RESUMEN
Patients with hepatocellular carcinoma may manifest paraneoplastic syndromes such as hypercholesterolaemia, hypoglycaemia, hypercalcaemia and erythrocytosis. An exceptional case of hepatocellular carcinoma associated with polymyositis, a rheumatic paraneoplastic syndrome, is reported. A 72-year-old male complained for a recent muscular weakness mainly in the proximal limb muscles. The clinical course, a raised level of serum creatine kinase and electromyographic findings suggested polymyositis, and the pathological findings on muscle biopsy were compatible with this diagnosis. Computed tomography of the upper abdomen revealed a mass lesion in segment IV, V and VII of the liver, and alpha foetoprotein level was high, resulting in the diagnosis of hepatocellular carcinoma.
Asunto(s)
Carcinoma Hepatocelular/diagnóstico , Neoplasias Hepáticas/diagnóstico , Síndromes Paraneoplásicos/etiología , Polimiositis/etiología , Anciano , Carcinoma Hepatocelular/sangre , Carcinoma Hepatocelular/diagnóstico por imagen , Resultado Fatal , Humanos , Neoplasias Hepáticas/sangre , Neoplasias Hepáticas/diagnóstico por imagen , Masculino , Tomografía Computarizada por Rayos X , alfa-Fetoproteínas/análisisAsunto(s)
Ciprofloxacina/uso terapéutico , Infecciones por Clostridium/diagnóstico , Metronidazol/uso terapéutico , Ofloxacino/uso terapéutico , Osteomielitis/microbiología , Columna Vertebral/microbiología , Adulto , Antibacterianos/uso terapéutico , Clostridium/efectos de los fármacos , Quimioterapia Combinada , Humanos , Inmunocompetencia , Masculino , Resultado del TratamientoAsunto(s)
Absceso/diagnóstico , Enfermedades del Ano/diagnóstico , Fiebre , Ciática , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Vertebral hydatidosis (VH) is uncommon. It is the most frequent skeletal manifestation of echinococcosis. It is also the most serious one. We report a case of VH revealed by a kyphoscoliosis with dorsal pain and point out the contibution of new medical imagings in the diagnosis of VH and in the patient follow-up. We stress on the difficulties of the care management of this disease and its poor prognosis because of the risk of neurological damages and frequent recurrences.
Asunto(s)
Equinococosis/diagnóstico , Enfermedades de la Columna Vertebral/parasitología , Columna Vertebral , Adolescente , Equinococosis/diagnóstico por imagen , Humanos , Imagen por Resonancia Magnética , Masculino , Pronóstico , Radiografía , TúnezRESUMEN
UNLABELLED: Autoantibodies to ribosomal P proteins (anti-P) are directed against three ribosomal phosphoproteins (P0, P1, and P2) and are believed to be specific markers for systemic lupus erythematosus (SLE), particularly with neuropsychiatric manifestations. The objective of this study was to determine the rate of occurrence and clinical significance of anti-P in Tunisian patients. METHODS: We included 100 Tunisian patients with SLE whose sera were received between January 1998 and December 2000 by the immunology laboratory of the Charles Nicolle Teaching Hospital in Tunis, Tunisia, and were tested for anti-P. An immunodot technique based on a synthetic protein shared by all ribosomal phosphoproteins was used. RESULTS: Sera from 22 (22%) patients were positive for anti-P. This rate is consistent with the literature. We found no statistically significant associations between anti-P and specific manifestations of SLE. CONCLUSION. We found that anti-P were significantly associated with anti-Sm and anti-RNP, as reported previously. The significance of these associations remains debatable.
Asunto(s)
Autoanticuerpos/sangre , Enfermedades Autoinmunes/inmunología , Lupus Eritematoso Sistémico/inmunología , Proteínas Ribosómicas/inmunología , Adolescente , Adulto , Animales , Enfermedades Autoinmunes/epidemiología , Enfermedades Autoinmunes/etiología , Biomarcadores/sangre , Niño , Femenino , Humanos , Immunoblotting , Lupus Eritematoso Sistémico/complicaciones , Lupus Eritematoso Sistémico/epidemiología , Masculino , Persona de Mediana Edad , Ratas , Células Tumorales Cultivadas , Túnez/epidemiologíaRESUMEN
We report a case of 67-year-old woman with 11-year history of hemodialysis that complain of neck pain associated with cervico-brachial neuralgia. Imaging finding simulate infectious spondylitis. We consider the diagnosis of destructive spondylarthropathy in hemodialyzed patient since etiologic investigation was negative and RMN finding was suggestive. Our patient was partially improved with symptomatic treatment.
Asunto(s)
Vértebras Cervicales/patología , Diálisis Renal/efectos adversos , Espondiloartropatías/etiología , Anciano , Diagnóstico Diferencial , Femenino , Humanos , Espondiloartropatías/microbiología , Espondiloartropatías/patologíaRESUMEN
A 58 year old man suffered from low back pain. Physical examination showed asymmetry of the quadriceps and slight motor deficiency of right leg. Plain radiography of the pelvis revealed a large osteophyte, developed anteriorly at the low part of the right sacro iliac joint. CT exam of lumbar spin was normal. But, it confirmed osteophyte of right sacro iliac. Percutaneous injection of a small quantity of xylocaine under CT guidance in the site of the osteophyte behind crural muscle was marked by immediate disappearance of the pain, confirming the site of conflict between the crural nerve and the osteophyte. The patient was treated by injection of corticosteroid at the same location. Recovery was good.