RESUMEN
On the basis of positive skin snips for Onchocerca cervicalis microfilariae (MF), 45 horses were chosen from 48 in a total of 257 screened on 12 locations in the northeast Province of Formosa (Argentina), and randomly assigned to two treatment groups of 20 horses each, and a nontreated control group of five horses. On Day 14 post-treatment (PT), skin snip samples in the ivermectin-treated (0.2 mg/kg) group were negative for normal viable microfilariae (MF), while horses in the control group maintained their pretreatment level of infection. On the same Day in the moxidectin-treated (0.4 mg/kg) group, 18 horses were negative for MF, but the remaining two had a total of 1 and 2 MF, respectively (equivalent to 10 and 20 MF/g of skin), but all three parasites showed marked cuticular and structural damage. Both horses were negative in a repeat biopsy on Day 21. From Day 3 PT, one ivermectin-treated horse (5%) evidenced an approximate 15 x 2 x 3 cm-sized, apparently nonpainful, oedematous swelling on the ventral midline, 20 cm in front of the navel, which remained unchanged on Day 14 PT. Adverse reactions were not observed in the moxidectin-treated group. Parasitaemia was found in 18.7% of sampled horses (48 of 257), and the number of MF varied between 10-1820/g of skin snip (mean 172). Similar prevalence and total counts had been described previously in 1985 and 1986 in cattle-farm horses in the same area of Argentina; in surveys in Texas (1974) and Louisiana (1995) in the USA, infection rates were also similar, but total counts much higher. It is concluded that moxidectin 2% equine oral gel and ivermectin 2% equine oral paste, were equally 100% effective in the control of O. cervicalis MF. Contrary to ivermectin, moxidectin did not cause post-treatment dermal reactions.
Asunto(s)
Antihelmínticos/uso terapéutico , Enfermedades de los Caballos/tratamiento farmacológico , Ivermectina/uso terapéutico , Oncocercosis/veterinaria , Administración Oral , Animales , Antihelmínticos/administración & dosificación , Antibacterianos , Argentina , Femenino , Geles , Enfermedades de los Caballos/parasitología , Caballos , Ivermectina/administración & dosificación , Macrólidos/administración & dosificación , Macrólidos/uso terapéutico , Masculino , Pomadas , Onchocerca/aislamiento & purificación , Oncocercosis/tratamiento farmacológico , Piel/parasitologíaRESUMEN
During the rainy season in the central valley of Cochahbamba, Bolivia, the larvae and nymphae of this tick were found feeding under the tails of dairy cattle as well as in their ears. The conditions that apparently favour the temporary infestation of this site on some cows are discussed briefly.
Asunto(s)
Enfermedades de los Bovinos/parasitología , Bovinos/parasitología , Infestaciones por Garrapatas/veterinaria , Animales , Larva , Ninfa , Infestaciones por Garrapatas/parasitologíaRESUMEN
An outbreak of tropical theileriosis (T. annulata infection) is reported in artificial insemination Holstein bulls in Kabul (Afghanistan). The diagnostic work at the Central Veterinary Diagnostic Laboratory is described and the treatment given and results obtained by the Kabul Animal Health Clinic are reported. This case report constitutes the first account of the disease in Afghanistan where diagnostic confirmation has been made from material sent to internatinational reference centres.