RESUMEN

Objective To analyze the first degree relatives of schizophrenia cognitive function damage degree and range, and make reasonable cognitive behavior intervention program. Methods Prospective selected 108 patients in Palit Provincial Hospital who were diagnosed with schizophrenia as the patient group, selected the same period first-degree relatives of patients with 108 cases as the kinship group, another 108 healthy volunteers were recruited to the normal group, compare and analyze the detection results of cognitive function of schizophrenia complete sets of test ing-consensus Version (MCCB) between the three groups and accordingly develope targeted cognitive interventions. Results Of all the 10 test of MCCB, the difference in verbal fluency between three groups was not significant (P>0.05),the remaining nine scores all had statistically significant difference(P<0.05)among three groups. There were sta-tistically significant differences(P<0.05) in all eight scores except continuous operational capability and verbal fluency between kin group and normal group,the differences in the spatial extent,symbol coding, maze,continuous operation ability were significant(P<0.05) between kin group and patients group. Conclusion First-degree relatives of patients with schizophrenia prevalence of cognitive impairment,cognitive behavior reasonable intervention can improve patients cognitive function level,improve the quality of life.