization of GIST.


Asunto(s)
Gastrectomía/métodos , Tumores del Estroma Gastrointestinal/cirugía , Neoplasias Gástricas/cirugía , Adulto , Humanos , Laparoscopía , Persona de Mediana Edad , Procedimientos Quirúrgicos Robotizados
4.
Khirurgiia (Mosk) ; (6): 41-48, 2019.
Artículo en Ruso | MEDLINE | ID: mdl-31317940

RESUMEN

AIM: To analyze treatment of patients with reflux esophagitis and large hiatal hernia. MATERIAL AND METHODS: There were 85 patients with reflux esophagitis and large hiatal hernia. Laparoscopic repair was performed in 33 patients, laparotomy - in 52 cases. All patients underwent fundo- or gastroplication by A.F. Chernousov, correction of large defect of hiatal orifice by cruroraphy was applied in 55 (64.7%) patients. RESULTS: Postoperative morbidity was near 10% after laparoscopic and conventional surgery despite more difficult video-assisted endoscopic technique. Complications Clavien-Dindo grade I-II were noted in 4 (12.1%) patients after laparoscopic treatment and in 6 (11.5%) patients after laparotomy. Medication was effective in all cases. Two patients with subtotal hernias had complications Clavien-Dindo grade IIIB after endoscopic surgery: recurrent hiatal hernia followed by severe reflux esophagitis and dysphagia. These complications required redo surgery. Repair of hiatal orifice is always possible without mesh reinforcement. Posterior cruroraphy is feasible and effective in all patients. Incidence of intraoperative and postoperative complications is comparable in both approaches (p<0.05). Mean hospital-stay after laparotomy was 7.3 days, after laparoscopy - 5.8 days. CONCLUSION: Endoscopic formation of antireflux cuff by A.F. Chernousov is appropriate and effective in patients with reflux esophagitis and large/giant hiatal hernias.


Asunto(s)
Esofagitis Péptica/cirugía , Fundoplicación/métodos , Reflujo Gastroesofágico/cirugía , Hernia Hiatal/cirugía , Esofagitis Péptica/complicaciones , Fundoplicación/efectos adversos , Hernia Hiatal/clasificación , Hernia Hiatal/complicaciones , Humanos , Laparoscopía
6.
Khirurgiia (Mosk) ; (12): 17-27, 2017.
Artículo en Ruso | MEDLINE | ID: mdl-29286026

RESUMEN

AIM: To analyze quality of life of patients with complicated reflux-esophagitis followed antireflux surgery. MATERIAL AND METHODS: The trial enrolled 200 patients who underwent surgical treatment at the Burdenko Faculty Surgery Clinic of Sechenov First Moscow State Medical University for complicated reflux esophagitis from 2008 to 2015. Inclusion criteria were long-standing reflux esophagitis irresistible to conservative treatment, hiatal hernia with shortening of the esophagus and/or peptic stricture and/or Barrett's esophagus. Patients were divided into 2 groups according to the degree of esophagus shortening: group I - 98 patients with esophagus shortening degree I; group II - 102 patients with shortening grade II. Men/women ratio was 87(43.5%)/113(56.5%). Mean age was 56.0±13.9 years (16-83 years). We performed fundoplication in A.F. Chernousov modification in the first group and modified valvular gastroplication in the second group. All patients underwent survey within 6 months - 10 years after surgery to assess long-term outcomes. X-ray examination, upper GI endoscopy, standard laboratory tests were performed with pH-impedance and computed tomography if it was necessary. Quality of life was estimated by RAND SF-36 and GSRS (Gastrointestinal Symptom Rating Scale) questionnaires. RESULTS: SF-36 questionnaire revealed postoperative changes of physical, psychological and social values and was able to compare them with those in general population. Postoperative overall health was significantly higher in both groups compared with preoperative level and comparable with general population. GSRS questionnaire have also revealed positive changes. Overall postoperative GSRS score was 1.6±0.5 and 1.6±0.6 points in groups I and II respectively that corresponds to minor concern after surgery.


Asunto(s)
Esófago de Barrett/cirugía , Esofagitis Péptica/cirugía , Esofagoscopía , Fundoplicación , Reflujo Gastroesofágico/complicaciones , Hernia Hiatal/cirugía , Laparoscopía , Calidad de Vida , Adulto , Cuidados Posteriores/métodos , Anciano , Esófago de Barrett/etiología , Esófago de Barrett/psicología , Esofagitis Péptica/etiología , Esofagitis Péptica/psicología , Esofagoscopía/efectos adversos , Esofagoscopía/métodos , Femenino , Fundoplicación/efectos adversos , Fundoplicación/métodos , Hernia Hiatal/etiología , Hernia Hiatal/psicología , Humanos , Laparoscopía/efectos adversos , Laparoscopía/métodos , Masculino , Persona de Mediana Edad , Moscú , Evaluación de Resultado en la Atención de Salud , Periodo Posoperatorio , Encuestas y Cuestionarios
7.
Khirurgiia (Mosk) ; (10): 25-30, 2017.
Artículo en Ruso | MEDLINE | ID: mdl-29076479

RESUMEN

AIM: To analyze the first experience of laparoscopic and robot-assisted surgery for locally advanced and generalized stomach cancer at the Burdenko Clinic of Faculty Surgery. MATERIAL AND METHODS: Since 2011 27 laparoscopic and 2 robot-assisted operations for locally advanced and generalized stomach cancer have been performed in our hospital. Mean age of patients was 62.1±10 years. There were 19 men and 10 women. RESULTS: There were 11 gastrectomies with abdominal esophageal resection and 18 Billroth I subtotal resections. Advanced surgery was made in 4 (13.7%) patients including 1 case of transverse colon resection and 3 cases of liver resection. Mean time of surgery was 260 min (180-380 min) in gastrectomy, 210 min (175-310 min) in subtotal resection. Mean intraoperative blood loss was 120 ml (50-220 ml). CONCLUSION: Minimally invasive technologies reliably reduce blood loss, rehabilitation, ICU- and hospital-stay. The quality of life after minimally invasive interventions is significantly higher compared with conventional surgery while reduced rehabilitation allows to start chemotherapy already in early postoperative period.


Asunto(s)
Gastrectomía , Laparoscopía , Calidad de Vida , Procedimientos Quirúrgicos Robotizados , Neoplasias Gástricas , Adenocarcinoma/patología , Adenocarcinoma/cirugía , Anciano , Femenino , Gastrectomía/métodos , Gastrectomía/psicología , Humanos , Laparoscopía/efectos adversos , Laparoscopía/métodos , Masculino , Persona de Mediana Edad , Procedimientos Quirúrgicos Mínimamente Invasivos/efectos adversos , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Estadificación de Neoplasias , Evaluación de Procesos y Resultados en Atención de Salud , Estudios Retrospectivos , Procedimientos Quirúrgicos Robotizados/efectos adversos , Procedimientos Quirúrgicos Robotizados/métodos , Federación de Rusia , Neoplasias Gástricas/patología , Neoplasias Gástricas/cirugía
9.
Khirurgiia (Mosk) ; (7): 27-33, 2015.
Artículo en Ruso | MEDLINE | ID: mdl-26271561

RESUMEN

AIM: To study the effectiveness and impact of cryoprecipitate and alloplant on regeneration of liver tissue in patients with cirrhosis. MATERIAL AND METHODS: 114 patients with liver cirrhosis have been treated at the Department of Faculty Surgery of I.M. Sechenov First Moscow State Medical University from 2007 to 2014. Cryoprecipitate and alloplant were injected into cirrhotic liver tissue in the first (72 patients) and second (42 patients) groups under ultrasound control respectively. Patients' age was 48.9±12.14 years (range 18-75). There were 66 men (58%) and 48 (42%) women. Mixed (toxic and viral) etiology of cirrhosis was observed in 40.3% of patients, viral--in 25.8%, toxic--in 34.2%. RESULTS: Minimally invasive treatment under ultrasound showed significant (p>0.05) positive dynamics of hepatocellular failure, cytolytic and cholestatic syndromes, hypersplenism in 3, 6 and 12 months after cryoprecipitate administration in most patients with cirrhosis Child-Pugh class A, B and C (group 1). Alloplant injected into hepatic tissue causes less regeneration of liver tissue. It improves clinical and laboratory parameters in patients with cirrhosis Child-Pugh classes A and B. In case of class C allopolant is not effective.


Asunto(s)
Tratamiento Basado en Trasplante de Células y Tejidos/métodos , Factor VIII/farmacología , Fibrinógeno/farmacología , Cirrosis Hepática/terapia , Regeneración Hepática/fisiología , Adolescente , Adulto , Anciano , Aloinjertos , Femenino , Fibronectinas , Humanos , Cirrosis Hepática/patología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
13.
Khirurgiia (Mosk) ; (6): 13-20, 2014.
Artículo en Ruso | MEDLINE | ID: mdl-25042185

RESUMEN

Primary hyperparathyroidism is the most common disease in Russian Federation, cured by endocrine surgeons. Health status after surgical correction of primary hyperparathyroidism depends on availability of screening hypercalciemia, which is still absent in our country. Another problem is a model of surgical management of primary hyperparathyroidism (frozen section, intraoperative monitoring of parathyroid hormone, gamma-detection and so on). Although minimally invasive parathyroidectomy has become the only method of treatment in many countries, it is still crucial to identify and accurately localize parathyroid glands before bilateral neck exploration surgery. The diagnostic efficacy of the various imaging techniques is still the subject of current debate. The usefulness of preoperative parathyroid imaging with both dual scintigraphy-single-photon emission computed tomography (SPECT) Tc 99m and high-resolution ultrasonography (US) was studied in 92 patients undergoing operations for primary hyperparathyroidism. The accuracy of "integrated" ultrasonography ("check-up US", "target US" after SPECT) and "intraoperative US") of parathyroid glands was 92.9%, sensitivity - 91% and positive predictive value - 94%. This study supports an algorithm of obtaining "integrated" ultrasonography as the initial and in most cases the only preoperative localization tests for patients with primary hyperparathyroidism.


Asunto(s)
Hiperparatiroidismo Primario , Glándulas Paratiroides , Paratiroidectomía , Complicaciones Posoperatorias/prevención & control , Tomografía Computarizada de Emisión de Fotón Único/métodos , Ultrasonografía/métodos , Adulto , Anciano , Investigación sobre la Eficacia Comparativa , Femenino , Humanos , Hiperparatiroidismo Primario/diagnóstico , Hiperparatiroidismo Primario/cirugía , Masculino , Persona de Mediana Edad , Monitoreo Intraoperatorio/métodos , Moscú , Glándulas Paratiroides/diagnóstico por imagen , Paratiroidectomía/efectos adversos , Paratiroidectomía/métodos , Cuidados Preoperatorios/métodos , Reproducibilidad de los Resultados , Estudios Retrospectivos , Resultado del Tratamiento
14.
Khirurgiia (Mosk) ; (5): 28-36, 2014.
Artículo en Ruso | MEDLINE | ID: mdl-24874221

RESUMEN

It was analyzed the results of surgical treatment of 118 patients with stomach cancer. Lymphadenectomy and gastrectomy were done in all cases. All patients were divided into two groups. Gastrectomy and splenectomy were performed in the first group, gastrectomy with preservation of spleen was done in the second group. It was revealed that splenectomy is not an independent prognostic factor influencing on prolonged survival of patients with stomach cancer. Preservation of spleen permits to reduce the number of early postoperative complications.


Asunto(s)
Gastrectomía/métodos , Complicaciones Posoperatorias/prevención & control , Bazo , Esplenectomía , Neoplasias Gástricas , Adulto , Femenino , Humanos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Pronóstico , Bazo/patología , Bazo/cirugía , Esplenectomía/efectos adversos , Esplenectomía/métodos , Neoplasias Gástricas/clasificación , Neoplasias Gástricas/mortalidad , Neoplasias Gástricas/patología , Neoplasias Gástricas/cirugía , Análisis de Supervivencia , Resultado del Tratamiento
17.
Bull Exp Biol Med ; 154(3): 396-8, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23484209

RESUMEN

The stimulatory effect of cryoprecipitate on liver regeneration was studied in rabbits with cirrhosis of the liver induced by subcutaneous injection of tetrachloromethane. Cryoprecipitate stimulated the hepatocyte regeneration (appearance of binuclear and proliferating cells) in liver tissue in cirrhosis, but the initial structure of the liver was not restored. The newly formed focus of regeneration with proper girder structure of hepatocytes forced back the connective tissue. Highly concentrated solution of fibrinogen, injected by puncture method into cirrhotic hepatic tissue, stimulated its regeneration.


Asunto(s)
Factor VIII/administración & dosificación , Fibrinógeno/administración & dosificación , Cirrosis Hepática Experimental/tratamiento farmacológico , Regeneración Hepática/efectos de los fármacos , Animales , Tetracloruro de Carbono , Proliferación Celular , Hepatocitos/efectos de los fármacos , Hepatocitos/metabolismo , Hígado/efectos de los fármacos , Hígado/patología , Cirrosis Hepática Experimental/inducido químicamente , Cirrosis Hepática Experimental/metabolismo , Conejos
18.
Khirurgiia (Mosk) ; (7): 12-7, 2012.
Artículo en Ruso | MEDLINE | ID: mdl-22968498

RESUMEN

Results of surgical treatment of 65 patients with the combined hydatid disease were analyzed. Lung invasion was combind with liver cysts in 57 patients, spleen -- in 2 patients, soft tissues of the thorax - in 2 patients and retroperitoneal cysts were found in 3 patients. Lung echinococcectomy with the use of minithoracotomy proved to be a method of choice. The access permits early recovery and shorter rehabilitation period, allowing to perform the second liver surgery on the 3--7th day after the first operation.


Asunto(s)
Equinococosis Hepática , Equinococosis Pulmonar , Neumonectomía/métodos , Succión/métodos , Adulto , Equinococosis Hepática/complicaciones , Equinococosis Hepática/diagnóstico , Equinococosis Hepática/fisiopatología , Equinococosis Hepática/cirugía , Equinococosis Pulmonar/complicaciones , Equinococosis Pulmonar/diagnóstico , Equinococosis Pulmonar/fisiopatología , Equinococosis Pulmonar/cirugía , Femenino , Humanos , Tiempo de Internación , Hígado/diagnóstico por imagen , Hígado/cirugía , Pulmón/diagnóstico por imagen , Pulmón/cirugía , Masculino , Procedimientos Quirúrgicos Mínimamente Invasivos , Radiografía , Estudios Retrospectivos , Resultado del Tratamiento
19.
Khirurgiia (Mosk) ; (8): 39-43, 2012.
Artículo en Ruso | MEDLINE | ID: mdl-22968556

RESUMEN

The efficacy of the medicamentous prophylaxis of the acute postoperative pancreatitis (APP) was estimated in 594 patients. They all were divided into 3 groups: 1st was treated with octreotide, 2nd - with octreotide-depo, 3rd - with 5-ftoruracil and dalargin. Patients of the 3rd group showed the highest levels of α-amylase in both blood and drainage fluid during the early postoperative period. The frequency and severity of postoperative complication rates were the lowest in those patients, who received octreotide-depo and was 3,06%; whereas among patients of the 2nd group it was 16,8% and among those, who were treated with 5-ftoruracil and dalargin, it was 22,4%. The destructive forms of pancreatitis were registered in 2nd and 3rd groups in 1 and 3 patients, respectively. Intraabdominal abscesses were registered in 1 patient of the 1st and 6 patients of the 3rd group, respectively. The lethality rate was 0.9% in the 1st group; 1.02% in the 2nd and 1.8% in the 3rd group. The use of somatostatine analogues in the prophylaxis of postoperative complications proved to decrease overall complications' rate and, first of all, the rate of postoperative destructive pancreatitis. The use of the prolonged forms of somatostatine analogues, i.e., octreotide depo 10 mg is considered to be highly effective.


Asunto(s)
Gastrectomía/efectos adversos , Escisión del Ganglio Linfático/efectos adversos , Octreótido/administración & dosificación , Pancreatitis Aguda Necrotizante/prevención & control , Neoplasias Gástricas/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Relación Dosis-Respuesta a Droga , Femenino , Estudios de Seguimiento , Gastrectomía/métodos , Fármacos Gastrointestinales/administración & dosificación , Humanos , Infusiones Intravenosas , Escisión del Ganglio Linfático/métodos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Pancreatitis Aguda Necrotizante/diagnóstico , Pancreatitis Aguda Necrotizante/etiología , Estudios Retrospectivos , Neoplasias Gástricas/secundario , Factores de Tiempo , Resultado del Tratamiento
20.
Vestn Rentgenol Radiol ; (4): 37-41, 2011.
Artículo en Ruso | MEDLINE | ID: mdl-22288146

RESUMEN

In the period 2009 to 2010, diagnostic multislice spiral computed tomography (MSCT) was carried out in 49 patients with gastric cancer. The efficiency of dynamic MSCT in detecting a tumor and determining its locoregional extent was evaluated. The results of dynamic MSCT were compared with those of postoperative histological examination. The possibility of detecting gastric cancer by dynamic MSCT was ascertained to depend on the depth of tumor invasion and to average 29, 71, 72, and 77% for T1, T2, T3, and T4, respectively. Dynamic MSCT showed a correlation between the frequency of metastatic lesion and the sizes of lymph nodes (r = 0.54; p = 0.0001) and their number (r = 0.82; p < 0.0001).


Asunto(s)
Ganglios Linfáticos/diagnóstico por imagen , Tomografía Computarizada Multidetector/métodos , Invasividad Neoplásica/diagnóstico por imagen , Metástasis de la Neoplasia/diagnóstico por imagen , Estadificación de Neoplasias/métodos , Neoplasias Gástricas/diagnóstico por imagen , Estómago/diagnóstico por imagen , Anciano , Femenino , Humanos , Ganglios Linfáticos/patología , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Estómago/patología , Neoplasias Gástricas/patología
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