RESUMEN
Gelatinous drop-like corneal dystrophy is a rare disorder with few cases described in the present literature. The following report will show how difficult it is to diagnose this disease in early stages. Modern image exams, such as optical coherence tomography helps to diagnose and can be crucial to establish the best treatment. We will present the histopathological changes and clinical features in this unusual dystrophy.
A distrofia corneana gelatinosa em gotas é uma desordem rara e pouco descrita em nossa literatura. O caso apresentado demonstra a dificuldade de realizar o diagnóstico nas fases mais iniciais da doença. O uso de modernos exames de imagem, como a tomografia de coerência óptica de segmento anterior, auxilia no diagnóstico e pode ser crucial para definir a melhor conduta terapêutica. Apresentaremos as alterações histopatológicas e as características clínicas desta incomum distrofia.
Asunto(s)
Preescolar , Femenino , Humanos , Amiloidosis Familiar/diagnóstico , Córnea/patología , Distrofias Hereditarias de la Córnea/diagnóstico , Amiloidosis Familiar/patología , Distrofias Hereditarias de la Córnea/patología , Tomografía de Coherencia ÓpticaRESUMEN
Gelatinous drop-like corneal dystrophy is a rare disorder with few cases described in the present literature. The following report will show how difficult it is to diagnose this disease in early stages. Modern image exams, such as optical coherence tomography helps to diagnose and can be crucial to establish the best treatment. We will present the histopathological changes and clinical features in this unusual dystrophy.
Asunto(s)
Amiloidosis Familiar/diagnóstico , Córnea/patología , Distrofias Hereditarias de la Córnea/diagnóstico , Amiloidosis Familiar/patología , Preescolar , Distrofias Hereditarias de la Córnea/patología , Femenino , Humanos , Tomografía de Coherencia ÓpticaRESUMEN
A retinosquise juvenil ligada ao cromossomo X é uma degeneração vítreorretiniana hereditária e recessiva. Sua manifestação ocular é a maculopatia cística bilateral e a delaminação das camadas de fibras nervosas da retina. Nenhuma intervenção terapêutica se mostrou eficiente para estabilizar a acuidade visual nestes pacientes. O artigo relata o caso clínico de um paciente portador de retinosquise juvenil ligada ao cromossomo X, que foi tratado com o uso tópico da dorzolamida, um colírio inibidor da anidrase carbônica.
X-linked juvenile retinoschisis is a hereditary and recessive vitreous-retinal disease. The main ophthamic manifestation is the bilateral macular cystic-like stellate maculopathy and splitting of the retina between the nerve fiber and ganglion cell layers. There were no treatments with efficacy in order to estabilize the visual acuity in the affected patients. This article presents a clinical case of a patient with a bilateral X- linked juvenil retinoschisis who was treated by the use of topical dorzolamide, a carbonic anhydrase inhibitor.
Asunto(s)
Humanos , Masculino , Adulto , Agudeza Visual/fisiología , Edema Macular/tratamiento farmacológico , Retinosquisis/tratamiento farmacológico , Sulfonamidas/uso terapéuticoRESUMEN
PURPOSE: To determine the applicability of the international revised diagnostic criteria for Vogt-Koyanagi-Harada disease. METHODS: Retrospective study. Medical charts of 140 patients with the diagnosis of Vogt-Koyanagi-Harada disease, from the Uveitis Sector of the Federal University of Sao Paulo (UNIFESP), were revised and classified following the revised diagnostic criteria. RESULTS: Of the 140 patients, 12.85% fulfilled the criteria for complete disease, 29.28% incomplete disease, 28.57% "probable" Vogt-Koyanagi-Harada disease and 28.27% were considered not Vogt-Koyanagi-Harada disease. CONCLUSION: The authors consider that the international revised diagnostic criteria have good applicability and are very useful to help in the diagnosis of Vogt-Koyanagi-Harada disease.
Asunto(s)
Técnicas de Diagnóstico Oftalmológico , Síndrome Uveomeningoencefálico/diagnóstico , Brasil , Humanos , Reproducibilidad de los Resultados , Estudios Retrospectivos , Sensibilidad y Especificidad , Síndrome Uveomeningoencefálico/clasificaciónRESUMEN
PURPOSE: To determine the applicability of the international revised diagnostic criteria for Vogt-Koyanagi-Harada disease. METHODS: Retrospective study. Medical charts of 140 patients with the diagnosis of Vogt-Koyanagi-Harada disease, from the Uveitis Sector of the Federal University of Sao Paulo (UNIFESP), were revised and classified following the revised diagnostic criteria. RESULTS: Of the 140 patients, 12.85 percent fulfilled the criteria for complete disease, 29.28 percent incomplete disease, 28.57 percent "probable" Vogt-Koyanagi-Harada disease and 28.27 percent were considered not Vogt-Koyanagi-Harada disease. CONCLUSION: The authors consider that the international revised diagnostic criteria have good applicability and are very useful to help in the diagnosis of Vogt-Koyanagi-Harada disease.
OBJETIVO: Determinar a aplicabilidade do "Internacional revised diagnostic criteria for Vogt-Koyanagi-Harada disease". MÉTODOS: Estudo retrospectivo. Prontuários de 140 pacientes com diagnóstico de "Vogt-Koyanagi-Harada disease", do setor de uveítes da Universidade Federal de São Paulo (UNIFESP), foram revisados e classificados segundo o "Internacional revised diagnostic criteria". RESULTADOS: Dos 140 pacientes, 12,85 por cento preencheram os critérios para doença completa, 29,28 por cento doença incompleta, 28,57 por cento "provável" doença de Vogt-Koyanagi-Harada e 28,27 por cento foram consideradas como não sendo doença de Vogt-Koyanagi-Harada. CONCLUSÃO: Os autores consideraram que o "International revised diagnostic criteria" tem boa aplicabilidade e é muito útil no diagnóstico da doença de Vogt-Koyanagi-Harada.
Asunto(s)
Humanos , Técnicas de Diagnóstico Oftalmológico , Síndrome Uveomeningoencefálico/diagnóstico , Brasil , Reproducibilidad de los Resultados , Estudios Retrospectivos , Sensibilidad y Especificidad , Síndrome Uveomeningoencefálico/clasificaciónRESUMEN
PURPOSES: To evaluate the importance of objective examinations in conjunction with ocular history and orbital and periorbital anatomy, to identify patients at risk of developing a post-blepharoplasty dry eye complication. METHODS: A prospective study was performed on 29 patients with dermatochalasis who were studied before and three months after blepharoplasty. Changes in ocular symptoms, physical examination and in objective tests, like Schirmer's test, tear film break-up time and rose Bengal coloration were evaluated. RESULTS: No statistically significant alteration in results of objective tests, except Schirmer II test, was found between the pre- and postoperative period. Regarding eyelid anatomy, alterations in palpebral fissure and excursion of the upper eyelid were observed that were statistically significant postoperatively. CONCLUSIONS: It is possible to state that the palpebral fissure alterations happen frequently in patients submitted to esthetic blepharoplasty. It was also possible to conclude, by this study, that the objective tests for dry eye evaluation, did not show significant alterations postoperatively, except for Schirmer II test.
Asunto(s)
Blefaroplastia/métodos , Cutis Laxo/complicaciones , Síndromes de Ojo Seco/etiología , Párpados/cirugía , Adulto , Anciano , Cutis Laxo/cirugía , Síndromes de Ojo Seco/diagnóstico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Valor Predictivo de las Pruebas , Cuidados Preoperatorios , Estudios Prospectivos , Factores de Riesgo , Rosa BengalaRESUMEN
PURPOSES: To evaluate the importance of objective examinations together with ocular history and orbital and periorbital anatomy, to identifying patients at risk of developing a post-blepharoplasty dry eye complication. METHODS: A prospective study was performed on 29 patients with dermatochalasis that were studied before and three months after blepharoplasty. Changes in ocular symptoms, physical examination and in objective tests, like Schirmer's test, tear film break-up time and rose bengal coloration were evaluated. RESULTS: No statistical significant alteration in results of objective tests, except Schirmer II test, between pre and postoperative period were found. In relation to eyelid anatomy, alterations in palpebral fissure and in excursion of the upper eyelid, that were statistically significant were found after surgery. CONCLUSIONS: It may be stated that palpebral fissure alterations occur frequently in patients submitted to esthetic blepharoplasty. It is also possible to conclude, that in this study, the objective tests for dry eye evaluation, did not demonstrate significant postoperative alterations, except for Schirmer II test.
Asunto(s)
Blefaroplastia/efectos adversos , Síndromes de Ojo Seco/etiología , Enfermedades de los Párpados/cirugía , Adulto , Anciano , Síndromes de Ojo Seco/diagnóstico , Femenino , Colorantes Fluorescentes , Humanos , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Cuidados Preoperatorios , Estudios Prospectivos , Rosa Bengala , Factores SexualesRESUMEN
OBJETIVOS: Avaliar a importância dos exames objetivos, da história ocular, além da anatomia orbitária e periorbitária, na identificação dos pacientes com risco de desenvolver olho seco no pós-operatório da blefaroplastia. MÉTODOS: Realizado estudo prospectivo em 29 pacientes com dermatocálaze, que foram avaliados antes e três meses após a blefaroplastia. Mudanças nos sintomas oculares, no exame físico e nos testes objetivos (teste de Schirmer, tempo de quebra do filme lacrimal e coloração com rosa bengala), foram avaliadas. RESULTADOS: Não foram encontradas alterações estatisticamente significativas nos resultados dos testes objetivos, à exceção do teste de Schirmer II, entre o pré e o pós-operatório. Em relação às modificações na anatomia palpebral, foram observadas alterações na fenda palpebral e na excursão do músculo levantador da pálpebra superior, que foram estatisticamente significativas no pós-operatório. CONCLUSÕES: Podemos afirmar que as modificações da fenda palpebral acontecem com elevada freqüência nos pacientes submetidos à blefaroplastia estética. Pode-se concluir ainda que, no presente estudo, os exames objetivos para a avaliação do olho seco não demonstraram alterações significativas no pós-operatório, à exceção do teste de Schirmer II.