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This study aimed to incorporate ß-AgVO3 and rGO into self-curing (SC) and heat-curing (HC) acrylic resins and to evaluate their physicochemical, mechanical, and antimicrobial properties while correlating them with the characterized material structure. Acrylic resin samples were prepared at 0 % (control), 0.5 %, 1 %, and 3 % for both nanoparticles. The microstructural characterization was assessed by scanning electron microscopy (SEM) (n = 1) and energy dispersive X-ray spectroscopy (EDS) (n = 1). The physicochemical and mechanical tests included flexural strength (n = 10), Knoop hardness (n = 10), roughness (n = 10), wettability (n = 10), sorption (n = 10), solubility (n = 10), porosity (n = 10), and color evaluation (n = 10). The microbiological evaluation was performed by counting colony-forming units (CFU/mL) and cell viability (n = 8). The results showed that the ß-AgVO3 samples showed lower counts of Candida albicans, Pseudomonas aeruginosa, and Streptococcus mutans due to their promising physicochemical properties. The mechanical properties were maintained with the addition of ß-AgVO3. The rGO samples showed higher counts of microorganisms due to the increase in physicochemical properties. It can be concluded that the incorporation of ß-AgVO3 into acrylic resins could be an alternative to improve the antimicrobial efficacy and performance of the material.
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OBJECTIVES: To incorporate the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) into denture base materials: heat-cured (HC) and 3D printed (3DP) resins, at concentrations of 2.5 %, 5 %, and 10 %; and to evaluate the antimicrobial activity in two multi-species biofilm: (1) Candida albicans, Candida glabrata, and Streptococcus mutans, (2) Candida albicans, Pseudomonas aeruginosa, and Staphylococcus aureus, and the wettability. METHODS: The AgVO3 was added to the HC powder, and printed samples were coated with 3DP with AgVO3 incorporated. After biofilm formation, the antimicrobial activity was evaluated by colony forming units per milliliter (CFU/mL), metabolic activity, and epifluorescence microscopy. Wettability was assessed by the contact angles with water and artificial saliva. RESULTS: In biofilm (1), HC-5 % and HC-10 % showed activity against S. mutans, HC-10 % against C. glabrata, and HC-10 % and 3DP-10 % had higher CFU/mL of C. albicans. 3DP-5 % had lower metabolic activity than the 3DP control. In biofilm (2), HC-10 % reduced S. aureus and P. aeruginosa, and HC-5 %, 3DP-2.5 %, and 3DP-5 % reduced S. aureus. 3DP incorporated with AgVO3, HC-5 %, and HC-10 % reduced biofilm (2) metabolic activity. 3DP-5 % and 3DP-10 % increased wettability with water and saliva. CONCLUSION: HC-10 % was effective against C. glabrata, S. mutans, P. aeruginosa, and S. aureus, and HC-5 % reduced S. mutans and S. aureus. For 3DP, 2.5 % and 5 % reduced S. aureus. The incorporation of AgVO3 into both resins reduced the metabolic activity of biofilms but had no effect on C. albicans. The wettability of the 3DP with water and saliva increased with the addition of AgVO3. CLINICAL SIGNIFICANCE: The incorporation of silver vanadate into the denture base materials provides antimicrobial efficacy and can prevent the aggravation of oral and systemic diseases. The incorporation of nanomaterials into printed resins is challenging and the coating is an alternative to obtain the inner denture base with antimicrobial effect.
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Biopelículas , Candida albicans , Bases para Dentadura , Nanopartículas del Metal , Pseudomonas aeruginosa , Plata , Staphylococcus aureus , Streptococcus mutans , Vanadatos , Humectabilidad , Biopelículas/efectos de los fármacos , Streptococcus mutans/efectos de los fármacos , Candida albicans/efectos de los fármacos , Staphylococcus aureus/efectos de los fármacos , Vanadatos/farmacología , Vanadatos/química , Pseudomonas aeruginosa/efectos de los fármacos , Plata/farmacología , Plata/química , Bases para Dentadura/microbiología , Nanopartículas del Metal/química , Antiinfecciosos/farmacología , Candida glabrata/efectos de los fármacos , Impresión Tridimensional , Ensayo de Materiales , Humanos , Nanoestructuras , Compuestos de Plata/farmacología , Compuestos de Plata/química , Materiales Dentales/química , Materiales Dentales/farmacologíaRESUMEN
Wear resistance is one of the properties that must be considered for maintaining the long-term functionality of artificial teeth in dental prostheses. This property can be altered by the method of tooth fabrication, the material, the chewing force, and the relationship to the antagonist tooth. This systematic review evaluated the wear resistance of artificial teeth obtained by the additive manufacturing method and aims to answer the question, "Do artificial teeth for dental prostheses obtained by additive manufacturing show wear resistance similar to prefabricated ones?" The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Checklist guidelines were followed with a customized search in Scopus, PubMed/Medline, Embase, Science Direct, and Google Scholar databases on August 30, 2023. The inclusion criteria were artificial teeth for dental prostheses in acrylic resin by additive manufacturing and comparing the wear resistance with conventional prefabricated teeth, in vitro and English studies, without time restriction. And excluded if 1) do not make artificial teeth by additive manufacturing or that were metal or ceramic teeth; 2) clinical trials, animal studies, review articles, case reports, letters to the editor, short communication, book chapters; 3) another language that is not English. The selection was in two steps, reading the titles and abstracts, followed by reading the selected studies in full. The risk of bias analysis was performed with the adaptation of the quasi-experimental studies tool by Joanna Briggs Institute. Four hundred and twelve articles were found in the databases, after the selection steps and application of eligibility criteria, 6 articles were included for qualitative data analysis and presented low risk of bias. For teeth obtained by additive manufacturing, 2 studies reported lower wear resistance, 2 studies had higher resistance, and 2 similar compared to prefabricated ones. Additive manufactured teeth compared to prefabricated teeth show influences on wear resistance due to differences in material composition, relationship to the antagonist's tooth, applied force, chewing cycles, and processing methods.
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STATEMENT OF PROBLEM: Knowledge of the effectiveness of hydroxyapatite coatings on the surface of titanium dental implants is lacking because of difficulties in standardizing their thickness, roughness, and effect on osseointegration. The selection of articles describing this coating in osseointegration will be of great relevance to implant dentistry. PURPOSE: This systematic review aimed to answer the question, "How effective is hydroxyapatite on titanium surfaces for osseointegration?" MATERIAL AND METHODS: The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines were followed, and the protocol was registered on the international prospective register of systematic reviews (PROSPERO) database (CRD42023422601). The PubMed, Scopus, Web of Science, and Embase databases were searched, and articles were selected manually in 2 steps by 2 blinded investigators according to the previously selected eligibility criteria. The risk of bias was assessed using the systematic review center for laboratory animal experimentation (SYRCLE) tool. RESULTS: Initially, 671 results were found. After analysis of eligibility criteria and full reading, 15 articles were included in the present review. Of these, 12 reported favorable osseointegration results for hydroxyapatite-coated surfaces, and 3 found no significant long-term difference between the coated and uncoated groups. CONCLUSIONS: Hydroxyapatite surface treatment is effective in the osseointegration of titanium dental implants because it favors the absorption of proteins, adhesion, and proliferation of bone cells when obtained by methods that ensure proper adhesion. (J Prosthet Dent xxxx;xxx:xxx-xxx).
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There is no consensus in the literature about the best non-cytotoxic antibacterial surface treatment for dental implants. Critically evaluate the existing literature and answer the question: "which surface treatment for dental implants made of titanium and its alloys has the greatest non-cytotoxic antibacterial activity for osteoblastic cells?" This systematic review was registered in the Open Science Framework (osf.io/8fq6p) and followed the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols. The search strategy was applied to four databases. Articles were selected that evaluated in both studies the properties of 1) antibacterial activity and 2) cytotoxicity on osteoblastic cells of titanium and their alloy dental implants when treated superficially. Systematic reviews, book chapters, observational studies, case reports, articles that studied non-dental implants, and articles that evaluated only the development of surface treatment were excluded. The Joanna Briggs Institute, a quasi-experimental study assessment tool, was adapted to assess the risk of bias. The search strategy found 1178 articles in the databases after removing duplicates in EndNote Web, resulting in 1011 articles to be evaluated by title and abstract, of which 21 were selected for full reading, of which 12 were included by eligibility criteria, and nine were excluded. Quantitative synthesis could not be performed due to the heterogeneity of the data (surface treatment, antibacterial assay, bacteria strain, cell viability assay, and cell type). Risk of bias assessment showed that ten studies were classified as low risk and two studies as moderate risk. The evaluated literature allowed us to conclude that: 1) The literature surveyed did not allow answering the question due to the heterogeneity of the studies; 2) Ten of the 12 studies evaluated presented surface treatments with non-cytotoxic antibacterial activity; 3) Adding nanomaterials, QPEI, BG, and CS, reduce the chances of bacterial resistance by controlling their adhesion by electrical forces.
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STATEMENT OF PROBLEM: Digital methods for manufacturing occlusal devices provide advantages over conventional techniques, but information about the mechanical properties of 3-dimensionally (3D) printed resins is scarce. PURPOSE: The purpose of this systematic review was to evaluate the literature to determine whether 3D-printed resins for occlusal devices present satisfactory mechanical performance when compared with milled and conventional heat polymerized and autopolymerized resins. MATERIAL AND METHODS: This systematic review followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol and was registered in the Open Science Framework. The search strategy was applied without restriction of time and language to Embase, PubMed, Scopus, Science Direct, and Web of Science databases, and to the nonpeer-reviewed literature in ProQuest and Google Scholar. The selection process was conducted independently in 2 stages by 2 reviewers according to the eligibility criteria. The risk of bias was analyzed by using a checklist of important parameters to be considered. The systematic review considered the population, intervention, comparison, outcome, studies (PICOS) format, where population was resins for 3D printing of occlusal devices, intervention was inherent characteristics of the resin, comparison was conventional heat polymerized, autopolymerized, and milled resins, outcome was mechanical performance, and studies were in vitro experimental studies. RESULTS: A total of 1430 articles were found with the search strategy. After removing 182 duplicates found in Rayyan, the title and abstract of 1248 articles were evaluated, of which 37 articles were screened from the databases, 23 were selected for full reading, and 6 met the eligibility criteria and were included in this review; 1 had a low risk of bias and 5 had a moderate risk. An additional search of the reference list of included articles did not result in the inclusion of any articles. A quantitative meta-analysis could not be performed because of the heterogeneity of the included studies regarding the type of resin used and the method for evaluating mechanical performance. CONCLUSIONS: Resins for 3D printing had satisfactory mechanical performance for interocclusal devices when compared with conventional heat polymerized and autopolymerized resins, except for hardness. Milled resins were better than 3D-printed resins in hardness, wear resistance, flexural strength, flexural modulus, and fracture resistance when printing angle and thickness were not considered. Further development is needed in terms of printing techniques and chemical composition, as they are important for optimal mechanical properties and clinical performance.
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Aim: The objective of this systematic review is to show the current state of the art on which type of attachment loses retention the most and has reduced durability and which factor causes these problems the most. Material and methods: This review followed the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) guidelines and it was registered with the Open Science Framework (OSF) (osf.io/2e3q5). The databases used for the electronic search of articles were Pubmed, Science Direct, Embase, and Scopus. Articles were selected by 2 independent reviewers according to the inclusion criteria. The risk of bias was analyzed by using the Joanna Briggs Institute (JBI) adapted quasi-experimental study evaluation tool. Results: The studies included in this review indicate that the use of cleansing solutions, high temperatures, and a more acidic pH decrease the durability of the attachments, mainly due to the loss of retention that occurs in different models and materials of the attachments, which requires their replacement in a shorter period. Conclusion: Of all the factors studied, the cleansing solutions proved to be the factor that most altered attachment retention. Different saliva compositions did not influence retention values. Aging changes retention values for attachments, mostly with loss of values.
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Background: This review aimed to identify antimicrobial agents incorporated into dental materials obtained through additive manufacturing and their efficacy. Methods: Protocol registration was performed in Open Science Framework (osf.io/sp3xa/) and an electronic search was carried out in the databases PubMed, Science Direct, Embase, Lilacs, and Scopus, up to February 2022, combining the terms ("additive manufacturing" OR "3D printing") AND (antimicrobial). Eligibility criteria included: experimental studies that incorporated 3D printing material with an antimicrobial agent for dental application; that evaluated antimicrobial activity; articles published in peer-reviewed journals and in English. Results: The database search resulted in 1139 references. The manual selection was carried out in 851 studies. Twenty-five articles were selected for full-text reading, of which 8 were included in this review. Polymers were the dental materials most often modified with antimicrobial agents for 3D printing, followed by metal alloy. The antimicrobials used were mainly nanoparticles, metal particles, antifungals, monomers containing quaternary ammonium salt, and antiseptics such as chlorhexidine. Conclusion: The addition of the antimicrobial agents in polymers and alloy for additive manufacturing showed promising efficacy against Candida spp., Gram-positive and Gram-negative bacteria.
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Objective: A critical analysis of the existing literature to answer "What is the influence of electrical charge of titanium alloys in the electrical interaction with osteoblastic cells for osseointegration?". Design: This systematic review followed PRISMA. The personalized search strategy was applied in PubMed, Science Direct, Embase, and Scopus databases, furthermore, in the grey literature in the Google Scholar and ProQuest. The selection process was carried out in two stages independently by two reviewers according to the eligibility criteria. The risk of bias was also analyzed. Results: When applying the search strategy, 306 articles were found, after removing duplicates 277 were analyzed by title and abstract, of which 33 were selected for full reading, of which 10 met the eligibility criteria. And one was included from the additional literature search. Of these, all had a low risk of bias. Conclusions: 1. The phenomenon of osseointegration is complex and, independent of the superficial electrical charge of the implant, it may occur. To understand osseointegration, attention must be paid to the synergistic action of the electrical potential; chemical composition, intrinsic to the alloy and from surface treatment; and topography, which will determine the speed of adhesion, proliferation, and osteoblast differentiation. 2. The presence of Ca2+ deposited on the surface acts as a driving force for biomineralization that induces osteoblastic attraction and differentiation; 3. For a better understanding of the current literature, more studies are needed to describe the osteogenic regulation process through protein mediation; 4. Topography and chemical composition act as decisive parameters for cell viability independent of the attractive electrical charge.
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Objective: Critically analyzed the existing literature to answer the question "What is the influence of roughness of surfaces for dental implants obtained by additive manufacturing compared to machined on osteoblastic cell adhesion and proliferation?" Design: This systematic review followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was registered in the Open Science Framework. The personalized search strategy was applied to Embase, Pub Med, Scopus, and Science Direct databases and Google Scholar and ProQuest grey literature. The selection process was carried out in two stages independently by two reviewers according to the eligibility criteria. The risk of bias was analyzed using a checklist of important parameters to be considered. Results: When applying the search strategy on databases 223 articles were found, after removing the duplicates, 171 were analyzed by title and abstract of which 25 were selected for full reading, of these, 6 met the eligibility criteria. 2 studies were included from the reference list totaling 8 articles included in this systematic review and none were included from the Grey Literature. 7 had a low risk of bias and 1 moderate. Conclusions: 1) Roughness is a property that must be analyzed and correlated with the chemical composition, intrinsic to the alloy and resulting from the surface treatment; morphology of topographic peaks and valleys; printing technique and its parameters; 2) Need for more studies on the biomolecular level to elucidate the mechanism by which the roughness and the morphology of topographical peaks and valleys descriptive of roughness influence osteoblastic adhesion and proliferation.
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STATEMENT OF PROBLEM: A consensus on the accuracy of additively manufactured casts in comparison with those fabricated by using conventional techniques for fixed dental prostheses is lacking. PURPOSE: The purpose of this systematic review was to determine the accuracy of additively manufactured casts for tooth- or implant-supported fixed dental prostheses in comparison with that of gypsum casts. MATERIAL AND METHODS: This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with the International Prospective Register of Systematic Reviews (PROSPERO) database (CDR42020161006). Eight databases were searched in December 2019 and updated in September 2020. Studies evaluating the dimensional accuracy of additively manufactured casts for fixed dental prostheses in comparison with that of gypsum casts were included. An adapted checklist for reporting in vitro studies (Checklist for Reporting In vitro Studies guidelines) was used to assess the risk of bias. RESULTS: Eight studies evaluating tooth-supported fixed dental prosthesis casts and 7 studies evaluating implant-supported fixed dental prosthesis casts were eligible for this review. Gypsum casts showed greater accuracy (trueness and precision) in most studies, although additively manufactured casts also yielded highly precise data. One study was associated with a low risk of bias, 9 with a moderate risk of bias, and 5 with a high risk of bias. CONCLUSIONS: In vitro studies showed that additively manufactured casts and gypsum casts share similar accuracy within the acceptable range for the fabrication of casts. The quality of scanned data, additive manufacture technology, printing settings, and postprocessing procedures plays an essential role in the accuracy of additively manufactured casts. Clinical studies are required to confirm these findings.
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Diseño Asistido por Computadora , Prostodoncia , Sulfato de Calcio , Técnica de Impresión Dental , Humanos , Impresión Tridimensional , Flujo de TrabajoRESUMEN
BACKGROUND: Auricular acupuncture (AA) is a complementary/integrative therapy, and can be used as adjuvant treatment in sleep disorders, anxiety and the painful symptomatology of temporomandibular disorders (TMDs). OBJECTIVE: The aim of this investigation was to evaluate the effectiveness of AA in reducing the symptoms of sleep disorders, anxiety and TMDs by applying the Fletcher and Luckett, Beck-BAI and RDC/TMD questionnaires: Axis II, respectively. DESIGN: This was a nonrandomized clinical trial in which AA was administered to patients between the ages of 20 and 45 years from the School of Dentistry at Ribeirão Preto, São Paolo, Brazil, who had at least one of the following: sleep disorder, anxiety or TMD. INTERVENTION: Mustard seeds were applied to predetermined auricular acupoints including: Shen Men, neurovegetative system (sympathetic), kidney, anxiety, stomach, maxilla and mandible, liver and stress, once a week for 8 weeks. OUTCOME MEASURES: To analyze the reduction in sleep disorder symptoms, we used the Fletcher and Luckett questionnaire; for anxiety symptoms, the Beck-BAI questionnaire, and for the degree of chronic TMD pain, the RDC/TMD (Axis II) questionnaire. RESULTS: Data on sleep, anxiety and TMD disorders were analyzed via Fisher's exact, Wilcoxon and Chi-Square non-parametric tests (α = 0.05), respectively. Reduction in sleep disorder symptoms after the proposed intervention was verified, showed a statistically significant difference (P = .014). There was a reduction in mean anxiety score and a decrease in painful TMD symptoms, but no significant difference (P = .50; P = .947, respectively) before and after AA. CONCLUSION: In our study, AA was effective in reducing sleep disorder symptoms and our data suggests some relief of symptoms of anxiety and TMD pain.
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Acupuntura Auricular , Trastornos del Sueño-Vigilia , Trastornos de la Articulación Temporomandibular , Adulto , Ansiedad/terapia , Trastornos de Ansiedad , Brasil , Depresión , Humanos , Masculino , Persona de Mediana Edad , Sueño , Trastornos del Sueño-Vigilia/terapia , Trastornos de la Articulación Temporomandibular/terapia , Adulto JovenRESUMEN
STATEMENT OF PROBLEM: A consensus on which dental implant alloy and surface treatment provide the best cell viability is unclear. PURPOSE: The purpose of this systematic review was to provide information on the influence of surface and intrinsic titanium alloy chemical components on cell viability. MATERIAL AND METHODS: The PubMed, LILACS, COCHRANE library, and Science Direct databases were electronically searched for the terms dental implants AND titanium AND cytotoxicity. Inclusion criteria were research articles that studied titanium or its alloys for chemical composition and cell viability and were published in English between 1999 and 2019. Articles that did not study titanium and its alloys, articles with nondental or biomedical implants, and articles that were not found in their entirety were excluded. RESULTS: A total of 1226 articles selected by title or abstract according to the inclusion and exclusion criteria resulted in 51 articles that were reduced to 27 after reading in full. The treatments analyzed were arc fusion, electron beam physical deposition, plasma electrolytic oxidation, coating addition, micro arc oxidation, anodization, thermochemical process, BMP-2 immobilization, pressure-assisted sintering, and alkali heat treatment. CONCLUSIONS: The evaluated literature did not allow a determination of the best surface treatment for cell viability because of the heterogeneity of the studies regarding the type of alloy, cell used in the MTT assay, study, and implant purpose (biomedical or dental). The cytotoxic effect of chemical components was dependent on dose, time, size, temperature, and cell type. The niobium, tantalum, zirconium, and molybdenum elements have been most often added in the development of less toxic Ti alloys with lower modulus of elasticity and increased strength.
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Implantes Dentales , Titanio , Aleaciones , Supervivencia Celular , Ensayo de Materiales , Propiedades de Superficie , CirconioRESUMEN
STATEMENT OF PROBLEM: Infection of a dental implant is undesirable and decreases the success rate of the dental prosthesis; however, systematic reviews on the issue are lacking. PURPOSE: The purpose of this systematic review was to evaluate studies that dealt with inherent factors or those applied to the titanium surface or alloys to provide an antimicrobial action. MATERIAL AND METHODS: SCOPUS, PubMed/Medline, Web of Science, EMBASE, and Science Direct databases were searched and manual searches made between June and July 2019 using the keywords "titanium," "surface," "implants," "photoelectron spectroscopy," and "fourier transform infrared spectroscopy." The criteria included in vitro studies evaluating the titanium surface and describing hydrophobicity, surface crystalline phase, nanotopography, surface charges, and their relationship with bacteria and/or osseointegration. RESULTS: A comprehensive search identified 767 articles that were selected by the title and/or abstract as per the inclusion criteria. Of the 58 studies selected for full reading, 7 were used for this systematic review. Another 6 studies were added by further research, resulting in 13 articles, all in vitro studies. As the selected studies had a high heterogeneity that precluded any statistical analysis of the data, a descriptive analysis of these topics was performed: hydrophilicity, surface crystalline phase, nanotopography, and surface charges. CONCLUSIONS: The articles analyzed in this systematic review suggest that hydrophilicity, crystalline phase, surface topography, and surface titanium charge, when altered, may provide an antimicrobial surface. However, the strategy used resulted in heterogeneous articles, making it impossible to demonstrate the unique effect of the electrostatic surface of titanium or titanium alloy used for implants and its effect on bacterial control.
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Implantes Dentales , Titanio , Adhesión Bacteriana , Oseointegración , Electricidad Estática , Propiedades de SuperficieRESUMEN
The incorporation of nanoparticles into endodontic sealers aims at increasing antimicrobial activity of the original material. Aim. The aim of this study is to incorporate the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3, at 2.5%, 5%, and 10%) into three endodontic sealers and evaluate the antibacterial activity of freshly sealers, surface topography and chemical composition, and setting time. Material and Methods. The AgVO3 was incorporated into AH Plus, Sealer 26, and Endomethasone N at concentrations 0%, 2.5%, 5%, and 10% (in mass). The antibacterial activity of freshly sealers was assessed by direct contact with Enterococcus faecalis and CFU/mL count (n=10), surface topography, and chemical composition were measured by SEM/EDS, and the setting time was measured by Gillmore needle (n=10). The Kruskal-Wallis and Dunn statistical tests were applied (α=0.05). Results. All groups of sealers evaluated inhibited E. faecalis (p>0.05). The incorporation of AgVO3 altered the atomic proportions between components of the endodontic sealers, and the percentage of silver (Ag) and vanadium (V) increased proportionally to the concentrations of AgVO3. Topography analysis showed differences in components distribution on the surface of the specimens. The sealers incorporated with AgVO3 of AH Plus presented a lower setting time than the control group (p<0.05). For Sealer 26 and Endomethasone N, the incorporation of AgVO3 increased the setting time in relation to control group (p<0.05). Conclusions. The modification of endodontic sealers by AgVO3 increased the atomic percentage of Ag and V proportionally to the concentration of the nanomaterial and changed the atomic percentage of the sealer components and setting times. It cannot be affirmed that the AgVO3 promote differences in the antimicrobial activity of freshly sealers, and further investigations of the antimicrobial activity of the set sealers should be carried out.
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Antibacterianos , Bismuto , Hidróxido de Calcio , Enterococcus faecalis/crecimiento & desarrollo , Nanoestructuras/química , Materiales de Obturación del Conducto Radicular , Compuestos de Plata , Vanadatos , Antibacterianos/farmacología , Bismuto/química , Bismuto/farmacología , Hidróxido de Calcio/química , Hidróxido de Calcio/farmacología , Dexametasona/química , Dexametasona/farmacología , Combinación de Medicamentos , Formaldehído/química , Formaldehído/farmacología , Humanos , Hidrocortisona/química , Hidrocortisona/farmacología , Materiales de Obturación del Conducto Radicular/química , Materiales de Obturación del Conducto Radicular/farmacología , Compuestos de Plata/química , Compuestos de Plata/farmacología , Timol/análogos & derivados , Timol/química , Timol/farmacología , Vanadatos/química , Vanadatos/farmacologíaRESUMEN
Introduction: The aim of this study was adding the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) (0, 2.5, 5, and 10%) to the endodontic sealers AH-Plus, Sealer 26 and Endomethasone N, and evaluate the antimicrobial activity, solubility and pH. Methods and Materials: The antimicrobial activity of freshly mixed sealers (n=10) and set sealers (n=9) against Enterococcus faecalis (E. faecalis) was evaluated by colony forming units per milliliter and epifluorescence microscopy. Solubility (n=9) and pH (n=10), 6 and 24 h and 7, 14, and 30 days were also evaluated. The Kruskal-Wallis and Dunn's post-test were applied for the antimicrobial activity of fresh sealers. ANOVA and Tukey's post-test was used for set sealers and solubility, and Friedman's two-way analysis of variance for pH (α=0.05). Results: The fresh sealers inhibited E. faecalis. Set Sealer 26 (5 and 10% AgVO3) and Endomethasone N (2.5, 5, and 10% AgVO3) presented higher activity then the corresponding controls. Modification with AgVO3 did not influence the solubility of AH Plus and Sealer 26, but Endomethasone N (5%) presented reduced solubility. The AH-Plus groups showed acidic pH, and Sealer 26, basic pH after 30 days. Endomethasone N (5 and 10% AgVO3) presented statistical difference compared to 0% (P<0.05). Conclusion: In this in vitro study all fresh sealers and set Sealer 26 (5 and 10%) and Endomethasone N (2.5, 5, and 10%) presented higher antimicrobial activity than controls. The modification with 5% and 10% AgVO3 decreased solubility and pH of Endomethasone N, but did not affect the other groups.
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La limpieza del sistema de conductos radiculares constituye uno de los principales fac-tores para determinar el éxito del tratamiento endodóntico. Por lo tanto, la irrigación complementaria a la instrumentación juega un papel fundamental en la eliminación de las bacterias, restos de dentina y materiales terapéuticos. Además, el método de irrigación es fundamental para garantizar la eficiencia en la limpieza del sistema de conductos ra-diculares, que puede realizarse manualmente con una jeringa y una aguja, también utili-zando dispositivos específicos para esta finalidad, como el ultrasonido. El objetivo de este estudio fue realizar una revisión de literatura sobre el efecto del ultrasonido en la limpieza del sistema de conductos radiculares. Una búsqueda eletrónica fue realizada en las bases de datos PubMed, LILACS y Cochrane Library, con los términos: "passive ultrasonic irri-gation", "root canal" y "endodontic irrigation". Los artículos fueron seleccionados a partir de los criterios de inclusión y exclusión. Se concluyó que la irrigación ultrasónica pasiva es eficaz en relación a la eliminación de bacterias, hidróxido de calcio, restos dentinarios y smear layer, utilizándose hipoclorito de sodio (NaOCl) como solución de irrigación, permitiendo así una optimización en la limpieza del sistema de conductos radiculares. Palabras clave: Endodoncia; Ultrasonido; Irrigación; Descontaminación (fuente: DeCS BIREME).
The cleaning of root canal system is one of the principal factors in determining the suc-cess of endodontic treatment. Thus, complementary irrigation to the instrumentation plays a fundamental role in the removal of bacteria, dentin remains and therapeutic ma-terials. In addition, the irrigation method is primordial to ensure the cleaning efficiency of the root canal system; it can be performed manually by syringe and needle, but also by using specific devices for this purpose, such as ultrasound. The objective of this study was to perform a review of the literature on the effect of ultrasound on the cleaning of root canal system. An electronic search was performed in the PubMed, LILACS and Cochrane Library databases, with the terms "passive ultrasonic irrigation", "root canal" and "endodontic irrigation". Articles were selected based on the inclusion and exclusion criteria. It was concluded that passive ultrasonic irrigation is effective as the elimination of bacteria, calcium hydroxide, dentin debris and smear layer, using sodium hypochlorite (NaOCl) as an irrigating solution, thus allowing an optimization in the cleaning of root canal system. Keywords: Endodontics; Ultrasonics; Irrigation; Decontamination (source: MeSH NLM).
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Objetivo: Avaliar o comportamento mecânico de im-plantes odontológicos submetidos à torção manual, a fim de analisar o ponto de ruptura e determinar a região mais frágil e susceptível à deformação, por meio de mi-croscopia eletrônica de varredura, antes e após a reali-zação do ensaio de torção. Materiais e método: Foram selecionados quatro modelos de implantes da marca Co-nexão® (n=5): Master Screw, Porous, Conect AR e Conect Cônico. Foi utilizado um torquímetro digital para a apli-cação de torque e com um microscópio eletrônico de varredura avaliou-se a superfície dos implantes antes e após o ensaio de torção. Resultados: Os resultados foram obtidos pela análise estatística ANOVA (P < 0,05), segui-do do teste de Tukey (P < 0,05). Após a torção verificou--se que as quatro amostras de implantes apresentaram diferentes médias para a variável força máxima, porém, sem diferença estatística significante para os implantes Master Screw, Porous e Conect AR (p > 0,05), sendo ape-nas o implante Conect Cônico estatisticamente diferente (p < 0,05). Quanto às imagens obtidas a partir da análise ao MEV observou-se fratura do montador dos implantes Master Screw e Porous, ruptura dos implantes Conect AR, e espanamento das roscas internas dos Cônicos. Conclusão: Os modelos de implantes testados apresen-taram diferentes comportamentos mecânicos quando submetidos à aplicação de forças, com os Cônicos apre-sentando menor resistência ao ensaio de torção.
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El objetivo de este trabajo fue verificar la influencia del Envejecimiento Artificial Acelerado sobre la resistencia a compresión de tres resinas compuestas. Los especimenes fueron confeccionados con auxilio de una matriz de nylon utilizando la técnica incremental, en cuanto a la manipulación se siguieron las instrucciones del fabricante , en total fueron confeccionados 48 especimenes utilizando las resina compuestas Filtek Supreme (3M-ESPE), Charisma (Heraeus-Kulzer) e Filtek Z-250 (3M-ESPE). Transcurridas 24 horas, 24 especimenes, 8 de cada material, fueron sometidos a ensayos mecánicos de compresión en la Máquina Universal de Ensayos (EMIC DL-2000) con una célula de carga de 2000Kgf y velocidad de 0,05mm/min. Los otros 24 cuerpos de prueba fueron sometidos a envejecimiento artificial acelerado en la máquina de C-UV Sistema Acelerado de Envejecimiento para no metálicos - ASTM-G-53 por 192 horas, lo que equivale a aproximadamente 5 años de envejecimiento en condiciones clínicas normales, posteriormente sometidas a ensayos mecánicos de compresión. Se realizo el análisis estadístico comparativo entre los resultados obtenidos utilizando el test de ANOVA/Tukey (P<0,05) y fue verificado que no hubo diferencia estadística en la resistencia a compresión entre las resinas Z-250 y Filtek Supreme envejecidas y no envejecidas. Entretanto se presento diferencia estadística entre las muestras confeccionadas con la resina Charisma envejecida y no envejecida
The objective of this work was to verify the influence of the Sped up Artificial Aging in the compressive strength of 3 composed resins. It was used a matrix of nylon for confection of 48 bodies of test with 8,0mm of height and 4,0mm of width, having been 16 with the Filtek resin Supreme(3M), 16 with Charisma (Heraeus Kulzer) and 16 with Filtek Z-250(3M). For the confection of the test bodies the incremental technique was used respecting the time of curing indicated for the manufacturers. Passed 24 hours, half of the bodies of test of each material was submitted to the compressive assay in the Universal Machine of Assays (EMIC DL-2000) with load cell of 2000Kgf and speed of 0,05mm/min. To another half it was submitted to the artificial aging sped up in the C-UV machine Sped up System of Aging for not metallic - ASTM-G-53 for 192 hours that is equivalent approximately the 5 years of aging and later submitted to the compressive assay. Analysis was become fullfilled comparative statistics between the gotten results using ANOVA/Tukey (P<0.05). It was verified that it did not have difference statistics in the compressive strength between the resins aged and not aged Z-250 and Filtek Supreme. However difference occurred statistics between aged and not aged the Charisma resin