RESUMEN
PURPOSE: The aim of the study was to evaluate patient tolerability and compliance to two bowel cleansing agents (PEG-ELS and NaP) as well as to compare the cost effectiveness. METHODS: Three hundred and forty-three consecutive patients were randomized to receive either the standard 4 1 of polyethylene glycol and electrolyte lavage solution (PEG-ELS) or 90 ml of sodium phosphate (NaP). All patients were advised to be on a clear liquid diet one day before starting the bowel cleansing regimen and to take ornidazole orally (3 x 2 tablets) 24 hours before surgery. Patient tolerabilty and compliance to the regimens were assessed based on complaints of nausea, vomiting and the need of antiemetics. In addition completion of the regimens was evaluated in both groups. RESULTS: The need for antiemetics because of nausea and vomiting was statistically higher in the PEG-ELS group than the NaP group (p = 0.000). Regimen completion rate was statistically higher in the NaP group than in the PEG-ELS group (p = 0.000). NaP is more cost effective than PEG-ELS. CONCLUSION: NaP was rated superior to PEG-ELS in terms of patient tolerability, compliance, completion of the regimen and cost effectiveness and should be the first-choice treatment.
Asunto(s)
Catárticos/efectos adversos , Electrólitos/efectos adversos , Neoplasias de los Genitales Femeninos/cirugía , Fosfatos/efectos adversos , Polietilenglicoles/efectos adversos , Cuidados Preoperatorios/métodos , Administración Oral , Catárticos/administración & dosificación , Análisis Costo-Beneficio , Electrólitos/administración & dosificación , Femenino , Procedimientos Quirúrgicos Ginecológicos , Humanos , Náusea/inducido químicamente , Cooperación del Paciente , Fosfatos/administración & dosificación , Polietilenglicoles/administración & dosificación , Vómitos/inducido químicamenteRESUMEN
Ovarian carcinoma is a malignancy with a poor prognosis especially in patients with advanced disease. The majority of patients with ovarian serous carcinoma are diagnosed in advanced stages. Palpable extraabdominal lymphadenopathy at the time of presentation is distinctly uncommon. This case report addresses a patient with serous ovarian carcinoma presenting as left supraclavicular lymphadenopathy (Virchow's node) and no other symptoms. Not only thyroid or thoracic malignancies but also ovarian malignancies like serous ovarian carcinoma could present with a supraclavicular lymph node without any other symptoms.
Asunto(s)
Adenocarcinoma Papilar/secundario , Cistadenocarcinoma Seroso/secundario , Ganglios Linfáticos/patología , Enfermedades Linfáticas/etiología , Neoplasias Ováricas/diagnóstico , Neoplasias Ováricas/patología , Adenocarcinoma Papilar/diagnóstico , Cistadenocarcinoma Seroso/complicaciones , Femenino , Humanos , Metástasis Linfática , Persona de Mediana EdadRESUMEN
OBJECTIVE: This study aimed to investigate and speculate on the dietary habits and certain environmental factors of the Southeast Anatolia region which are thought to be related with fetal anomaly development. MATERIALS AND METHODS: Patients admitted to Gaziantep University Faculty of Medicine Obstetrics and Gynecology Department with fetal anomalies between January 2003 and June 2007 were evaluated. Three hundred and fifteen patients with intrauterine fetal anomaly were detected. The number of total deliveries during this period were 7,554. Twenty-eight of the patients were above the age of 35. According to the history of patient, mean gravidity was 6.6 (1-13), consanguineous marriage rate was 25%, previous abnormal rate was 15%, and previous missed abortion was 35%. Eighty-eight percent of patients were of low sociocultural status. The frequency of daily dietary habits, especially tea consumption, red chili pepper consumption and eating barbecued meat were questioned with the anamnesis. RESULTS: Total fetal anomaly incidence was found to be 4.17%, neural tube defects 1.37%, renal anomalies 0.54%, non-immune fetal hydrops 0.46%, cystic hygroma 0.39%, central nervous system anomalies 0.36%, chromosomal anomalies 0.17%, gastrointestinal system anomalies 0.147%, sacrococcygeal teratoma 0.12%, cardiac anomalies 0.09%, and respiratory system anomalies 0.049%. Mean daily tea comsumption during pregnancy was 8 cups/day. Mean frequency of eating barbecued meat was 4 times/week. Mean chili pepper consumption was 10 g/day. CONCLUSION: In this study, four times higher overall fetal anomaly incidence appeared to be strongly correlated with Southeast Anatolia region's dietary habits. In the future monitoring women's dietary habits should have an important role in the prevention of fetal anomaly development.
Asunto(s)
Anomalías Congénitas/etiología , Conducta Alimentaria , Embarazo , Adolescente , Adulto , Estudios de Cohortes , Anomalías Congénitas/epidemiología , Femenino , Humanos , Incidencia , Persona de Mediana Edad , Efectos Tardíos de la Exposición Prenatal , Estudios Retrospectivos , Factores de Riesgo , Turquía/epidemiología , Adulto JovenRESUMEN
A total of 56 semen samples was collected from men in the ICSI program. The female partners of all men were under 35 years of age. Sperm chromatin integrity was evaluated by staining the spermatozoa with acridine orange. > 56% red fluorescence was taken as abnormal chromatin status. A significant negative association was found between the percentage of sperm with DNA fragmentation and fertilization rate. Increased red fluorescence indicated impaired fertilization outcome. Good quality embryo rates were significantly lower in abnormal AO stained group. Chromatin damage precedes the loss of fertilization potential and poor embryo quality.