1.
Chem Asian J
; 19(9): e202400126, 2024 May 02.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38441246
RESUMEN
Palladium serves as a multi-functional catalyst which is controllable by tuning reaction conditions. This work demonstrated the utilization of a palladium catalyst for the synthesis of phenanthrenols by cascade palladium-catalyzed Suzuki/Heck reaction between chalcone and 2-bromophenylboronic acid, followed by Michael addition. The sequential reaction could be controlled by reactivity of the palladium catalyst in different solvents and concentrations of reagents. This protocol could be applied to a broad range of substrates to give products in low to good yields.