RESUMEN
This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body adiposity through electrical bioimpedance considering body fat percentage (BFP), CAM through heart rate variability (considering RMSSD, SDNN, PNN50, LF (m2), HF (m2), SD1 indexes and SD1/SD2 ratio) and PA through a questionnaire in 64 participants (58.0 ± 9.6 years), recruited through the local association of support for breast cancer and by direct indications from city mastologists. After insertion of PA into the multivariate statistical model, significant attenuation was observed in the relationship between body adiposity and CAM for the indices: SDNN (ß = -0.94; 95 percent CI: -1.93; 0.04; p = .060) and SD1/SD2 (ß = -0.01;95 percent CI = -0.02; 0.001; p = .065). In conclusion, it was observed that PA was able to mitigate the relationships between BFP and CAM (considering SDNN index and SD1/SD2 ratio) in breast cancer survivors.
Asunto(s)
Neoplasias de la Mama , Supervivientes de Cáncer , Sindactilia , Humanos , Femenino , Adiposidad , Estudios Longitudinales , Obesidad , Ejercicio Físico/fisiología , Frecuencia Cardíaca/fisiologíaRESUMEN
PURPOSE: This study aimed to analyze the longitudinal influence of sitting time (ST) on cardiac autonomic modulation (CAM) and resting heart rate (RHR) in a 12-month cohort of 67 breast cancer survivors. METHODS: CAM was assessed by heart rate variability with heart monitor which also assessed RHR, and ST was self-reported. The relationship between the variables was analyzed by the Pearson correlation and its magnitude by linear regression. RESULTS: At baseline, no associations were found between ST and CAM or RHR. In the delta analyses, a decrease in RMSSD, SD1, and HF(ms2) was associated with sitting time. At 12-month follow-up, there was an increase in the ST and a decrease in RHR. ST was negatively related with CAM (RMSSD, PNN50, and SD1), but no association was observed between ST and RHR. CONCLUSION: The increase in ST was associated with worsening of CAM after 12-month follow-up. Promoting reduction in ST will be an important strategy against cardiovascular impairment in breast cancer survivors.
Asunto(s)
Neoplasias de la Mama , Supervivientes de Cáncer , Sistema Nervioso Autónomo , Neoplasias de la Mama/terapia , Estudios de Cohortes , Femenino , Frecuencia Cardíaca , Humanos , Conducta SedentariaRESUMEN
OBJECTIVES: Treatments for breast cancer (BC) can lead to physical and mental impairments which may affect quality of life (QoL). Physical activity (PA) is highly recommended for this population due to its protective effect against BC relapse and its ability to reduce the health impact of treatment. However, it is not clear whether the different domains of PA are associated with better QoL of BC survivors. The current study aimed to verify the relationship between different PA domains with QoL of BC survivors. METHODS: The sample consisted of 128 women BC survivors, with a mean age of 58.2â±â9.7âyears. QoL was assessed using the Short-Form Health Survey questionnaire (SF-36) and PA was verified through the Baecke questionnaire, in domains of occupation, sports practice, and leisure time/commuting. The relationship between QoL and different PA domains was verified by linear regression, adjusted by age, marital status, and socioeconomic condition. RESULTS: Occupational PA was negatively related to physical limitations [ß= -15.36 (-29.04 to -1.68] and body pain [ß=-6.61 (-14.53 to 1.31) marginal association]. Sports practice was positively related to functional capacity [ß= 4.24 (0.60 to 7.88)]. Leisure time/commuting PA was positively related to functional capacity [ßâ=â7.17 (3.09 to 11.26)], vitality [ßâ=â4.30 (0.39 to 8.22)], social aspects [ß= 5.47 (0.80 to 10.15)], and mental health [ßâ=â4.08 (0.40 to 7.75)]. CONCLUSIONS: Sports practice and leisure time/commuting PA were positively related to QoL in BC survivors, while occupational PA was negatively related to QoL, independently of age, marital status, and socioeconomic condition.