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3.
Minerva Anestesiol ; 58(4 Suppl 1): 117-9, 1992 Apr.
Artículo en Italiano | MEDLINE | ID: mdl-1620429

RESUMEN

The authors present an anesthesiologic technique, consisting of the use of propofol + fentanyl + O2. The main advantages, described in 82 neurosurgically treated patients, are the following: moderate decrease both of ICP and MAP, absence of frequency, modifications rapid recovery both of consciousness and of motility, which allows a preliminary valuation of neurological status.


Asunto(s)
Anestesia Intravenosa , Encéfalo/cirugía , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad
4.
Minerva Anestesiol ; 58(4 Suppl 1): 141-4, 1992 Apr.
Artículo en Italiano | MEDLINE | ID: mdl-1620436

RESUMEN

The authors report their experience on the use of urapidil in 31 patients, submitted to neurosurgical procedures. Urapidil, administered both in the inductive (0.7-1 mg/kg) and in preoperative phases (0.6-0.8 mg/kg/h), produced a MAP decrease of about 25% without significant variations in cardiac frequency or of other monitored parameters.


Asunto(s)
Encéfalo/cirugía , Hipotensión , Piperazinas , Adulto , Anciano , Femenino , Humanos , Hipotensión/prevención & control , Masculino , Persona de Mediana Edad
9.
Biomed Biochim Acta ; 43(4): 509-15, 1984.
Artículo en Inglés | MEDLINE | ID: mdl-6207813

RESUMEN

Spermidine (SPD) and spermine (SPM) produced in anaesthetized dogs significant cardiovascular changes at higher doses than other transmitters, i.e. l-noradrenaline, l-adrenaline, histamine, acetylcholine, which produce cardiovascular effects at doses of 0.01-0.05 micrograms/kg given intravenously. SPD was shown to be more active than SPM. The hypotensive response observed after i.v. injection is due to histamine release. The hypotensive and bradycardic effects observed after microinjection of SPD into III cerebral ventricle or into the vertebral artery and of SPM into the vertebral artery are due to an increase in parasympathetic output. Spermidine increased and spermine decreased the baroreceptor reactivity. SPD and SPM did not change the vascular beta- and alpha-adrenergic, cholinergic and histaminergic receptor reactivity.


Asunto(s)
Hemodinámica/efectos de los fármacos , Sistema Respiratorio/efectos de los fármacos , Espermidina/farmacología , Espermina/farmacología , Animales , Presión Sanguínea/efectos de los fármacos , Perros , Frecuencia Cardíaca/efectos de los fármacos , Liberación de Histamina/efectos de los fármacos , Masculino , Neurotransmisores/farmacología , Presorreceptores/efectos de los fármacos
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