RESUMEN

We identified 10 individuals who had undiagnosed human immunodeficiency virus type 1 (HIV-1) infection at the time of smallpox vaccination. Mean CD4 cell count was 483 cells/mm3 (range, 286-751 cells/mm3), and mean log10 plasma HIV-1 RNA load was 4.13 copies/cm3 (range, 2.54-5.16 copies/cm3). All vaccinees (3 primary and 7 repeat) had a normal, robust reaction without complications. Smallpox vaccine was well-tolerated in this small series of HIV-1-infected military personnel.

Asunto(s)

Recuento de Linfocito CD4 , Infecciones por VIH/inmunología , VIH-1/fisiología , Personal Militar , ARN Viral/sangre , Vacuna contra Viruela/administración & dosificación , Adulto , Infecciones por VIH/terapia , VIH-1/efectos de los fármacos , VIH-1/genética , Humanos , Masculino , Persona de Mediana Edad , ARN Viral/efectos de los fármacos , Vacuna contra Viruela/efectos adversos , Vacuna contra Viruela/inmunología , Estados Unidos , Vacunación