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Voen Med Zh ; 337(7): 25-33, 2016 07.
Artículo en Ruso | MEDLINE | ID: mdl-30590889

RESUMEN

On selection of external bleeding models for preclinical evaluation of the effectiveness of local haemostatic agents (literature review). To temporarily stop of external bleeding traditionally use a pressure bandage or tourniquet, but not for all types of wounds it is possible and appropriate to apply these dressings. In recent times there has been significant progress in the development and improvement of local haemostatic agents used for the first aid. There are currently conflicting information about their effectiveness, presented by various authors, requires standardization of experimental modelsforpre-clinical testing of medical devices in this class. Following a review of domestic and foreign literature DroDosed to standardize external bleeding model for assessing the effectiveness of local haemostatic agents.


Asunto(s)
Modelos Animales de Enfermedad , Hemorragia/tratamiento farmacológico , Técnicas Hemostáticas , Hemostáticos/uso terapéutico , Animales , Evaluación Preclínica de Medicamentos/métodos , Hemorragia/patología , Hemorragia/fisiopatología , Humanos
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