Asunto(s)
Historia de la Enfermería , Experimentación Humana , Medicina Tropical , Cuba , Historia del Siglo XIX , Humanos , Inmunización , Filatelia , Estados Unidos , Guerra , Fiebre AmarillaRESUMEN
Plasma FSH, LH, estradiol (E2) and progesterone (P4) profiles and patterns of follicular growth and regression by ultrasonography were determined after E2 treatment (1 microg/kg) in anestrous ewes. Fifteen ewes were treated with one (group I, n=7) or two (group II, n=4) i.m. injections of E2 with a 24h interval, or two oil injections with a 24h interval (group C, n=4). Blood samples for E2, P4, FSH and LH determinations were collected daily 4 days before the initiation of the treatment (day 0), when bleeding increased to every 2h starting 2h before treatment until 56h after the first injection and from then on every 6h until day 8, and twice per day till the end of the experiment (day 9). During the experimental period (days -4 to 9), transrectal ultrasonic examinations were carried out daily using a 7.5 MHz linear array probe. Number and size of follicles > or =3mm in diameter were recorded. No estrous was detected before, during or after treatment. LH and FSH surges were observed 10-18h after the first E2 injection. The second E2 injection stimulated another release of LH but no surges. E2 inhibited FSH levels before the surge and the second E2 injection induced a longer inhibition. No ovulation was detected by ultrasonography during the experimental period and P4 levels remained low (<0.7 nmol/l) before, during and after the treatment in all ewes. There was an effect of E2 treatment on the diameter of the largest follicle, a decrease could be observed 3 days after the first injection in both ewes of groups I and II. The E2-treated groups had a higher frequency of ewes showing wave emergence on day 3 (day 1.5+/-1,2.4+/-0.4 and 2.5+/-0.5 for control, groups I and II). LH and FSH surges were observed after E2 treatment, but were not able to provoke ovulation neither luteinization. In contrast, the treatment was associated with the regression of the largest follicle and with emergence of a new follicular wave on day 3.
Asunto(s)
Anestro , Estradiol/farmacología , Gonadotropinas/sangre , Folículo Ovárico/fisiología , Ovinos/fisiología , Animales , Estradiol/administración & dosificación , Estradiol/sangre , Femenino , Hormona Folículo Estimulante/sangre , Hormona Luteinizante/sangre , Folículo Ovárico/diagnóstico por imagen , Progesterona/sangre , UltrasonografíaRESUMEN
Las catecolaminas urinarias fueron determinadas en niños que presentaban deficit atencional con hiperactividad (DAH) de acuerdo al manual de diagnostico y estadistica. (DSM III-1983). No se encontraron diferencias significativas entre las tasas de excrecion de cada catecolamina en el grupo total de hiperactivos y el grupo control normal. Sin embargo, la excrecion de noradrenalina en los niños que presentaban DAH mas signos neurologicos sutiles DCM fue significativamente mas baja que la de los controles. Los resultados fueron interpretados como indicadores de una hipoactividad simpatica en los niños de una DCM (disfuncion cerebral minima)