RESUMEN
Induction motor driven pumps are a staple in many sectors of industry, and crucial equipment in naval ships. Such machines can suffer from a wide variety of issues, which may cause it to not perform its function. This can either be due to degradation of components over time, or due to incorrect installation or usage. Unexpected failure of the machine causes downtime and lowers the availability. In some cases, it can even lead to collateral damage. To prevent collateral damage and optimise the availability, many asset owners apply condition monitoring, measuring the dynamic response of the system while in operation. Two high-frequency measurement methods are widely accepted for the detection of faults in rotating machinery at an early stage: vibration measurements, and motor current and voltage measurements. These methods can also distinguish between different failure mechanisms and severities. The dataset described in this article presents experimental data of two centrifugal pumps, driven by induction motors through a variable frequency drive. Besides measurements of behaviour that is considered healthy (new bearings, well aligned), the machines have also been subjected to a variety of (simulated) faults. These faults include bearing defects, loose foot, impeller damage, stator winding short, broken rotor bar, soft foot, misalignment, unbalance, coupling degradation, cavitation and bent shaft. Most faults were implemented at multiple levels of severity for multiple motor speeds. Both vibration measurements, and current and voltage measurements were recorded for all cases. The dataset holds value for a wide range of engineers and researchers working on the development and validation of methods for damage detection, identification and diagnostics. Due to the extensive documentation of the presented data, labelling of the data is close to perfect, which makes the data particularly suitable for developing and training machine learning and other AI algorithms.
RESUMEN
BACKGROUND: Palliative sedation is the widely-used intervention of administering sedating agents to induce a state of unconsciousness to take away a dying patient's perception of otherwise irrelievable symptoms. However, it remains questionable whether this ethically complex intervention is beneficial for patients and whether the associated lack of communication in the last phase of life has a negative impact on relatives' wellbeing. METHODS: An observational questionnaire study was conducted among relatives of a consecutive sample of patients who died a non-sudden death in the Erasmus MC Cancer Institute or in the hospice 'Laurens Cadenza' (both in Rotterdam) between 2010 and 2013. RESULTS: Relatives filled in questionnaires regarding 151 patients who had been sedated and 90 patients who had not been sedated. The median time since all patients had passed away was 21 (IQR 14-32) months. No significant differences were found in relatives´ assessments of the quality of end-of-life care, patients´ quality of life in the last week before death and their quality of dying, between patients who did and did not receive sedation, or in relatives' satisfaction with their own life, their general health and their mental wellbeing after the patient's death. CONCLUSIONS: The use of sedation in these patients appears to have no negative effect on bereaved relatives' evaluation of the patient's dying phase, or on their own wellbeing after the patient's death.
Asunto(s)
Cuidados Paliativos/métodos , Cuidado Terminal/métodos , Anciano , Anciano de 80 o más Años , Aflicción , Femenino , Humanos , Masculino , Persona de Mediana Edad , Calidad de Vida , Encuestas y CuestionariosRESUMEN
PURPOSE: The purpose of the study was to explore relatives' descriptions and experiences of continuous sedation in end-of-life care for cancer patients and to identify and explain differences between respondents from the Netherlands, Belgium, and the UK. METHODS: In-depth interviews were held between January 2011 and May 2012 with 38 relatives of 32 cancer patients who received continuous sedation until death in hospitals, the community, and hospices/palliative care units. RESULTS: Relatives' descriptions of the practice referred to the outcome, to practical aspects, and to the goals of sedation. While most relatives believed sedation had contributed to a 'good death' for the patient, yet many expressed concerns. These related to anxieties about the patient's wellbeing, their own wellbeing, and questions about whether continuous sedation had shortened the patient's life (mostly UK), or whether an alternative approach would have been better. Such concerns seemed to have been prompted by relatives witnessing unexpected events such as the patient coming to awareness during sedation. In the Netherlands and in Belgium, several relatives reported that the start of the sedation allowed for a planned moment of 'saying goodbye'. In contrast, UK relatives discerned neither an explicit point at which sedation was started nor a specific moment of farewell. CONCLUSIONS: Relatives believed that sedation contributed to the patient having a good death. Nevertheless, they also expressed concerns that may have been provoked by unexpected events for which they were unprepared. There seems to exist differences in the process of saying goodbye between the NL/BE and the UK.
Asunto(s)
Sedación Consciente , Familia/psicología , Neoplasias , Cuidados Paliativos , Cuidado Terminal , Adulto , Anciano , Anciano de 80 o más Años , Bélgica , Aflicción , Sedación Consciente/métodos , Sedación Consciente/psicología , Comparación Transcultural , Toma de Decisiones , Etnopsicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neoplasias/psicología , Neoplasias/terapia , Países Bajos , Cuidados Paliativos/métodos , Cuidados Paliativos/psicología , Investigación Cualitativa , Cuidado Terminal/métodos , Cuidado Terminal/psicología , Reino UnidoRESUMEN
BACKGROUND: The concentration of nitric oxide (NO) measured from the nose is much higher than in the lower airways and increases during humming. We assessed nasal NO (nNO) normal values during breath hold and during humming in healthy adults. MATERIALS AND METHODS: Nasal NO concentrations were measured in healthy adults (ages 18-70). They held their breath for 10 s and thereafter hummed as loud as possible with their mouths closed also for 10 s. During breath hold, air was passively extracted from one nostril with 700 mL min(-1). The average NO concentration at the plateau after 7-10 s was recorded and the mean of three consecutive measurements was calculated. During humming, air was extracted with 1200 mL min(-1), the peak NO values were recorded. RESULTS: One hundred healthy adults participated (37 men). The nNO concentrations during breath hold were distributed normally (mean: 455 parts per billion (p.p.b.), SD 147). A random subgroup of 40 out of the 100 subjects (15 men) performed nNO measurement during humming. The median peak NO value was 1019 p.p.b. (SD 561) at the first, and 837 p.p.b. (SD 408) at the second measurement. There was a significant difference between the peak NO values of first and second humming. CONCLUSION: We present normal values for nNO in adults, which can be used to assess the value of nNO in respiratory illnesses. The peak nNO values during humming are variable, and their clinical relevance remains to be shown.