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1.
Phys Rev Lett ; 133(4): 040801, 2024 Jul 26.
Artículo en Inglés | MEDLINE | ID: mdl-39121399

RESUMEN

We compare critical quantum sensing to passive quantum strategies to perform frequency estimation, in the case of single-mode quadratic Hamiltonians. We show that, while in the unitary case both strategies achieve precision scaling quadratic with the number of photons, in the presence of dissipation this is true only for critical strategies. We also establish that working at the exceptional point or beyond threshold provides suboptimal performance. This critical enhancement is due to the emergence of a transient regime in the open critical dynamics, and is invariant to temperature changes. When considering both time and system size as resources, for both strategies the precision scales linearly with the product of the total time and the number of photons, in accordance with fundamental bounds. However, we show that critical protocols outperform optimal passive strategies if preparation and measurement times are not negligible. Our results are applicable to a broad variety of critical sensors whose phenomenology can be reduced to that of a single-mode quadratic Hamiltonian, including systems described by finite-component and fully connected models.

2.
Sci Rep ; 8(1): 6416, 2018 Apr 23.
Artículo en Inglés | MEDLINE | ID: mdl-29686396

RESUMEN

Two-mode squeezing is a fascinating example of quantum entanglement manifested in cross-correlations of non-commuting observables between two subsystems. At the same time, these subsystems themselves may contain no quantum signatures in their self-correlations. These properties make two-mode squeezed (TMS) states an ideal resource for applications in quantum communication. Here, we generate propagating microwave TMS states by a beam splitter distributing single mode squeezing emitted from distinct Josephson parametric amplifiers along two output paths. We experimentally study the fundamental dephasing process of quantum cross-correlations in continuous-variable propagating TMS microwave states and accurately describe it with a theory model. In this way, we gain the insight into finite-time entanglement limits and predict high fidelities for benchmark quantum communication protocols such as remote state preparation and quantum teleportation.

3.
Sci Rep ; 7(1): 9333, 2017 08 24.
Artículo en Inglés | MEDLINE | ID: mdl-28839171

RESUMEN

In quantum illumination entangled light is employed to enhance the detection accuracy of an object when compared with the best classical protocol. On the other hand, cloaking is a stealth technology based on covering a target with a material deflecting the light around the object to avoid its detection. Here, we propose a quantum illumination protocol especially adapted to quantum microwave technology. This protocol seizes the phase-shift induced by some cloaking techniques, such as scattering reduction, allowing for a 3 dB improvement in the detection of a cloaked target. The method can also be employed for the detection of a phase-shift in bright environments in different frequency regimes. Finally, we study the minimal efficiency required by the photocounter for which the quantum illumination protocol still shows a gain with respect to the classical protocol.

4.
Phys Rev Lett ; 118(7): 070803, 2017 Feb 17.
Artículo en Inglés | MEDLINE | ID: mdl-28256851

RESUMEN

Quantum illumination consists in shining quantum light on a target region immersed in a bright thermal bath with the aim of detecting the presence of a possible low-reflective object. If the signal is entangled with the receiver, then a suitable choice of the measurement offers a gain with respect to the optimal classical protocol employing coherent states. Here, we tackle this detection problem by using quantum estimation techniques to measure the reflectivity parameter of the object, showing an enhancement in the signal-to-noise ratio up to 3 dB with respect to the classical case when implementing only local measurements. Our approach employs the quantum Fisher information to provide an upper bound for the error probability, supplies the concrete estimator saturating the bound, and extends the quantum illumination protocol to non-Gaussian states. As an example, we show how Schrödinger's cat states may be used for quantum illumination.

5.
Sci Rep ; 6: 30188, 2016 07 26.
Artículo en Inglés | MEDLINE | ID: mdl-27457273

RESUMEN

We propose an entanglement classification for symmetric quantum states based on their diagonal matrix-product-state (MPS) representation. The proposed classification, which preserves the stochastic local operation assisted with classical communication (SLOCC) criterion, relates entanglement families to the interaction length of Hamiltonians. In this manner, we establish a connection between entanglement classification and condensed matter models from a quantum information perspective. Moreover, we introduce a scalable nesting property for the proposed entanglement classification, in which the families for N parties carry over to the N + 1 case. Finally, using techniques from algebraic geometry, we prove that the minimal nontrivial interaction length n for any symmetric state is bounded by .

6.
Phys Rev Lett ; 117(2): 020502, 2016 Jul 08.
Artículo en Inglés | MEDLINE | ID: mdl-27447495

RESUMEN

Displacement of propagating quantum states of light is a fundamental operation for quantum communication. It enables fundamental studies on macroscopic quantum coherence and plays an important role in quantum teleportation protocols with continuous variables. In our experiments, we have successfully implemented this operation for propagating squeezed microwave states. We demonstrate that, even for strong displacement amplitudes, there is no degradation of the squeezing level in the reconstructed quantum states. Furthermore, we confirm that path entanglement generated by using displaced squeezed states remains constant over a wide range of the displacement power.

7.
Phys Rev Lett ; 116(7): 070503, 2016 Feb 19.
Artículo en Inglés | MEDLINE | ID: mdl-26943521

RESUMEN

Measuring entanglement is a demanding task that usually requires full tomography of a quantum system, involving a number of observables that grows exponentially with the number of parties. Recently, it was suggested that adding a single ancillary qubit would allow for the efficient measurement of concurrence, and indeed any entanglement monotone associated with antilinear operations. Here, we report on the experimental implementation of such a device-an embedding quantum simulator-in photonics, encoding the entangling dynamics of a bipartite system into a tripartite one. We show that bipartite concurrence can be efficiently extracted from the measurement of merely two observables, instead of 15, without full tomographic information.

8.
J Synchrotron Radiat ; 23(1): 59-66, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26698046

RESUMEN

Adjustable mirrors equipped with piezo actuators are commonly used at synchrotron and free-electron laser (FEL) beamlines, in order to optimize their focusing properties and sometimes to shape the intensity distribution of the focal spot with the desired profile. Unlike them, X-ray mirrors for astronomy are much thinner in order to enable nesting and reduce the areal mass, and the application of piezo actuators acting normally to the surface appears much more difficult. There remains the possibility to correct the deformations using thin patches that exert a tangential strain on the rear side of the mirror: some research groups are already at work on this approach. The technique reported here relies on actively integrating thin glass foils with commercial piezoceramic patches, fed by voltages driven by the feedback provided by X-rays, while the tension signals are carried by electrodes on the back of the mirror, obtained by photolithography. Finally, the shape detection and the consequent voltage signal to be provided to the piezoelectric array will be determined by X-ray illumination in an intra-focal setup at the XACT facility. In this work, the manufacturing steps for obtaining a first active mirror prototype are described.

9.
Sci Rep ; 5: 9981, 2015 May 29.
Artículo en Inglés | MEDLINE | ID: mdl-26024437

RESUMEN

We present a quantum algorithm to simulate general finite dimensional Lindblad master equations without the requirement of engineering the system-environment interactions. The proposed method is able to simulate both Markovian and non-Markovian quantum dynamics. It consists in the quantum computation of the dissipative corrections to the unitary evolution of the system of interest, via the reconstruction of the response functions associated with the Lindblad operators. Our approach is equally applicable to dynamics generated by effectively non-Hermitian Hamiltonians. We confirm the quality of our method providing specific error bounds that quantify its accuracy.

10.
J Eur Acad Dermatol Venereol ; 29(4): 656-62, 2015 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-25418531

RESUMEN

BACKGROUND: Psoriasis has been linked to an increased risk of metabolic syndrome (MetS). Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of MetS, is now the commonest liver disease worldwide and can evolve into cirrhosis in a subgroup of patients. Psoriasis has been reported to be associated to NAFLD. AIM: The aim of this study was to evaluate the strength of the association between psoriasis and NAFLD. METHODS: A systematic review of the literature was conducted in six databases (Medline, CINAHL, Scopus, LILACS, Cochrane Library and EMBASE). Data from studies assessing frequency of NAFLD in psoriatic and non-psoriatic patients were extracted and meta-analysed using the Mantel-Haenszel method. Subgroups analysis of patients with psoriatic arthritis and moderate to severe psoriasis was also performed. RESULTS: Seven case-control studies were included, all of them of low or moderate quality. Psoriatic patients exhibited an increased risk of NAFLD compared to non-psoriatic controls (six studies; n = 267,761 patients; odds ratio (OR): 2.15, 95% CI: 1.57-2.94). The association remained significant (OR: 2.07, 95% CI: 1.62-2.64) when only high/moderate quality studies were analysed (three studies; n = 3345 patients). The risk of NAFLD was significantly greater in patients with psoriatic arthritis (three studies; n = 505 patients; OR: 2.25, 95% IC: 1.37-3.71) and in patients with moderate to severe psoriasis compared to those with mild psoriasis (two studies; 51,930 patients, OR: 2.07, 95% CI: 1.59-2.71). LIMITATIONS: Data quality and heterogeneity may restrict the interpretation of the pooled risk estimates. CONCLUSION: Case-control studies support an association between psoriasis and NAFLD. Screening of NAFLD in this group of patients may be warranted.


Asunto(s)
Enfermedad del Hígado Graso no Alcohólico/epidemiología , Psoriasis/epidemiología , Artritis Psoriásica/epidemiología , Humanos , Factores de Riesgo , Índice de Severidad de la Enfermedad
11.
Phys Rev Lett ; 113(2): 020505, 2014 Jul 11.
Artículo en Inglés | MEDLINE | ID: mdl-25062155

RESUMEN

We propose a method for computing n-time correlation functions of arbitrary spinorial, fermionic, and bosonic operators, consisting of an efficient quantum algorithm that encodes these correlations in an initially added ancillary qubit for probe and control tasks. For spinorial and fermionic systems, the reconstruction of arbitrary n-time correlation functions requires the measurement of two ancilla observables, while for bosonic variables time derivatives of the same observables are needed. Finally, we provide examples applicable to different quantum platforms in the frame of the linear response theory.

12.
São Paulo; IDPC / USP; 2014. 65 p. il..
en Portugués | DANTEPAZZANESE, SESSP-IDPCPROD, Sec. Est. Saúde SP, SESSP-TESESESSP, Sec. Est. Saúde SP, SESSP-IDPCACERVO | ID: dan-4138
13.
Phys Rev Lett ; 111(24): 240502, 2013 Dec 13.
Artículo en Inglés | MEDLINE | ID: mdl-24483635

RESUMEN

We introduce the concept of embedding quantum simulators, a paradigm allowing the efficient quantum computation of a class of bipartite and multipartite entanglement monotones. It consists in the suitable encoding of a simulated quantum dynamics in the enlarged Hilbert space of an embedding quantum simulator. In this manner, entanglement monotones are conveniently mapped onto physical observables, overcoming the necessity of full tomography and reducing drastically the experimental requirements. Furthermore, this method is directly applicable to pure states and, assisted by classical algorithms, to the mixed-state case. Finally, we expect that the proposed embedding framework paves the way for a general theory of enhanced one-to-one quantum simulators.

14.
Phys Rev Lett ; 109(25): 250502, 2012 Dec 21.
Artículo en Inglés | MEDLINE | ID: mdl-23368439

RESUMEN

Path entanglement constitutes an essential resource in quantum information and communication protocols. Here, we demonstrate frequency-degenerate entanglement between continuous-variable quantum microwaves propagating along two spatially separated paths. We combine a squeezed and a vacuum state using a microwave beam splitter. Via correlation measurements, we detect and quantify the path entanglement contained in the beam splitter output state. Our experiments open the avenue to quantum teleportation, quantum communication, or quantum radar with continuous variables at microwave frequencies.

16.
Clin Exp Obstet Gynecol ; 22(2): 143-4, 1995.
Artículo en Inglés | MEDLINE | ID: mdl-7781181

RESUMEN

The social impact of menopause is stressed by the actual life expectancy of women. One of the most important post-menopausal alterations--"osteoporosis"--is considered. Particular attention is focussed on therapeutical aspects.


Asunto(s)
Calcitonina/uso terapéutico , Terapia de Reemplazo de Estrógeno , Estrógenos/uso terapéutico , Osteoporosis Posmenopáusica/prevención & control , Posmenopausia , Progestinas/uso terapéutico , Femenino , Humanos , Persona de Mediana Edad , Osteoporosis Posmenopáusica/terapia
17.
Clin Ther ; 10(5): 536-42, 1988.
Artículo en Inglés | MEDLINE | ID: mdl-2908803

RESUMEN

In a multicenter, double-blind trial, 63 elderly patients who had experienced a generalized anxiety disorder for at least one month were randomly assigned to receive 15 mg of ketazolam (n = 31) or placebo (n = 32) daily for 15 days. At the end of this period, if their total scores on the Hamilton Anxiety Rating Scale had decreased by at least 25%, treatment was continued unchanged for a further 15 days. Patients who did not respond to treatment were given an additional 15 mg of ketazolam daily. During the initial 15 days, 83% of the ketazolam-treated patients and 43% of the placebo patients responded to treatment (P < 0.01). During the second 15-day period, the anxiety scores of the ketazolam-treated patients continued to decline significantly, whereas the placebo patients showed no improvement. According to the investigators' assessments of severity of anxiety and patients' ratings of treatment effectiveness, ketazolam was significantly superior to placebo.


Asunto(s)
Ansiolíticos/uso terapéutico , Ansiedad/tratamiento farmacológico , Benzodiazepinas , Benzodiazepinonas/uso terapéutico , Anciano , Anciano de 80 o más Años , Ansiolíticos/efectos adversos , Benzodiazepinonas/efectos adversos , Relación Dosis-Respuesta a Droga , Método Doble Ciego , Esquema de Medicación , Femenino , Humanos , Masculino , Escalas de Valoración Psiquiátrica
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