RESUMEN
This study aims at investigating the effect of an experimental period of intake of whole grain foods rich in lignans as part of an habitual diet on the plasma and urinary excretion of enterolignans, the biomarkers of lipid metabolism and the immunological and antioxidant status in a group of postmenopausal women with moderate serum cholesterol. A randomized double-blind crossover study was completed on 13 subjects in 12-weeks after protocol approval of an ethical committee. The subjects consumed whole grain foods high in lignans (30 g/d of breakfast cereals or biscuits, etc., 80 g/d of whole grain pasta) or refined grain foods for 4 weeks, separated by a 2-weeks wash-out period. A modest hypocholesterolemic effect (p < 0.05) of the whole grain diet was observed and the intake of whole grain products rich in lignans was also associated with an increase in urinary enterodiol excretion (p < 0.05).
Asunto(s)
Colesterol/sangre , Grano Comestible/química , Lignanos/administración & dosificación , Posmenopausia , Presión Sanguínea , Índice de Masa Corporal , Peso Corporal , Estudios Cruzados , Dieta , Método Doble Ciego , Femenino , Glutatión Peroxidasa/sangre , Humanos , Interleucina-1beta/sangre , Interleucina-6/sangre , Italia , Lignanos/orina , Persona de Mediana Edad , Proyectos Piloto , Superóxido Dismutasa/sangre , Factor de Necrosis Tumoral alfa/sangreRESUMEN
Excess dietary sodium chloride (salt) intake is etiologically related to hypertension and cardiovascular disease (CVD). Moderate reduction of salt intake reduces blood pressure (BP) and is expected to contribute to reduce the risk of CVD. Previous community-based trials to reduce BP by means of salt reduction were very successful. The initial positive results of national strategies of dietary salt intake reduction in several European countries, driven by the initiative of the World Health Organisation (WHO) and non-governmental organisations such as the World Action of Salt and Health (WASH), have paved the way for action in other European Union (EU) member states. In Italy, several initiatives aiming at reduction of salt intake at the population level have been recently undertaken. These initiatives include i) the evaluation of current dietary habits promoted by the Working Group for Dietary Salt Reduction in Italy (GIRCSI); ii) the chemical analysis of the bread salt content, a major source of sodium intake in Italy, and the agreement between the bakers' associations and the Ministry of Health for a gradual reduction of the bread salt content; iii) the implementation of educational campaigns to increase population awareness, iv) the involvement of the food catering system. In the immediate future, food reformulation must be extended to other food categories in collaboration with industry, foods' salt targets ought to be defined, the food labelling system must be improved and population salt awareness must be further increased through educational campaigns. The GIRCSI Working Group is committed to pursue these objectives.
Asunto(s)
Enfermedades Cardiovasculares/prevención & control , Dieta Hiposódica , Hipertensión/terapia , Programas Nacionales de Salud , Cloruro de Sodio Dietético/administración & dosificación , Pan/análisis , Enfermedades Cardiovasculares/etiología , Medicina Basada en la Evidencia , Conducta Alimentaria , Industria de Alimentos/legislación & jurisprudencia , Educación en Salud , Política de Salud , Humanos , Hipertensión/etiología , Italia , Programas Nacionales de Salud/legislación & jurisprudencia , Política Nutricional , Desarrollo de ProgramaRESUMEN
A study was undertaken to investigate the effect of technological processing in pasta-making on the content of arsenic, cadmium, lead and nickel. Milling of durum wheat as well as further processing were carried out in a pilot plant. Commercial pasta samples purchased from the local market were also included for comparison. Furthermore, the effect of cooking was investigated to gain information on the actual content of the selected elements in the final ready-to-eat product. Analyte concentrations in whole grain, semolina, pasta and cooked pasta were determined by inductively coupled plasma-mass spectrometry. Milling reduced the element content in the order nickel > arsenic > cadmium > lead. In the experimental conditions of this study, slight contamination by atmospheric lead in milling/pasta-making and release of nickel during pasta-making were observed. These issues have evidently been effectively dealt with in industrial processing given that remarkably lower levels of lead and nickel were found in commercial pastas compared with the experimental samples. On the whole, commercial pasta samples showed low average levels of all the elements included in this study. Cooking caused a significant decrease of the element content in all pasta samples, with average losses of 50-60% on a dry weight basis.
Asunto(s)
Contaminación de Alimentos/análisis , Manipulación de Alimentos , Metales/análisis , Triticum , Arsénico/análisis , Cadmio/análisis , Humanos , Plomo/análisis , Níquel/análisisRESUMEN
Sample contamination as a consequence of abrasion of grinding tools during the homogenization of food materials to be analysed for trace elements was addressed. The possible release of 15 trace elements (Al, As, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Se, Sn, V, Zn) from six different grinding and milling devices, operating either continuously or discontinuously, was evaluated. All the devices were commercially available and were representative of models usually employed in food and agricultural laboratories. Wheat grains belonging to one soft and one durum cultivar were used as test material. The determination of the analyte concentrations in subsamples submitted to the different preparation treatments was performed by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS). Accordingly, a suitable digestion method was developed and the ArC+ interference affecting Cr determination was evaluated and corrected. Statistical differences with respect to the control were detected for 10 elements (Al, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb) and in most cases contamination of the samples was traced back to the composition of the grinding equipment. None of the investigated devices was contamination-free with respect to all of the quantified elements. Abrasion of the grinding tools was higher with durum wheat than with soft wheat as a consequence of their different hardiness.
Asunto(s)
Contaminación de Alimentos , Manejo de Especímenes/métodos , Oligoelementos/análisis , Triticum/química , Análisis de Varianza , Manipulación de Alimentos/métodos , Humanos , Espectrometría de Masas , Control de CalidadRESUMEN
A survey was carried out with the aim to assess the levels of some toxic (cadmium, lead) and essential (copper, zinc) trace metals in wheat grown in Italy. A total of 178 samples of soft wheat grain and 239 samples of durum wheat grain from all the Italian wheat-growing regions were pooled into 35 and 38 representative samples respectively. After dry ashing, cadmium and lead were determined by graphite furnace atomic absorption spectrometry (GFAAS), whereas copper and zinc were determined by flame atomic absorption spectrometry (FAAS). In soft wheat the mean and median contents of all samples were (on a dry weight basis) 40 and 33 micrograms kg-1 for cadmium, 16 and 14 micrograms kg-1 for lead, 3.4 and 3.2 mg kg-1 for copper, 33 and 32 mg kg-1 for zinc. Similar levels were found in durum wheat. In this latter case the mean and median were 42 and 39 micrograms kg-1 for cadmium, 15 and 14 micrograms kg-1 for lead, 3.5 and 3.2 mg kg-1 for copper, 34 and 34 mg kg-1 for zinc. Significant differences were detected for some metals in relation to geographical provenance and variety. The average intake of the four selected elements from wheat-based products was estimated for the Italian population.