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Introduction: There are several risk factors associated with developing mental disorders among people over 60 years of age. Mental health encompasses multiple domains or capacities, which can comprise the psychological wellbeing of older people. Therefore, resilient coping, self-compassion, self-esteem, hopelessness, quality of life, and depression are considered the characteristics and adaptive mechanisms that bring together the main risk and protective factors for imbalance in mental wellbeing. Objective: This study aimed to establish the demographic, social, and family factors, as well as the clinical characteristics and lifestyle habits that influence the mental health of the elderly people in the city of Medellín, in the year 2021, to build a mental health index. Methodology: This study adopts a quantitative approach, employs retrospective temporality, and utilizes secondary sources. A cross-sectional survey was carried out with the SABAM Project (health and mental wellbeing of older adults from five cities in Colombia in 2021 by its Spanish acronym) database (secondary source), which is part of the research group "Public Health Observatory" of CES University (Medellín, Colombia). The database comprised 500 records of people aged over 60 years from the city of Medellín in 2021. While constructing the index, a principal component analysis was used, along with the Varimax method for factor analysis rotation. Results: The median age of the general population was 67 years (IQR 63-72); for men, the median age was 66 years (IQR 63-71) and for women, the median age was 67 years (IQR 63-72). An association was found between low socioeconomic levels, alcohol consumption, and the level of higher education (university-postgraduate) with low levels of the Mental Health Index in people over 60 years of age in Medellín during the year 2021. Conclusion: A quantitative model was developed to predict either a positive or negative prognosis in the mental wellbeing of the population over 60 years of age in the city of Medellín. The model was also used for the development of a sociodemographic profile highlighting the impact on mental health among people over 60 years of age with limited economic resources.

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Introducción: Anualmente se pierden 1,35 millones de vidas por causa de siniestros viales; su ocurrencia se ha relacionado, además de factores comportamentales, con desigualdades sociales. Objetivo: Analizar las desigualdades sociales urbano-rurales en la mortalidad por siniestros viales en Colombia para el periodo 1998-2019. Materiales y métodos: Estudio ecológico a partir del análisis de las tasas de mortalidad ajustadas de los grupos poblacionales urbanos y rurales estratificados por sexo. Se hicieron análisis con regresión de Joinpoint y se calcularon medidas de desigualdad simple absoluta y relativa. Resultados: Se registraron 139 323 muertes por siniestros viales, en Colombia la tasa de mortalidad por esta causa se ha venido reduciendo. En contraste con las áreas rurales, en las áreas urbanas esta reducción es más significativa. Existen desigualdades en la mortalidad entre las áreas urbanas y rurales que han venido estrechándose. No obstante, en el caso de hombres y mujeres ha venido incrementándose. Discusión: La reducción de la tasa de mortalidad por siniestros viales sugiere que las intervenciones en seguridad vial han sido efectivas. La mayor mortalidad en hombres puede explicarse a partir de factores comportamentales. Las desigualdades urbano-rurales pueden estar relacionadas con las dinámicas de desarrollo. Conclusiones: Se registra una reducción en la tasa de mortalidad por siniestros viales, la cual es más significativa en áreas urbanas. Existen desigualdades urbano-rurales en la mortalidad por esta causa. Las políticas de seguridad vial deben partir de un enfoque integrador vinculado con otras agendas políticas.

Introduction: Annually, 1,35 million lives are lost due to road accidents; their occurrence has been related, in addition to behavioral factors, to social inequalities. Objective: To analyze urban-rural social inequalities in mortality from traffic accidents in Colombia from 1998-2019. Methods and materials: Ecological study based on the analysis of standardized mortality rates adjusted for age and sex of urban and rural population groups stratified by sex. Joinpoint regression analyses were performed, and absolute and relative simple inequality measures were calculated. Results: There were 139.323 deaths from road accidents; in Colombia mortality rates from this cause has been decreasing. In urban areas, the reduction is more significant than in rural areas. Disparities in mortality between urban and rural areas have been narrowing, however, in the case of men and women, they have been increasing. Discussion: Reducing the mortality rate from road accidents suggests that road safety interventions have been effective. Behavioral factors can explain the higher mortality in men. Urban-rural inequalities can be related to development dynamics. Conclusions: There is a significant reduction in the mortality rate due to road accidents in urban areas. There are urban-rural inequalities in mortality from this cause. Road safety policies must be based on an integrative approach linked to other political agendas.

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OBJECTIVE: To synthesize the social inequalities related to mortality from traffic accidents reported in scientific publications. METHOD: A scoping review following the PRISMA-ScR guide was carried out. Using the MesH vocabulary, we systematically searched for articles in English, Portuguese and Spanish published in the EBSCO, Scielo, Scopus, Ovid, and PubMed databases. RESULTS: We identified 47,790 records in the initial search, of which 35 articles met the selection criteria. Nine out ten publications are in high-income countries; there is a greater interest in analyzing mortality in occupants and drivers of vehicles and motorcyclists. Half of the publications use race-ethnicity and geolocation as socioeconomic position variables. The articles included in this review indicate that groups of people with low socioeconomic positions have higher mortality due to traffic accidents. CONCLUSIONS: The highest mortality from traffic accidents occurs in people with low socioeconomic positions which suggests the development of road safety actions from a comprehensive, integrative perspective and linked to other political agendas to reduce their incidence by 2030. Although road traffic fatalities are higher in low and middle-income countries, few publications are available in these countries. It is necessary to strengthen the research capacities in these countries.

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Objetivo: Construir un índice que determine la vulnerabilidad sexual de las mujeres trans. Material y Método: Estudio mixto realizado entre los años 2020 y 2021 que en su primera fase utilizó el análisis de contenido para textos que describían los conceptos básicos de vulnerabilidad, vulnerabilidad social y riesgo, apoyado con los relatos obtenidos en grupos focales y entrevistas a 14 mujeres transgénero para generar el constructo teórico de vulnerabilidad sexual de las mujeres transgénero. Para la segunda parte, a partir de la información recolectada de 417 mujeres transgénero de las ciudades de Bogotá y Cali que habían participado del estudio "Vulnerabilidad y Prevalencia de VIH en Mujeres Transgénero en tres ciudades de Colombia: Bogotá, Medellín y Santiago de Cali-2019", se seleccionaron las variables que serían parte de un análisis factorial exploratorio para construir la versión preliminar del índice. Resultados: Se construyó el índice de riesgo de vulnerabilidad sexual de las mujeres transgénero compuesto por 3 factores: apoyo social, prácticas sexuales y cuidado de la salud. El índice consta de 10 preguntas que se evalúan como 0 o 1, donde los puntajes más altos evidencian un mayor riesgo de vulnerabilidad sexual. Conclusiones: La vulnerabilidad sexual es un fenómeno construido por factores propios de la experiencia trans e influenciado por las características del contexto donde la persona habita; el índice construido cuenta con buena consistencia interna (alfa ordinal 0,90). Asimismo, se encontró concordancia entre el modelo teórico de la fase cualitativa y los resultados del análisis factorial exploratorio.

Objective: To construct an index to determine the sexual vulnerability of trans women. Materials and Methods: Mixed study conducted between 2020 and 2021, which in its first phase used content analysis for texts describing the basic concepts of vulnerability, social vulnerability and risk. This was supported by accounts from focus groups and interviews with 14 transgender women to generate the theoretical construct of sexual vulnerability of transgender women. For the second phase, from the information provided by 417 transgender women from the cities of Bogotá and Cali, who participated in the study "Vulnerability and HIV Prevalence in Transgender Women in three cities of Colombia: Bogota, Medellin and Santiago de Cali - 2019", variables were selected to be part of an exploratory factor analysis to construct the preliminary version of the index. Results: The sexual vulnerability risk index of transgender women was based on 3 factors: social support, sexual practices, and health care. The index consisted of 10 questions scored as 0 or 1, with higher scores indicating a higher risk of sexual vulnerability. Conclusions: Sexual vulnerability is a phenomenon based on factors which are specific to the trans experience and it is influenced by the characteristics of the context in which the person lives. The constructed index has good internal consistency (ordinal alpha 0.90) and shows concordance between the theoretical model of the qualitative phase and the results of the exploratory factor analysis.

Objetivo: Construir um índice para determinar a vulnerabilidade sexual de mulheres transgênero. Material e Método: Estudo misto realizado entre 2020 e 2021 que, em sua primeira fase, utilizou a análise de conteúdo para textos que descrevem os conceitos básicos de vulnerabilidade, vulnerabilidade social e risco; apoiado por relatos obtidos em grupos focais e entrevistas com 14 mulheres transgênero para gerar o construto teórico de vulnerabilidade sexual de mulheres transgênero. Para a segunda fase, a partir das informações fornecidas por 417 mulheres transgênero das cidades de Bogotá e Cali que participaram do estudo "Vulnerabilidade e Prevalência de HIV em Mulheres Transgênero em três cidades da Colômbia: Bogotá, Medellín e Santiago de Cali-2019", foram selecionadas variáveis que fizeram parte de uma análise fatorial exploratória para construir a versão preliminar do índice. Resultados: O índice de risco de vulnerabilidade sexual de mulheres transgênero foi construído com base em três fatores: apoio social, práticas sexuais e assistência à saúde. Consiste em 10 perguntas que são avaliadas como 0 ou 1, em que as pontuações mais altas evidenciam um risco maior de vulnerabilidade sexual. Conclusões: A vulnerabilidade sexual é um fenômeno baseado em fatores que são específicos da experiência trans e é influenciado pelas características do contexto em que a pessoa vive. Além disso, o índice construído tem boa consistência interna (alfa ordinal 0,90) e mostra concordância entre o modelo teórico da fase qualitativa e os resultados da análise fatorial exploratória.

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Introduction: Although studies about informal work have been carried out, there is still little evidence that explains, from the workers' perspective, what pressures they receive and generate due to the use of public space, and how these pressures affect their health. Objectives: To explore, from the point of view of a group of informal workers from the downtown Medellin, the environmental and social pressures that they receive and generate from the use of the territory, as well as the effects that these pressures may have on their life and health conditions. Methods: Ethnographic tools were used for field work and grounded theory for data analysis. Twelve informal street vendors workers were selected through theoretical sampling, with whom in-depth interviews and focus groups were conducted, after obtaining consent from the verbal and written process. Interviews and focus groups were transcribed verbatim, with the help of janitors and informants. The results were discussed and validated with the workers, and the information was triangulated with the researchers. Open and axial coding was used for data analysis. Results: The environmental and social pressures that these workers receive and generate in the streets and sidewalks of the city led them to experience critical situations in their working conditions, partly derived from the conflict that occurs over the use of the territory with the different actors in the downtown area, a situation that directly affects workers' physical and mental conditions, their life, and their work. Conclusions: The conflicts generated by the use of the territory as a workplace imply that workers have hostile relationships in their daily lives. However, these conflicts could be resolved with actions of the State and the participation of workers.

Introduction: Aunque se han realizado estudios acerca del trabajo informal, aun es escasa la evidencia que explique, desde la mirada de los trabajadores, qué presiones reciben y generan por el uso del espacio público y cómo estas presiones les afectan su salud. Objetivos: Explorar, desde la mirada de un grupo de trabajadores informales del centro de Medellin, las presiones ambientales y sociales que reciben y generan por el uso del territorio, así como los efectos que pueden tener estas presiones en sus condiciones de vida y salud. Métodos: Se utilizaron herramientas etnográficas para el trabajo de campo y de teoria fundamentada para el análisis de datos. Se tomaron mediante muestro teórico a 12 trabajadores informales "venteros", con quienes se realizaron entrevistas en profundidad y grupos focales, previa toma de consentimiento de proceso verbal y escrito. Se transcribieron las entrevistas y grupos focales de manera textual, se contó con porteros e informantes clave. Los resultados fueron discutidos y validados con los trabajadores, y se trianguló la información con los investigadores. Se utilizó codificación abierta y axial para el análisis de datos. Resultados: Las presiones ambientales y sociales que reciben y generan estos trabajadores en las calles y aceras de la ciudad los llevan a vivenciar situaciones críticas en sus condiciones laborales, derivadas, en parte, del conflicto que se da por el uso del territorio con los diferentes actores del centro de la ciudad, situación que afecta directamente las condiciones de salud física y mental de los trabajadores, su vida y su labor. Conclusiones: Los conflictos que se generan por el uso del territorio como lugar de trabajo implican que los trabajadores tengan relaciones hostiles en su cotidianidad. Sin embargo, estos conflictos podrían revertirse con acciones del Estado y la participación de los trabajadores.

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Este artículo pretende explorar el concepto de antifragilidad en el adulto mayor, dado el cambio demográfico en el mundo, con evidencia del aumento de personas mayores, que exige a los profesionales vinculados a su atención implementar modelos de intervención acordes con sus necesidades, relacionadas con su capacidad funcional y promoción de una cultura de antifragilidad. La construcción teórica de lo que significa ser adulto mayor antifrágil, en una sociedad que asimila el envejecimiento con fragilidad, enfermedad y discapacidad, es una oportunidad para presentar una mirada positiva de la salud en la vejez, a partir de las adaptaciones al estrés en diferentes dimensiones que influencian la vida de este grupo poblacional, en el que el capital físico, psicológico y social se integran e influencian, en un proceso que se relaciona con la antifragilidad y el envejecer como un continuo de la vida, con ganancias y pérdidas; el estudio de esta relación permitirá contar con políticas inclusivas adecuadas en cada etapa de la vida.

This article intends to explore the concept of anti-fragility in the elderly, given the demographic change in the world, with evidence of the increase in the number of elderly people, which requires professionals linked to their care, to implement intervention models in accordance with their needs, related to their functional capacity and promotion of a culture of antifragility. The theoretical construction of what it means to be an anti-fragile older adult, in a society that assimilates aging with frailty, illness and disability, is an opportunity to present a positive view of health in old age, based on the adaptations to stress in different dimensions that influence the life of this population group, in which physical, psychological and social capital are integrated and influenced, in a process that is related to anti-fragility and aging as a continuum of life, with gains and losses; the study of this relationship will make it possible to have appropriate inclusive policies at each stage of life.

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RESUMEN Objetivo: Determinar las condiciones laborales y extralaborales relacionadas con los síntomas depresivos de trabajadoras informales del centro de Medellín en 2015-2019. Métodos: Estudio transversal con intención analítica y fuentes primarias de información. Toma de datos con encuesta asistida en una de sus sedes gremiales en 2016, después de prueba piloto y estandarización de encuestadores. Se tomó por censo a 291 trabajadoras y se exploraron sus características laborales y extralaborales. Resultados: Las mujeres tenían una media de edad de 45 arios, escolaridad < 5 años, viviendas en estrato bajo y medio e ingresos inferiores al salario mínimo de 2016. Alrededor del 60,0% tenía inseguridad alimentaria moderada-grave, sin subsidio del Estado; eran fundamentalmente cabezas de familia, con 2 o menos personas a su cargo, y responsables de sus labores en el hogar. Laboraban al menos 8h al día 6 o 7 días a la semana, con padres o parientes venteros, y al menos 20 años en su labor. Alrededor del 60,0% tenía pareja, el 21,6% con disfuncionalidad familiar, y el 15,4% sufría síntomas depresivos moderados-graves (MG). Se asociaron y aportaron a la explicación de síntomas depresivos MG, vivir en cuarto o inquilinato, en estrato socioeconómico bajo y tener disfuncionalidad familiar MG. Conclusiones: Las condiciones extralaborales que se asocian y explican los síntomas depresivos MG de las trabajadoras pueden modificarse con acciones que impacten en los determinantes sociales de la salud.

ABSTRACT Objective: To determine the working and non-working conditions related to depressive symptoms in informal workers in the centre of Medellín in 2015-2019. Methods: Cross-sectional study with analytical intention and primary sources of information. Data collection with assisted survey in one of its union headquarters in 2016, after a pilot test and standardisation of pollsters. A total of 291 women workers were taken as a census, and their working and non-working conditions were explored. Results: The women had an average age of 45 years, <5 years of schooling, low and middle-income housing, and income below the 2016 minimum wage. About 60% suffered moderate-severe food insecurity, and received no state benefits. They were mainly the head of the family, with 1 or 2 dependents, and were responsible for the work at home. They worked at least 8 hours a day, 6 or 7 days a week, with parents or relatives selling in the street, and at least 20 years in their work. About 60% had a partner, 21.6% with family dysfunction, and 15.4% moderate-severe depressive symptoms. Living in one room or a slum, with a low socioeconomic status and moderate-severe family dysfunction were associated with, and contributed to the explanation of, moderate-severe depressive symptoms. Conclusions: The non-working conditions that are associated with and explain the moderate-severe depressive symptoms of female workers can be modified with actions that impact on the social determinants of health.

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Resumen Los esfuerzos de la Organización Mundial de la Salud por trascender los modelos biomédicos y comportamentales para la explicación de la salud han resaltado el bienestar como elemento clave en esta tarea. La inclusión del concepto de bienestar en las definiciones de salud mental ha provocado, en muchas ocasiones, la utilización de ambos conceptos como sinónimos, sin embargo, difícilmente el bienestar por sí solo puede dar cuenta de la salud mental de una persona. Este artículo de reflexión tiene como objetivo presentar el concepto de capacidad desde el campo del desarrollo humano, como respuesta a las limitaciones que presentan los modelos de bienestar, y los aportes que tendría su utilización en la construcción de una definición de salud mental a partir del enfoque socioeconómico y en la consolidación de una estrategia de promoción de la salud mental.

Abstract The efforts of the World Health Organization to transcend biomedical and behavioral explanations of health have highlighted well-being as a key element in this task. The inclusion of well-being concept in mental health definitions has caused, on many occasions, the use of both concepts as synonyms, however, well-being cannot hardly define by its own a person's mental health. This article aims to introduce the concept of capacity from the field of human development as a response to the limitations presented by well-being models and the contributions that their implementation would have in the construction of a definition for mental health from the socioeconomic approach and consolidate a strategy to promote mental health.

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OBJECTIVE: This study aimed to explore the housing and residential environment conditions associated with functional autonomy in older persons. METHODS: A quantitative cross-sectional study was conducted, including 175 individuals over the age of 60. Participants were non-institutionalized urban residents of Medellín, Colombia, selected by random two-stage sampling (neighborhoods and blocks). Analysis was done according to functional autonomy of action (dependent variable); and demographic conditions, housing, and the physical and social environment suggested by the World Health Organization (WHO) in the strategy of age-friendly cities (independent variables). Univariate, bivariate, and multivariate analyses were performed with these variables, where the odds ratio (OR), association hypothesis test, and confidence intervals were estimated, using logistic regression models. RESULTS: 89.7% of older persons had moderate physical performance. The performance of intergenerational activities (OR = 5.28) and community actions (OR = 11.28) were part of social environments. The adaptations in public transport (OR = 90.33), sanitary services (OR = 4.1), and lighting in parks (OR = 19.9) of the physical environment were the associations found with functional autonomy. CONCLUSIONS: Exploring how the physical and social environments surrounding housing are associated with the functional performance of older persons can generate useful information to support public health and city infrastructure strategies that improve their physical performance and maintain autonomy.

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Resumen El objetivo de este estudio fue analizar mediante el modelo Rasch las evidencias de validez de la medida de funcionalidad familiar obtenida a partir del APGAR-familiar en adultos mayores de Colombia. Se encuestaron 1.514 participantes residentes en Medellín, Barranquilla y Pasto. Se realizaron análisis Rasch de ajuste de categorías de respuesta, ajuste de los ítems y de las personas, funcionamiento diferencial de los ítems, dimensionalidad e independencia local de los ítems y confiabilidad. Los principales resultados indicaron que el formato de respuesta se ajusta a los requerimientos de optimización de función de Linacre, todos los ítems muestran medias cuadráticas Infit y Outfit en el rango esperado, la escala es unidimensional y la confiabilidad de Wright se estimó en 0,962. Se concluye que, en adultos mayores colombianos, el APGAR-familiar proporciona una medida de funcionalidad familiar unidimensional, a nivel de intervalo, confiable e insesgada por edad y sexo, que permite clasificar cinco niveles de funcionalidad familiar con fines de tamizaje.

Abstract The objective of this study was to analyze, using the Rasch model, the evidence of validity of the measure of family functionality obtained from the APGAR-family assessment in older adults in Colombia. A total of 1,514 participants residing in Medellín, Barranquilla and Pasto were surveyed. Rasch analysis of adjustment of response categories, adjustment of items and people, differential functioning of the items, dimensionality and local independence of the items and reliability were carried out. The main results indicated that the response format conforms to the Linacre function optimization requirements. All the items show Infit and Outfit means square in the expected range. The scale is one-dimensional and Wright's reliability was estimated at 0.962. It is concluded that the APGAR-family assessment in Colombian older adults provides a one-dimensional measure of family functionality at the interval level, reliable and unbiased by age and gender, which allows classifying five levels of family functionality for screening purposes.

Resumo O objetivo deste estudo foi analisar através do modelo Rasch as evidencias de validez da medida de funcionalidade familiar obtida a partir do APGAR-familiar em adultos maiores da Colômbia. Entrevistaram-se 1.514 participantes residentes em Medellín, Barranquilla e Pasto. Fizeram-se análises Rasch de ajuste de categorias de resposta, ajuste dos itens e das pessoas, funcionamento diferencial dos itens, dimensionalidade e independência local dos itens e confiabilidade. Os principais resultados indicaram que o formato de resposta se ajusta aos requerimentos de optimização de função de Linacre, todos os itens amostram medias quadráticas Infit e Outfit no rango esperado, a escada é unidimensional e a confiabilidade de Wright se estimou em 0,962. Conclui que, em adultos maiores colombianos, o APGAR-familiar proporciona uma medida de funcionalidade familiar unidimensional, a nível de intervalo, confiável e imparcial por idade e sexo, que permite classificar cinco níveis de funcionalidade familiar com fins de triagem.

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Aedes aegypti is the main vector of the dengue virus in Colombia. Some factors have been associated with its presence; however, in the local context, it has not been sufficiently evaluated. The present study seeks to identify the socioeconomic, environmental, and behavioral factors associated with the presence and abundance of A. aegypti in urban dwellings in the municipality of Castilla la Nueva. A cross-sectional cohort study was conducted in houses in the urban area of the municipality of Castilla la Nueva, where 307 houses were sampled by systematic random sampling during May 2018. A multifactorial survey was used to measure the socioeconomic, environmental, and behavioral factors as explanatory variables. The infestation and relative abundance were established by the presence of larval stages and ovitraps. The associated factors for the presence and abundance of A. aegypti were identified using negative binomial and logistic regression models. A positive housing infestation of 33.2% was identified by direct inspection and 78.5% with ovitraps. The main factors positively associated with the presence and abundance of A. aegypti were one-story homes (PR = 2.26; 95% CI: 1.31-3.87), the storage of water for domestic use (PR = 1.91; 95% CI: 1.18-3.09), and local conditions such as disorganized backyard (PR = 79.95; 95% CI: 10.96-583.24) and the proportion of shade greater than 50% of the backyard (PR = 62.32; 95% CI: 6.47-600.32). And, it is negatively associated with residential gas service (PR = 0.3; 95% CI: 0.16-0.58) and self-administered internal fumigation (PR = 0.37; 95% CI: 0.2-0.69). The presence and abundance of A. aegypti were explained by interrelated socioeconomic, environmental, and behavioral factors where local conditions and habits such as the organization of the patio, knowledge about vector biology, and cleaning containers are identified as main topics for future prevention strategies for the transmission of dengue in the local and national context.

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BACKGROUND: To date, there is no specific antiviral therapy for severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) that causes Coronavirus disease 2019 (Covid-19). Since there is no specific therapy against SARS-CoV2, current efforts aim to prevent contagion through public health measures and develop a protective vaccine. While waiting for the latter, it is necessary to evaluate the drugs that at least, in initial studies, suggested some degree of utility in the management of Covid-19 or its complications. The main objective of the study was to describe the clinical manifestations and outcomes of patients with severe Covid-19 Pneumonia treated with corticosteroids and colchicine. MATERIALS AND METHODS: A cross sectional study of 301 adult patients with Covid-19 Pneumonia confirmed by Real-Time Polymerase Chain Reaction for SARS-CoV2 (RT-PCR SARS-CoV2), Berlin protocol, who required hospitalization in three hospitals in Antioquia, Colombia. Patients were treated according to the institutional protocol (from March 20, 2020 to June 30, 2020) with corticosteroid if the patient required supplemental oxygen. From July 1, 2020, the management protocol changed with the addition of colchicine to all patients admitted to the institutions. The treatment was supervised and monitored by the same specialist in Infectology of the institutions. We describe the clinical manifestations and outcomes of the patients who received these treatments. The information of the patients was analyzed according to the outcome of interest (alive/dead) with univariate, bivariate, and multivariate measures to adjust the variables that presented statistical association. RESULTS: All patients had pneumonia documented by chest computed tomography with ground glass images and presented an alveolar pressure/inspired oxygen fraction (PaFi) less than 300. Three hundred one patients were included, 240 (79.7%) received corticosteroids, within these 145 (48.2%) received colchicine also, and the remaining 61 (20.3%) patients did not receive corticosterioids or colchicine. Mortality in the group that received colchicine was lower compared to the group that did not receive it (9.6 vs 14.6%, p-value = 0.179). CONCLUSIONS: Treatment with corticosteroids and colchicine for managing patients with severe Covid-19 Pneumonia was associated with low mortality at the hospital level. Randomized, placebo-controlled studies are required to evaluate the effect of corticosteroids and colchicine on complications or death from Covid-19.

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INTRODUCTION: Occupational diseases are those that may have a causal relationship with occupational activity or environment. However, this definition does not specify how this disease would be identified and acknowledged for workers with subsistence jobs. OBJECTIVES: To determine sociodemographic, labor and environmental conditions that collaborate to explain the presence of eye and skin irritation among informal vendors in downtown Medellin. METHODS: Descriptive cross-sectional study with analytical intention, primary sources of information, and administration of assisted survey including self-reported eye and skin irritation in 686 workers. RESULTS: Predominantly male population with mean age of 50 (±11.8) years. A total of 23.5 % of workers had worked as vendors for their entire life; 37.5% had worked as vendors for 11 to 20 years as vendors; and 81.5%worked for more than 8 hours a day. According to 69.8% of the sample, poor air quality affected their work, and 80.0% believed that pollution was generated by vehicle fleet. The polluted areas generated unpleasant odors (50.2%) and air pollution (89.4%). The prevalence of eye and skin irritation was 65.4%. Not having working license and having fair, poor, or very poor job tenure significantly reduced the prevalence of eye and skin irritation. Conversely, exposure to polluted water, working in the professional for more than 30 years, male sex, and age older than 60 years were associated with increased prevalence of irritation. CONCLUSIONS: Eye and skin irritation was mainly explained by non-modifiable sociodemographic and labor conditions and by consumption of polluted water; however, implementing public health actions could reduce workers' socio-environmental and labor vulnerability.

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BACKGROUND: There is no effective therapy for the severe acute respiratory syndrome by coronavirus 2 (SARS-CoV2) responsible for the Coronavirus disease 2019 (Covid-19). To date, dexamethasone has shown a decrease in mortality in patients who require oxygen, especially those with invasive mechanical ventilation. However, it is unknown if another corticosteroid can be used, the optimal dose and its duration, to achieve a better clinical outcome. The objective of the study was to compare the differences in clinical outcome and laboratory results in hospitalized patients with severe SARS-CoV2 Pneumonia treated with dexamethasone at 6 mg doses versus patients treated with high-dose methylprednisolone. MATERIALS AND METHODS: Ambispective cohort study with survival analysis of 216 patients diagnosed with severe Covid-19 pneumonia confirmed by polymerase chain reaction for SARS-CoV2 by Berlin protocol, who were hospitalized in a high-complexity clinic in Medellín, Colombia. The patients should also have supplementary oxygen and radiological confirmation of Pneumonia by chest tomography. Sample size was not calculated since the total population that met the inclusion criteria was evaluated. 111 patients were treated with the institutional protocol with intravenous dexamethasone 6 mg QD for seven to 10 days if they required oxygen. Since September 15, 2020, the hospitalization protocol of the clinic was modified by the Infectious Diseases and Pulmonology service, recommending a high dose of methylprednisolone of 250 to 500 mg every day for three days with a subsequent change to oral prednisone 50 mg every day for 14 days. The protocol was not applied in the intensive care unit, where dexamethasone continued to be administered. The clinical outcome and differences in laboratory results of the patients who received dexamethasone vs. the prospective cohort that received methylprednisolone from September 15 to October 31, 2020, were evaluated. Follow-up was carried out by outpatient consultation one month after discharge or by telephone, inquiring about readmission or living-dead status. RESULTS: 216 patients had Covid-19 pneumonia documented by ground-glass imaging and alveolar pressure / inspired oxygen fraction (PaFi) less than 300. 111 patients received dexamethasone (DXM) and 105 received methylprednisolone (MTP). Patients in the DXM group evolved to severe ARDS in a higher proportion (26.1% vs 17.1% than the MTP group). Upon completion 4 days of treatment with parenteral corticosteroid, laboratory markers of severity decreased significantly in the group that received MTP, CRP 2.85 (2.3-3.8) vs 7.2 (5.4-9.8), (p-value < 0.0001), D-dimer 691 (612-847) vs 1083 (740-1565) (p-value = 0.04) and DHL 273 (244-289) vs 355 (270.6-422) (p-value = 0.01). After starting the corticosteroid, transfer to the intensive care unit (4.8% vs. 14.4%) and mortality (9,5% vs. 17.1%) was lower in the group that received MTP. Recovery time was shorter in patients treated with MTP, three days (3-4) vs. DXM 6 days (5-8) (p-value < 0.0001). At 30-day follow-up, 88 (92.6%) were alive in MTP vs 58 (63.1%) of those who received dexamethasone. CONCLUSIONS: In this study, the treatment of severe Covid-19 Pneumonia with high-dose methylprednisolone for three days followed by oral prednisone for 14 days, compared with 6 mg dexamethasone for 7 to 10 days, statistically significantly decreased the recovery time, the need for transfer to intensive care and the severity markers C-reactive protein (CRP), D-dimer and LDH. Randomized controlled studies with methylprednisolone are required to corroborate its effect, and studies in a population hospitalized in intensive care wards.

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Resumen La calidad de vida está compuesta por elementos subjetivos y objetivos que varían entre la población, para su adecuada medición se han generado diversos instrumentos con el propósito de obtener una adecuada medición. Objetivo: identificar las dimensiones de calidad de vida que se han evaluado en personas trans. Métodos: revisión sistemática de la literatura científica aplicando un protocolo de investigación con términos de búsqueda "quality of life" y "transgender"; realizada por cuatro investigadores para verificar la información encontrada. Resultados: inicialmente se identificaron 565 artículos, después de un proceso de revisión se eligieron 34 publicados entre los años 2006 y 2018. Se encontraron 13 herramientas para medir la calidad de vida en población trans. Las más utilizadas fueron las genéricas (38,2%), las de calidad de vida relacionada con la salud (35,3%) y las relacionadas con la voz (20,6%), las dimensiones más evaluadas fueron la física, la psicológica y la social. Conclusión: la calidad de vida en esta población debe medirse de manera más ajustada teniendo en cuenta las realidades de dicho grupo humano. Se identificó un bajo número de instrumentos de calidad de vida diseñados específicamente para las personas trans.

Abstract The quality of life is composed of subjective and objective elements that vary among the population. Various instruments have been generated for its adequate measurement with the purpose of obtaining an adequate measurement. Objective: To identify the dimensions of quality of life that have been evaluated in transgender people. Methods: Systematic review of the scientific literature carried out by three researchers applying a research protocol with the search terms "quality of life" and "transgender" to verify the information found. Results: A total of 565 articles were identified initially after a review process, from which 34, published between 2006 and 2018, were chosen. Thirteen tools were found to measure the quality of life in the transgender population. The most used were generic (38.2%), healthrelated quality of life (35.3%) and those related with the voice (20.6%). The dimensions most evaluated were physical, psychological and social. Conclusion: The quality of life in this population should be measured more closely, taking into account the realities of that human group. A low number of quality of life instruments designed specifically for transgender people were identified.

Resumo A qualidade de vida é composta por elementos subjetivos e objetivos que variam na população para sua adequada medição. Tem sido gerados diversos instrumentos com o propósito de obter uma adequada medição. Objetivo: identificar as dimensões de qualidade de vida que têm sido avaliadas em pessoas trans. Métodos: revisão sistemática da literatura científica aplicando um protocolo de pesquisa com termos de busca "quality of life" e "transgender"; realizada por quatro pesquisadores para verificar a informação encontrada. Resultados: inicialmente foram identificadas 565 artigos, depois de um processo de revisão foram escolhidas 34 publicações entre os anos 2006 e 2018. Encontraram-se 13 ferramentas para medir a qualidade de vida na população trans. As mais utilizadas foram as genéricas (38,2%), as de qualidade de vida relacionada com a saúde (35,3%) e as relacionadas com a voz (20,6%), as dimensões mais avaliadas foram a física, a psicológica e a social. Conclusão: a qualidade de vida nesta população deve medir-se de maneira mais ajustada levando em conta as realidades desse grupo humano. Identificou-se um baixo número de instrumentos de qualidade de vida desenhados especificamente para as pessoas trans.

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Low birth weight (LBW) is a global problem that annually affects nearly 20 million children, 96% of these in developing countries. According to the WHO, the poorest and the ethnic minorities are the groups most affected by this indicator. A cross-sectional study of the database of all newborns officially registered in Colombia in 2008-2014 was done. While dichotomizing the mestizo population and ethnic minorities (Afro-descendants, indigenous, ROM), normal and low birth weight was used as the dependent variable and ethnicity as the explanatory variable. Other variables of the parents and the newborns were used as covariates. To assess associations, bivariate and multivariate logistic regression analyses were performed. The incidence of LBW among newborns registered in Colombia fluctuated at around 9%. Among the ethnic minorities, the probability of LBW, adjusted for other variables, was significantly higher (OR 1.07, 95% CI 1.05-1.08) than among mestizos. A significantly higher risk of LBW to newborns in the ethnic minorities' group, and those with unfavorable socioeconomic conditions, was found.

RESUMEN: El bajo peso al nacer (BPN) es un problema global que afecta anualmente a casi 20 millones de niños, el 96% de estos en países en desarrollo. Según la OMS, las más pobres y las minorías étnicas son los grupos más afectados por este indicador. Se realizó un estudio transversal de la base de datos de todos los recién nacidos registrados oficialmente en Colombia en 2008-2014. La población fue dicotomizaba en mestiza y minorías étnicas (afrodescendientes, indígenas, ROM). Se utilizó Bajo Peso al Nacer (BPN) como variable dependiente y el origen étnico como variable explicativa. Otras variables de los padres y los recién nacidos se utilizaron como covariables. Para evaluar las asociaciones, se realizaron análisis de regresión logística bivariada y multivariada. La incidencia de BPN entre los recién nacidos registrados en Colombia fluctuó alrededor del 9%. Entre las minorías étnicas, la probabilidad de LBW, ajustada por otras variables, fue significativamente mayor (OR = 1.07, 95% _CI: 1.05-1.08) que entre los mestizos. Se encontró un riesgo significativamente más alto de BPN para los recién nacidos en el grupo de minorías étnicas y aquellos con condiciones socioeconómicas desfavorables.

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Resumen Algunas personas en procesos de reintegración mayores (PPRM) que participaron en la guerra presentan alteraciones mentales explicadas por el largo tiempo desescola rizados y las situaciones vividas, que le disminuyen la posibilidad de acceso al campo laboral y a la sociedad, el funcionamiento cognitivo alterado fue más prevalente en personas sin educación formal, sin pareja o vivir en familias no funcionales. Entre los factores demográficos de las PPRM que aumentan la probabilidad de tener un sínto ma depresivo fue pertenecer al sexo masculino, tener más de 65 años, no contar con apoyo de una pareja y disminuye esta probabilidad si se cuenta con algún grado de escolaridad. De los factores familiares y sociales que se analizaron, solo se encontró que vivir con una familia no funcional aumenta el riesgo de sufrir síntomas depre sivos. Por lo que se requiere acompañamiento para la aceptación de su proceso de envejecimiento, el aprovechamiento de experiencias y el ejercicio de la ciudadanía.

Abstract Some Senior Citizens in Reintegration Processes (PPRM), who participated in war have mental disturbances explained by the long de-schooling and living situations, which decrease the possibility of accessing the workforce and society. Altered cognitive func tioning was more prevalent in people without formal education, without a partner, or living in non-functional families. Among the PPRM demographic factors of PPRM, which increase the likelihood of having a depressive symptom was belonging to the male sex, being over 65 years old, not having support from a partner. This likelihood decreases if there is any degree of schooling. Among the family and social factors discussed, only living with a non-functional family was found to increase the risk of depressive symptoms. Thus, accompaniment is required for the acceptance of their aging process, the use of experiences, and the exercise of citizenship.

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INTRODUCTION: Suicidal ideation refers to thoughts that range from a vague idea of committing suicide to a specific suicide plan. OBJECTIVE: To explore factors such as demographic, social, family, abuse, risk of depression, habits and health conditions, which influence suicidal ideation in the elderly people in the cities of Medellín, Barranquilla, and Pasto (Colombia), with the intention to identify those associated factors that can be used in public health programs focused on this population. METHODS: Cross-sectional analytical study was conducted using a secondary source, demographic, social, clinical variables, social support, discrimination, abuse, happiness, depression, functional capacity, and as a dependent variable were asked the question: "Have you ever thought about committing suicide?" A descriptive, bivariate and multivariate analysis was performed. RESULTS: The median age was ≤ 69 [interquartile range, 11] years, and 58.2% were women. The prevalence of suicidal ideation was 6.4%, and of these, 28.7% had made plans to end their lives, and 66.7% had tried at least once. A statistical association was found with informal employment, cigarette consumption, alcohol and psychoactive substances, risk of depression, having a disability, dissatisfaction with their quality of life, with their health, with their economic situation, as well as feeling unhappy, bad treatment and bad relationships among family members, poor social support, sexual and economic abuse, and finally, discrimination. CONCLUSIONS: Suicidal ideation in older adults in three cities of Colombia is explained by the sexual and economic abuse that this population is suffering, as well as bad personal relationships between the members of the family of the older adult. The risk of depression increases the probability of having thoughts against one's life.

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RESUMEN Introducción: La ideación suicida se refiere a pensamientos que abarcan desde una vaga idea de suicidarse a un plan específico de suicidio. Objetivo: Explorar factores demográficos, sociales y familiares, maltrato, riesgo de depresión y hábitos y condiciones de salud que influyen en la ideación suicida del adulto mayor en las ciudades de Medellín, Barranquilla y Pasto, para identificar aquellos en los que se puede intervenir con programas de salud pública enfocados en esta población. Métodos: Estudio analítico transversal con fuente secundaria; se consideraron variables demográficas, sociales y clínicas, apoyo social, discriminación, maltrato, felicidad, depresión y capacidad funcional, y como variable dependiente, la pregunta: «¿ha pensado en atentar contra su vida?¼. Se realizaron análisis descriptivo, bivariable y multivariable. Resultados: La mediana de edad fue ≤ 69 (intervalo intercuartílico, 11) años; el 58,2% eran mujeres; la prevalencia de ideación suicida fue del 6,4%; el 28,7% de estos había hecho planes para terminar con su vida y el 66,7% lo había intentado al menos una vez. Se encontró asociación estadística con el empleo informal, el consumo de cigarrillos, alcohol y sustancias psicoactivas, el riesgo de depresión, tener discapacidad, la insatisfacción con la calidad de vida, la salud y la situación económica, sentirse infeliz, los maltratos y las malas relaciones entre los miembros de la familia, el escaso apoyo social, el maltrato sexual y económico y, por último, la discriminación. Conclusiones: La ideación suicida de los adultos mayores en 3 ciudades de Colombia se explica por el maltrato sexual y económico que sufre esta población; asimismo las malas relaciones personales entre los miembros de la familia del adulto mayor y el riesgo de depresión aumentan la probabilidad de que se presenten pensamientos contra la propia vida.

ABSTRACT Introduction: Suicidal ideation refers to thoughts that range from a vague idea of committing suicide to a specific suicide plan. Objective: To explore factors such as demographic, social, family, abuse, risk of depression, habits and health conditions, which influence suicidal ideation in the elderly people in the cities of Medellín, Barranquilla, and Pasto (Colombia), with the intention to identify those associated factors that can be used in public health programs focused on this population. Methods: Cross-sectional analytical study was conducted using a secondary source, demographic, social, clinical variables, social support, discrimination, abuse, happiness, depression, functional capacity, and as a dependent variable were asked the question: "Have you ever thought about committing suicide?" A descriptive, bivariate and multivariate analysis was performed. Results: The median age was ≤ 69 [interquartile range, 11] years, and 58.2% were women. The prevalence of suicidal ideation was 6.4%, and of these, 28.7% had made plans to end their lives, and 66.7% had tried at least once. A statistical association was found with informal employment, cigarette consumption, alcohol and psychoactive substances, risk of depression, having a disability, dissatisfaction with their quality of life, with their health, with their economic situation, as well as feeling unhappy, bad treatment and bad relationships among family members, poor social support, sexual and economic abuse, and finally, discrimination. Conclusions: Suicidal ideation in older adults in three cities of Colombia is explained by the sexual and economic abuse that this population is suffering, as well as bad personal relationships between the members of the family of the older adult. The risk of depression increases the probability of having thoughts against one's life.

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Resumen Los malos tratos hacia las personas mayores están influenciados por patrones culturales, el contexto histórico, el entorno sociocultural y los juicios de valor que la sociedad construye en torno a la vejez. El maltrato a esta población no ha tenido la misma resonancia en la sociedad que el ejercido a niños y mujeres; sin embargo, en los últimos años ha comenzado a ser visible como un problema de interés público. La presente revisión tiene como objetivo presentar los principales conceptos y características del maltrato al adulto mayor y describir la magnitud de este fenómeno social en el mundo y en Colombia desde 1975 hasta 2018.

Abstract Abuse towards older people is influenced by cultural patterns, the historical context, the socio-cultural environment and the value judgments that society builds around old age. The mistreatment of this population has not had the same resonance in society as the abuse of children and women; however, in recent years it has started to be seen as a problem of public interest. This review aims to present the main concepts and characteristics of elder abuse and describe the magnitude of this social phenomenon worldwide and in Colombia from 1975 until 2018.

Resumo Os maus-tratos aos idosos estão influenciados por padrões culturais, o contexto histórico, o ambiente sociocultural e os juízos de valor que a sociedade constrói ao redor da velhice. Os maus-tratos dirigidos a esta população não têm tido a mesma repercussão na sociedade que o exercido às crianças e mulheres; porém, nos últimos anos se tornou mais visível como um problema de interesse público. A presente revisão tem como objetivo apresentar os principais conceitos e características dos maus-tratos ao idoso e descrever a extensão desse fenômeno social na Colômbia e no mundo desde 1975 até 2018.