RESUMEN

OBJECTIVE: The evaluation of the efficiency of corneal cross linking in the management of corneal ulcers. METHOD: A prospective study that included 10 patients, 10 eyes, with chronic corneal ulcer, bacterial and/ or fungal. The patients were divided into two groups. Group A included 5 patients with unperforated corneal ulcer and group B included 5 patients with perforated corneal ulcer. These patients were treated with general and local antibiotic and antifungal drugs, but the response was poor after two weeks. The crosslinking procedure was performed and the local treatment was continued for two weeks. An additional partial or total conjunctival coverage was done on group B. Patients were evaluated after 3 days, one week, two weeks, one month, 3 months, 6 months and one year after the procedure. Slit lamp and tomographic aspects of the cornea were assessed as well as the visual acuity. RESULTS: All ten patients experienced a decrease in pain from the first postoperative day. The ulcer healed by more than 50% in the first week in 3 patients from group A and closed completely after one month for 4 patients in group A, respectively 4 patients in group B. Hypopyon did not reappear after the crosslinking procedure in group A. However, it did persist in one patient from group B. Postoperative results were the same at 3, 6 and 12 months after the procedure. An opacification of the lens was observed in 3 patients after crosslinking. There were not any intra operative and postoperative complications. CONCLUSION: Corneal crosslinking is efficient in the management of patients with chronic corneal ulcer.

Asunto(s)

Antibacterianos/uso terapéutico , Antifúngicos/uso terapéutico , Queratitis/tratamiento farmacológico , Queratitis/microbiología , Adulto , Úlcera de la Córnea/tratamiento farmacológico , Úlcera de la Córnea/microbiología , Quimioterapia Combinada , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Fotoquimioterapia/métodos , Estudios Prospectivos , Lámpara de Hendidura , Resultado del Tratamiento , Agudeza Visual

RESUMEN

Objects: To investigate the variability of the corneal hysteresis in primary open angle glaucoma(POAG) patients. Material and Methods: Out of 123 eyes, 99 carried out the inclusion criteria and were investigated further using Goldman Aplanotonometer to measure intraocular pressure(IOP), Ocular Response Analyzer(ORA) in order to determine corneal hysteresis (CH) and corneal resistance factor(CRF), ultrasonic pachimetry (Ocuscan) to measure central corneal thickness(CCT) and Humphrey visual field to determine mean deviation(MD), pattern standard deviation(PSD) and visual field index(VFI). The patients were divided into two groups: one group of diagnosed POAG patients and one control group of healthy individuals. Statistical analysis was performed using descriptive analyses and linear regression. Results: A considerable statistic correlation was found between CH and VFI both in the group of primary open angle glaucoma patients(r=0.52, P<0.0001), and the control group (r=0.22, p<0.04). Conclusions: The study shows a positive correlation, statistically significant, between corneal hysteresis and visual field index both in glaucoma patients and control subjects proving that a lower CH associates with a lower VFI. Ocular response analyzer can be considered a useful instrument in evaluation of primary open angle glaucoma patients.