RESUMEN

Disseminated cutaneous leishmaniasis (DCL) is an uncommon form of Leishmania braziliensis infection. It remains unknown why some people develop this clinical condition. We describe 14 DCL patients in Northeast Brazil during 2015-2018. These patients regularly drank large amounts of alcohol, possibly increasing their risk for DCL.

Asunto(s)

Alcoholismo , Leishmania braziliensis , Leishmaniasis Cutánea , Brasil/epidemiología , Etanol , Humanos , Leishmaniasis Cutánea/diagnóstico , Leishmaniasis Cutánea/epidemiología

RESUMEN

Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.

Asunto(s)

Complicaciones Infecciosas del Embarazo , Infección por el Virus Zika/congénito , Infección por el Virus Zika/diagnóstico , Virus Zika , Autopsia , Encéfalo/patología , Encéfalo/virología , Brasil , Femenino , Humanos , Recién Nacido , Microcefalia , Fenotipo , Embarazo , Virus Zika/clasificación , Virus Zika/genética , Infección por el Virus Zika/virología