Asunto(s)
Células Epiteliales , Citoesqueleto de Actina/ultraestructura , Animales , Mama/citología , Gatos , Recuento de Células , Diferenciación Celular , Epitelio/fisiología , Femenino , Fibroblastos/citología , Glucógeno/metabolismo , Histocitoquímica , Humanos , Lactancia , Masculino , Glándulas Mamarias Animales/citología , Ciclo Menstrual , Microscopía Electrónica , Mioepitelioma/metabolismo , Mioepitelioma/patología , Organoides/ultraestructura , Oxidorreductasas/metabolismo , Embarazo , Alveolos Pulmonares/citología , Ratas , Receptores Adrenérgicos alfa/fisiología , Glándulas Salivales/citología , SalivaciónRESUMEN
Analysis of the fine structure of glandular-solid tumors of the ovaries of endometrioid and serous genesis was carried out for specification of criteria for differential diagnosis of these tumors. The specific ultrastructural features (homogeneous or heterogeneous cell composition, the presence or absence of villi, tonofibrilos, glycogen inclusions) were shown to be present in areas of formation of glandular structures. Diagnosis of solid variants of endometrioid and serous carcinomas should also take into consideration the rate of occurrence of such ultrastructural signs typical of malignant cells as deep invaginations of the nuclear membrane, extended perinuclear space, increased number of nucleoli and macrosegregation of their content, increased number of myelin figures, polymorphism of mitochondria, cut-up cellular surface, well-developed laminar complex, and hypertrophy of the cytoplasmic reticulum. In serous carcinomas these features occur much more frequently.
Asunto(s)
Adenocarcinoma/ultraestructura , Cistadenocarcinoma/ultraestructura , Endometriosis/ultraestructura , Neoplasias Ováricas/ultraestructura , Femenino , Humanos , Microscopía ElectrónicaRESUMEN
Electron-microscopy was used to study the intraoperative material in 37 patients with serous (24), mucinous (8) and endometroid (5) ovarian neoplasms of benign, boundary and malignant forms. It was shown that the polysome-lamellae complexes are characteristic only of the carcinoma epithelium and practically are observed neither in benign nor in boundary analogs. This may serve an additional criterion of a malignant nature of neoplasms at the ultrastructural level. Taking into account the architectonics 3 variants of the polysome-lamellae complexes should be distinguished: polysome-lamellae, lamellae and lattice structures. All these variants may be encountered in one and the same tumor.
Asunto(s)
Organoides/ultraestructura , Neoplasias Ováricas/ultraestructura , Polirribosomas/ultraestructura , Adenocarcinoma/ultraestructura , Adenocarcinoma Mucinoso/ultraestructura , Endometriosis/ultraestructura , Epitelio/ultraestructura , Femenino , Humanos , Microscopía ElectrónicaRESUMEN
Using electron microscopy the authors have studied the operation material of 15 patients with serous (9 cases) and endometrioid (6 cases) ovarian neoplasms. It was demonstrated that the epithelium of endometrioid neoplasms differs from that of serous ones by less polymorphism, the absence of cilia, the signs of secretory activity and more intense development of tonofibrils in the cytoplasm.
Asunto(s)
Endometriosis/ultraestructura , Neoplasias Ováricas/ultraestructura , Adenocarcinoma/ultraestructura , Femenino , Humanos , Microscopía Electrónica , Quistes Ováricos/ultraestructuraRESUMEN
Use of the complex of morphological methods (histological, morphometric, electron microscopy and tissue culture technic) in examining the operation material enabled a more precise and full idea to be formulated of the principal stages of the morphogenesis of serous ovarian cystomas and also allowed the validation of their differentiation between benign, boundary (intermediate) and malignant types.