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AIM: This study aimed to investigate the associations between upper- and lower-limb muscle strength, mass, and quality and health-related quality of life (HRQoL) among community-dwelling older adults. METHODS: A cross-sectional study was conducted with 428 Brazilian community-dwelling older adults aged 60 to 80 years. Upper- and lower-limb muscle strength were evaluated through the handgrip strength (HGS) test and the 30-s chair stand test, respectively. Muscle mass was assessed by dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA). Muscle quality was evaluated using the muscle quality index (MQI). HRQoL was assessed using the World Health Organization Quality of Life Brief Version questionnaire. RESULTS: Lower-limb, but not upper-limb, muscle strength and quality were independently associated with HRQoL, particularly within the domains of physical capacity, environment, and overall HRQoL for both males and females (P < 0.05). DXA- and BIA-derived analyses provided similar results in relation to muscle mass and muscle quality. CONCLUSIONS: Lower-limb, but not upper-limb, muscle strength and quality were independently associated with HRQoL among community-dwelling older adults. Moreover, the results obtained from both BIA and DXA were similar, highlighting that BIA can serve as a viable surrogate method for estimating body composition in resource-limited clinical settings. Geriatr Gerontol Int 2024; 24: 683-692.

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Dual-process theories postulate that both reflective and automatic processes regulate health behavior. Further research is required to test the basic postulates of dual-process theories. We investigated the direct associations and moderating effect between automatic processes and multiple indicators of reflective processes on various levels of physical activity and sedentary behavior assessed using accelerometry in adults who were not participating in regular physical exercise programs. This cross-sectional study included 257 adults. Each participant completed a computerized test for automatic associations, a set of questions assessing reflective processes, a seven-day assessment using accelerometers to determine their levels of physical activity and sedentary behavior. The results showed a direct relationship between perceived benefits (B = 15.90, p = 0.043), perceived cons (B = -12.81, p = 0.034), decisional intention (B = -0.07, p = 0.049) with light physical activity, and self-efficacy with daily steps (B = 485.71, p = 0.008). There was a positive association between intention strength and daily steps when implicit associations favored physical activity (b = 623.36, LLCI = 79.09, ULCI = 1167.62, p = 0.025); a negative association between self-efficacy and sedentary behavior when implicit associations favored sedentary behavior (b = -25.73, LLCI = -49.77, ULCI = -1.70, p = 0.035); and a positive association between intention strength and sedentary behavior when implicit associations favored physical activity (b = 34.18, LLCI = 8.81, ULCI = 59.56, p = 0.008). These findings underscore the importance of considering the interplay between reflective and automatic processes in shaping movement behavior.

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PURPOSE: Arterial stiffness is a subclinical marker of cardiovascular disease (CVD). The pre-frailty phenotype is associated with a higher risk for CVD. This study investigated the association between the pre-frailty phenotype and arterial stiffness in community-dwelling older adults without diagnosed CVD. METHODS: In total, 249 community-dwelling older adults aged 60-80 years were included in this cross-sectional study. The pre-frailty phenotype was defined by the standardized Fried criteria (muscle weakness; slow walking speed; low physical activity; unintentional weight loss; self-reported exhaustion). Participants with one or two standardized Fried criteria were classified as pre-frail and those with zero criteria as robust. Arterial stiffness was measured by aortic pulse wave velocity (aPWV). The data were analyzed using the generalized linear model. RESULTS: From 249 participants (66.1 ± 5.3 years; 79.5% females), 61.8% (n = 154) were pre-frail and 38.2% (n = 95) robust. Pre-frail older adults had a higher aPWV (ß = 0.19 m/s; p = 0.007) compared to their robust peers. CONCLUSIONS: The pre-frailty phenotype was associated with higher arterial stiffness in community-dwelling older adults aged 60-80 years. Pre-frail older adults may have a higher risk for CVD.

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OBJECTIVE: To investigate the moderating effect of step count and peak cadence on the relationship of sedentary time and cardiometabolic disease risk in community-dwelling older adults. METHODS: This cross-sectional study included 248 older adults aged 60-80 years without cardiovascular disease (66.0 ± 4.6 years of age; 78 % females). Sedentary time, step count and peak cadence were measured by a hip-worn accelerometer for seven days. Peak cadence was defined as the average of 30 min of the day (but not necessarily consecutive) with the highest cadence (steps per minute) for all valid days. Cardiometabolic disease risk was defined using a sex-specific continuous metabolic syndrome score (cMetS). Sedentary time was used as an explanatory variable for cMetS and step count and peak cadence as moderators. The analyses were adjusted for known cardiometabolic disease risk factors and accelerometer wear time. The Johnson-Neyman technique was used to specify the value of moderator variables at which the significant relationship between sedentary time and cMetS disappears. RESULTS: Both step count (ß = -0.186, P = 0.032) and peak cadence (ß = -0.003, P = 0.007) showed a moderating effect on the relationship of sedentary time and cMetS. The association of sedentary time and cMetS was not statistically significant (p > 0.05) when step count or peak cadence exceed 5715 steps per day and 57 steps per minute, respectively. CONCLUSION: Steps per day and peak cadence moderate the association of sedentary time and cardiometabolic disease risk in older adults. Therefore, steps per day and peak cadence seem to offset the deleterious effects of sedentary time on cardiometabolic health in this population.

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To investigate the joint associations of accelerometer-measured moderate-vigorous physical activity (MVPA) and sedentary time (ST) with cardiometabolic risk in older adults. This cross-sectional study included 248 participants (aged 65.8 ± 5.1 years; 73.7% females). Cardiometabolic risk was defined using continuous metabolic syndrome score (cMetS). MVPA and ST were assessed by accelerometry. Participants were categorized according to their MVPA and ST levels: i) 'Inactive + High ST' (<150 min/week and > 10.6 h/day); ii) 'Inactive + Low ST' (< 150 min/week and ≤ 10.6 h/day); iii) 'Active + High ST' (≥ 150 min/week and > 10.6 h/day) and iv) 'Active + Low ST' (≥ 150 min/week and ≤ 10.6 h/day). The cut-offs for active and inactive were based on current PA guidelines. The cut-offs for low and high ST were based on the median value from this cohort. Generalized linear models were used for data analyses ('Inactive + High ST' as group reference) controlling for known cardiometabolic risk factors. The 'Active + Low ST' (ß = -0.34, 95% CI -0.57, -0.11) and 'Active + High ST' (ß = -0.28, 95% CI -0.55, -0.02) groups had lower cMetS compared to the 'Inactive + High ST' group (p < 0.05). No difference was found between the 'Inactive + Low ST' and 'Inactive + High ST' groups (ß = -0.19, 95% CI -0.41, 0.03). Meeting MVPA recommendations (≥ 150 min/week) is associated with a lower cardiometabolic risk in older adults, even in those with high ST.

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The objective of this study was to investigate the association between cardiorespiratory fitness (CRF) and performance in multiple domains of executive functions in school-aged adolescents. A sample of 132 adolescents (43% girls) aged 11-16 years were included in this cross-sectional study. Each participant completed a progressive aerobic cardiovascular endurance running (PACER) test, computerized cognitive tasks (Attentional Network, Berg's Card Sorting, Go/No-Go oddball, Sternberg's Working Memory, and Tower of London) and questionnaire for daytime sleepiness, as well as other factors that might influence cognitive performance (age, sex, school year, pubertal stage, and body mass index - BMI). Generalized linear model was used to calculate the coefficient estimates (ß) and its 95% confidence interval (CI) for the cognitive tasks using PACER laps as a predictor, controlling for potential confounding variables. There was a negatively association of PACER laps with planning (ß = -17.1, 95% CI -31.9, -2.3) and solution (ß = -44.6, 95% CI -75.1, -14.2) time in performing the Tower of London task, as well as with perseverative errors in performing Berg's task (ß = -0.073, 95% CI -0.133, -0.013). Moderating effect of sex was found for the association of PACER laps with completed categories and perseverative errors in Berg's task (p < 0.05). Mediating effect of BMI was found for the association between PACER laps and NoGo task, revealing a full mediator accounted for 81% of the total effect mediated (standardized indirect effect, -0.069, 95% CI -0.140, -0.020; standardized direct effect, 0.011, 95% CI -0.149, 0.165). No association was found for Attentional or Sternberg's tasks. The findings suggest that school-aged adolescents with higher CRF level showed better planning and problem-solving abilities and cognitive flexibility. Additionally, the positive association of CRF with cognitive flexibility was sex-moderated and with inhibitory control was BMI-mediated.

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We investigated the acute effects of isometric biceps exercise on resting and ambulatory blood pressure in hypertensive adults. A total of 12 medicated hypertensive adults (aged 47±7 years; body mass index 27.2±2.7 kg/m2; resting blood pressure 123±12/74±6 mmHg) performed an isometric biceps exercise session (bilateral biceps exercise; 4×1 min at 30% of 1-RM, 2 min recovery) and a control session (without exercise) in a randomized order separated by a 7 to 10-day period. Resting blood pressure, heart rate, and heart rate variability indexes (SDNN, RMSSD, LF, HF, and LF/HF) were measured pre- and up to 30 min post-sessions. Next, ambulatory blood pressure was monitored during 22-hour post-sessions (awake and asleep periods). No significant changes were observed for resting blood pressure, heart rate, or heart rate variability indexes up to 30 min post-sessions (p>0.05). Furthermore, no significant differences were observed in average ambulatory blood pressure values in 22-hour (126±11/71±6 mmHg vs. 126±15/71±9 mmHg), awake (127±10/74±6 mmHg vs. 130±14/75±10 mmHg), and asleep (123±15/68±6 mmHg vs. 120±17/66±9 mmHg) periods between the control and isometric sessions, respectively (p>0.05). In conclusion, an isometric biceps exercise session does not elicit an acute antihypertensive effect in adults with hypertension, which suggests that its prescription to improve the acute BP control is limited.

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ABSTRACT Objective: This study investigated the acute effects of high-intensity interval (HIIE) and moderate-intensity continuous (MICE) exercise on ghrelin levels in obese men. Subjects and methods: A total of 10 obese men (age 27.6 ± 1.8 years, body mass index 35.4 ± 4.5 kg/m², body fat 39.9 ± 2.1%) performed two exercise sessions in a randomized order: HIIE (10 × 1 min intervals at 90% of the maximal heart rate [HRmax] interspersed by 1 min of active recovery) and MICE (20 min at 70% of the HRmax). Ghrelin levels were assessed pre-, post- and 1h post-exercise, and energy intake was assessed 1h post-exercise through an ad libitum meal. Results: HIIE and MICE showed a trend to decrease ghrelin levels immediately post-exercise (-14.1 ± 21.6% and −9.6 ± 23.8%, respectively, p = 0.07) and decreased 1h post-exercise (-12.7 ± 31.8% and −13.8 ± 21.7%, respectively, p < 0.05). No changes were observed for post-exercise energy intake (p > 0.05). There was a positive correlation between the change in ghrelin levels and post-exercise energy intake only for HIIE (r = 0.63, p = 0.05). Conclusion: In summary, a single session of HIIE and MICE elicits a reduction on ghrelin levels without changing post-exercise energy intake in obese men.

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PURPOSE: To investigate the association between housing characteristics with objectively measured changes in physical activity (PA) and sedentary behavior (SB) during the COVID-19 pandemic in older adults with hypertension. METHODS: Thirty-five older adults with hypertension were included in this exploratory study. Accelerometer-based PA and SB measures were assessed before and during a period of social distancing policy imposed due to the COVID-19 pandemic. Housing type, housing surface area and household size were tested as predictors of changes in PA and SB. A generalized linear mixed model was used for the analysis. RESULTS: Housing type was associated with changes in PA and SB. Individuals residing in an apartment showed a greater decrease in light PA on weekdays (ß= -65 min/day, p=0.035) and a trend for an increase in SB (ß= 55 min/day, p=0.056) compared to those residing in a detached house. Individuals residing in a row house showed a greater decrease in moderate-vigorous PA (ß= -10 min/day, p=0.037) and steps/day (ß= -2064, p=0.010) compared to those residing in a detached house. Individuals residing in an apartment showed a greater decrease in light PA on the weekends (ß= -83 min/day, p=0.015) and an increase in SB (ß= 72 min/day, p=0.036) compared to those residing in a detached house. No association was found for housing surface area and household size. CONCLUSIONS: Older adults with hypertension residing in an apartment or row house have greater unhealthy changes in movement behavior during the COVID-19 pandemic. Further studies are needed to confirm our preliminary findings.

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This study investigated the acute post-exercise effect of high-velocity resistance exercise on ambulatory blood pressure in hypertensive older women. Fourteen volunteers (67.9±5.1 years) performed a high-velocity resistance exercise session (8 exercises using Thera-Band, 3 sets of 6 repetitions as fast as possible in the concentric phase with moderate intensity) and a control session, separated by a 7-10-day period. Ambulatory blood pressure was monitored following 12-h post-sessions and compared between conditions at 1 to 4-h, 5 to 8-h, and 9 to 12-h. Average 24-h ambulatory blood pressure, awake, asleep periods, and blood pressure load were also analyzed. There was a condition by time interaction for systolic ambulatory blood pressure over 12-h post-sessions (P=0.043). It was observed a lower systolic ambulatory blood pressure in the first 4-h period following the high-velocity resistance exercise session compared to the control session (-6.7 mmHg, 95% CI - 11.6 to -1.8 mmHg; P=0.011). No changes were observed for diastolic ambulatory blood pressure over 12-h post-sessions as well as for the other variables analyzed (P>0.05). In summary, a single high-velocity resistance exercise session elicits a post-exercise antihypertensive effect and may be considered as a strategy to acutely improve blood pressure control in hypertensive older women.

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This study aimed to investigate the effects of a 12-week self-selected resistance training (SSRT) program on physical fitness and psychophysiological responses among physically inactive older women. We randomly allocated 32 inactive older women (M age = 66.0 years, SD = 3.0) into either an SSRT (n = 16) or control group (n = 16). Participants performed SSRT three times per week over 12 weeks. We assessed maximal isotonic and isokinetic muscle strength, functional capacity, flexibility, cardiorespiratory fitness, and body composition at baseline and after the intervention. Affective responses and perceived exertion were evaluated after each exercise set throughout the training program. The SSRT group significantly improved their maximal muscle strength in all exercises (Cohen's d ranging from 1.4-3.3; all p's < .001), peak torque (knee flexors: d = 1.7; knee extensors: d = 1.6; all p < .001), flexibility (knee flexors: d = 1.7; single hip flexors: d = 1.6; all p < .001; bilateral hip flexors: d = 1.1, p = .001), fat-free mass (d = .9, p = .008), and cardiorespiratory fitness (d = .9, p = .014), compared to the control group. All components of functional capacity improved compared to the control group (Cohen's d ranging from .8 to 5.5; all p's ≤ .001). Participants perceived the exercise training sessions as pleasant and of low to moderate effort. Thus, a 12-week SSRT program was effective at improving physical fitness and inducing feelings of pleasure among inactive older women.

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OBJECTIVE: This study investigated the acute effects of high-intensity interval (HIIE) and moderate-intensity continuous (MICE) exercise on ghrelin levels in obese men. METHODS: A total of 10 obese men (age 27.6 ± 1.8 years, body mass index 35.4 ± 4.5 kg/m2, body fat 39.9 ± 2.1%) performed two exercise sessions in a randomized order: HIIE (10 × 1 min intervals at 90% of the maximal heart rate [HRmax] interspersed by 1 min of active recovery) and MICE (20 min at 70% of the HRmax). Ghrelin levels were assessed pre-, post- and 1h post-exercise, and energy intake was assessed 1h post-exercise through an ad libitum meal. RESULTS: HIIE and MICE showed a trend to decrease ghrelin levels immediately post-exercise (-14.1 ± 21.6% and -9.6 ± 23.8%, respectively, p = 0.07) and decreased 1h post-exercise (-12.7 ± 31.8% and -13.8 ± 21.7%, respectively, p < 0.05). No changes were observed for post-exercise energy intake (p > 0.05). There was a positive correlation between the change in ghrelin levels and post-exercise energy intake only for HIIE (r = 0.63, p = 0.05). CONCLUSION: In summary, a single session of HIIE and MICE elicits a reduction on ghrelin levels without changing post-exercise energy intake in obese men.

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PURPOSE: To investigate the short-term effect of self-selected training intensity (SSTI) on ambulatory blood pressure (BP) in hypertensive older women. PARTICIPANTS AND METHODS: This is a randomized, single-blind, two-arm, parallel-group controlled trial that included 40 medicated hypertensive older women (64.4±3.6 years; resting systolic 118±19 and diastolic BP 68±9 mmHg). SSTI intervention was performed three times per week, 30-50 minutes per session (n=20). The control group participated in health education meetings once per week (n=20). Ambulatory BP (primary outcome) and six-minute walking test performance (secondary outcome) were assessed at baseline and following 8 weeks of intervention. Heart rate (HR), rating of perceived exertion (RPE, 6-20), and affective valence (ie, feeling scale, -5/+5) were recorded during all SSTI sessions. Intention-to-treat and per-protocol analyses were used for data analyses. RESULTS: Fifteen participants from the SSTI group and 17 from the control group completed the study. No differences in ambulatory BP (24-h, awake, and asleep) were observed between SSTI and control groups (intention-to-treat and per-protocol analyses; p>0.05). The SSTI group showed a greater six-minute walking test performance than the control group in the intention-to-treat and per-protocol analyses (p<0.05). The participants exercised at 52±10% of HR reserve reported an RPE of 11±1 and an affective valence of 3.4±1.1 over the 8-week period. CONCLUSION: SSTI is a feasible approach to induce a more active lifestyle and increase health-related fitness in hypertensive older women, although it does not improve BP control over a short-term period.

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BACKGROUND: Studies have shown that low cardiorespiratory fitness (CRF) and low muscle strength are independently associated with metabolic syndrome (MetS) in older adults. This study investigated the isolated and combined associations of low CRF and muscle strength with MetS in older adults. METHODS: This cross-sectional study included 184 older adults (71% women; aged 65.6 ±â€¯4.3 years) without a prior history of cardiovascular disease. CRF and muscle strength were assessed by the six-minute walking test and 30-s chair stand test, respectively. Results below the 25th percentile of the cohort were used to define low CRF and low muscle strength. MetS was defined according to NCEP-ATP III criteria. Poisson's regression with robust variance was used to determine the prevalence ratio (PR) for MetS. Reference group was composed by older adults with both CRF and muscle strength above 25th percentile. RESULTS: Prevalence of low CRF, low muscle strength, and combined low CRF and muscle strength was 22.8%, 17.9%, and 10.9%, respectively. The prevalence of MetS was 56.5% in the full cohort. Isolated low CRF (PR 1.05, 95% CI 0.73 to 1.52; p = 0.793) and muscle strength (PR 1.09, 95% CI 0.74 to 1.61; p = 0.651) were not associated with MetS in the adjusted analysis. Combined low CRF and muscle strength was associated with MetS (PR 1.45, 95% CI 1.09 to 1.93; p = 0.011). CONCLUSIONS: Older adults with combined, but not isolated, low CRF and muscle strength showed an increased risk for MetS.

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Self-selected exercise intensity (SSE) is a simple approach to encourage an active lifestyle. This study aimed to investigate whether a SSE session meet the recommended intensity for hypertension management (i.e. moderate-vigorous), and whether heart rate (HR), rating of perceived exertion (RPE) and affective responses are reproducible. Thirteen inactive hypertensive older women (age: 64.54 ± 4.16 years; blood pressure: 122.51/62.15 mmHg) performed two 30-minute SSE sessions outdoors. HR reserve (HRR), RPE and affective responses were assessed. Paired t-test, intraclass correlation coefficient (ICC) and typical error (TE) were used for the analyzes. Participants exercised at moderate-vigorous intensity (≥ 40% of HRR). No differences were found for HRR (56.46 ± 8.01% vs. 59.08 ± 10.57%), RPE (11.26 ± 1.14 vs. 10.98 ± 1.52) and affective response (3.47 ± 1.13 vs. 3.38 ± 1.23) (p > 0.05). RPE showed excellent reliability (ICC = 0.82; 95%CI: 0.42; 0.94; p = 0.003). There was a poor reliability for HRR (ICC = 0.40; 95%CI: -0.97; 0.82; p = 0.193) and affective responses (ICC = 0.19; 95%CI: -2.10; 0.76; p = 0.369). TE between sessions for HRR, RPE, and affective response were 8.11 bpm, 0.75 and 1.11, respectively. In conclusion, inactive hypertensive older women seem to meet the recommended intensity for hypertension management when they exercise at a self-selected pace and report it as light-moderate and pleasant. Despite only RPE, but not HR and affective response, has shown good reproducibility, the results seem to support the use of SSE as a simple approach to encourage an active lifestyle in this population

O exercício em intensidade autosselecionada (EIA) é uma abordagem simples para encorajar um estilo de vida ativo. Este estudo investigou se o EIA atende a intensidade recomendada para tratamento de hiperten-são (i.e. moderada-vigorosa), e se a frequência cardíaca (FC), percepção de esforço (PSE) e resposta afetiva são reprodutíveis. Treze mulheres idosas hipertensas inativas (idade: 64,54 ± 4,16 anos; pressão arterial: 122,51/62,15 mmHg) realizaram duas sessões de EIA de 30 minutos ao ar livre. FC de reserva (FCR), PSE e resposta afetiva foram avaliadas. Teste t pareado, coeficiente de correção intraclasse (CCI) e erro tí-pico (ET) foram analisados. As participantes se exercitaram em intensidade moderada-vigorosa (≥ 40% da FCR). Não houve diferença na FCR (56,46 ± 8,01% vs. 59,08 ± 10,57%), PSE (11,26 ± 1,14 vs. 10,98 ± 1,52) e resposta afetiva (3,47 ± 1,13 vs. 3,38 ± 1,23; p > 0,05). A PSE apresentou excelente confiabilidade (CCI = 0,82; IC95%: 0,42; 0,94; p = 0,003). Houve baixa confiabilidade da FCR (CCI = 0,40; IC95%: -0,97; 0,82; p = 0,193) e resposta afetiva (CCI = 0,19; IC95%: -2,10; 0,76; p = 0,369). O ET foi de 8,11 bpm, 0,75 e 1,11 para FCR, PSE e resposta afetiva, respectivamente. Em conclusão, mulheres idosas hipertensas inativas parecem atender a intensidade recomendada para tratamento da hipertensão quando realizam EIA e relatam a atividade como leve-moderada e prazerosa. Embora apenas a PSE, e não a FCR e resposta afetiva, tenha mostrado boa reprodutibilidade, os resultados parecem suportar o EIA como uma abordagem simples para encorajar um estilo de vida ativo nessa população

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PURPOSE: Acute reduction in blood pressure (BP) following an exercise session is evidenced in controlled settings with formal supervision in hypertensive older populations. This study investigated the effect of a self-selected exercise (SSE)-intensity session on ambulatory BP in hypertensive older women in a "real-world" setting. METHODS: Twenty inactive older women with hypertension (64.9±4.5 years) were included in this randomized, controlled, crossover trial. After baseline assessments, participants performed 30 minutes of an SSE-intensity session on an outdoor track and a control session, separated by 7-10 days. Heart rate (HR), rating of perceived exertion (RPE), and affective response were assessed. Ambulatory BP was monitored for 20 hours following both sessions. Paired t-tests and generalized estimation were used for data analysis. RESULTS: Participants exercised at 5.1±1.1 km/h, spent ~90% of the exercise time at moderate-vigorous intensity (≥40% of heart rate reserve). SSE-intensity session was reported as light (RPE 11.0±1.5) and pleasant (affect 3.4±1.2). SSE-intensity session elicited reductions in systolic BP in the first 6 hours postexercise (6.0 mmHg, CI 2.7-9.3 mmHg; P<0.001). Average systolic BP in the 20-hour (-3.4 mmHg, CI -5.9 to -0.9 mmHg; P=0.010) and awake (-4.0 mmHg, CI -6.4 to -1.6 mmHg; P=0.003) periods were lower following SSE-intensity session compared to control session. No differences were observed in average systolic BP during asleep period and diastolic BP during the 20-hour awake and asleep periods between the SSE-intensity session and control session (P>0.05). CONCLUSION: An SSE-intensity session elicited a reduction in ambulatory systolic BP in inactive older women with hypertension during awake and 20-hour periods. Also, the SSE-intensity session was reported as light and pleasant.

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BACKGROUND: This study analyzed the effect of walking breaks or low-volume high-intensity interval exercise (LV-HIIE) on markers of metabolic syndrome relative to a day of prolonged sitting. METHODS: Twenty-five adults with excess body fat participated in this crossover trial: (1) 10-hour sitting day (SIT), (2) LV-HIIE followed by a sitting day (EX+SIT), and (3) sitting day with 5-minute walking breaks for every 20 minutes (SIT+WB). Glucose and blood pressure (BP) were measured before and 1 hour after 4 meals and 2 hours after lunch. Triglycerides were measured at baseline, 2, and 3.5 hours after lunch. Generalized mixed models were used to identify differences in the area under the curve (AUC) of BP and incremental AUC (iAUC) of glucose and triglycerides among the sessions. RESULTS: iAUC-glucose was lower in SIT+WB than SIT (ß = -35.3 mg/dL·10 h; 95% confidence interval, -52.5 to -8.2). AUC-diastolic BP was lower in SIT+WB than SIT (ß = -14.1 mm Hg·10 h; 95% confidence interval, -26.5 to -1.6) and EX+SIT (ß = -14.5 mm Hg·10 h; 95% confidence interval, -26.9 to -2.1). There were no differences in triglycerides and systolic BP levels among the sessions. CONCLUSION: Adults with excess body fat present lower glucose and diastolic BP during a day with breaks in sitting time compared with a prolonged sitting day with or without an LV-HIIE session.

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We compared physiological and psychological responses between low-volume high-intensity interval training (LV-HIIT) sessions with different work-recovery durations. Ten adult males performed two LV-HIIT sessions in a randomized, counter-balanced order. Specifically, 60/60 s LV-HIIT and 30/30 s LV-HIIT. Oxygen uptake (VO2), carbon dioxide output (VCO2), ventilation (VE), respiratory exchange ratio (RER), perceived exertion (RPE), and affect were assessed. During intervals, the VO2 (3.25 ± 0.57 vs. 2.83 ± 0.50 L/min), VCO2 (3.15 ± 0.61 vs. 2.93 ± 0.58 L/min), VE (108.59 ± 27.39 vs. 94.28 ± 24.98 L/min), and RPE (15.9 ± 1.5 vs. 13.9 ± 1.5) were higher (ps ≤ 0.01), while RER (0.98 ± 0.05 vs. 1.03 ± 0.03) and affect (-0.8 ± 1.4 vs. 1.1 ± 2.0) were lower (ps ≤ 0.007) in the 60/60 s LV-HIIT. During recovery periods, VO2 (1.85 ± 0.27 vs. 2.38 ± 0.46 L/min), VCO2 (2.15 ± 0.35 vs. 2.44 ± 0.45 L/min), and affect (0.6 ± 1.7 vs. 1.7 ± 1.8) were lower (ps ≤ 0.02), while RER (1.20 ± 0.05 vs. 1.03 ± 0.05; p < 0.001) was higher in the 60/60 s LV-HIIT. Shorter LV-HIIT (30 s) elicits lower physiological response and attenuated negative affect than longer LV-HIIT (60 s).

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We compared in-task affect to HIIE and MICE, and its relationship with time spent at different metabolic domains, perceived exertion (RPE), self-efficacy, enjoyment, and future intention of exercise in overweight inactive men. Muscle damage and soreness, and inflammation were assessed post-exercise. Fifteen participants (28.9 ±â€¯5.0 yr; 29.2 ±â€¯3.8 kg/m2) completed a HIIE (10 × 1 min at 100% Vmax, 1 min recovery) and MICE (20 min at 55-59% VO2reserve) session. Affect, alertness, RPE, and self-efficacy were assessed in-task, and enjoyment and future intention post-task. At baseline, 24 and 48 h, creatine kinase, lactate dehydrogenase, interleukin-6 and -10, tumor necrosis factor alpha, and muscle soreness were assessed. Affect (-3.1 ±â€¯1.8 vs. 0.8 ±â€¯1.8, P < .001) and self-efficacy (70 ±â€¯15 vs. 90 ±â€¯15%, P < .001) were lower, while RPE and alertness were higher in HIIE compared to MICE (Ps ≤ .02). Affect was negatively correlated with RPE in HIIE (r = -0.90) and MICE (r = -0.72), and time spent above respiratory compensation point in HIIE (r = -0.59). Affect was positively correlated with self-efficacy in MICE (r = 0.74). Enjoyment, future intention, muscle damage and soreness, and inflammation were similar between HIIE and MICE post-exercise. Therefore, in-task HIIE was experienced as unpleasant compared to MICE, but the psychological and physiological responses post-task were similar in overweight inactive men.

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O objetivo deste estudo foi analisar o efeito do tempo sentado prolongado sobre marcadores cardio-metabólicos em adultos fisicamente ativos e inativos. Participaram do estudo 10 adultos fisicamente ativos (27,30 ± 4,90 anos de idade) e 11 fisicamente inativos (26,27 ± 3,17 anos de idade). Todos realizaram uma sessão de tempo sentado prolongado de 10 horas, com quatro refeições padroniza-das. Os níveis de glicose e pressão arterial foram mensurados no jejum, antes e 1 hora após cada refeição e também 2 horas após o almoço. Os níveis de triglicerídeos foram medidos no jejum, 2 e 3,5 horas após o almoço. O modelo linear generalizado foi utilizado para comparar a área sob a curva incremental (ASCi) dos níveis de glicose e triglicerídeos e a área sob a curva (ASC) dos níveis de pressão arterial entre os grupos, com ajuste pelos valores de linha de base. O grupo fisicamente ativo apresentou menor ASCi para os níveis de glicose no período de 10 horas (ß = -5,55 mg/dL/10h; IC95%: -9,75; -1,33; p = 0,010) e no período da manhã (ß = -7,05 mg/dL/5h; IC95%: -12,11; -1,99; p = 0,006) comparado ao grupo fisicamente inativo. Não houve diferença da ASCi dos triglicerídeos (p = 0,517) e na ASC da pressão arterial (p = 0,145) entre os grupos. Em conclusão, adultos fisicamente ativos apresentaram melhor controle glicêmico comparados àqueles fisicamente inativos durante a exposição a tempo sentado prolongado

The purpose of this study was to analyze the effect of prolonged sitting time on cardiometabolic markers in physically active and inactive adults.Ten physically active adults (27.30 ± 4.90 years old) and 11 physically inactive (26.27 ± 3.17 years old) participated in the study. All performed a 10-hour long sitting session, with a total of four standardized meals. Glucose and blood pressure levels were measured at fasting, before and 1 hour after each meal, and 2 hours after lunch. Triglycerides levels were measured on fasting at 2 and 3.5 hours after lunch. The generalized linear model was used to compare the area under the incremental curve (AUCi) of the glucose and triglycerides lev-els, and the area under the curve (AUC) of the blood pressure levels between the groups, adjusted for baseline values. The physically active group showed lower blood glucose AUCi of 10 hours (ß = -5.55 mg/dL/10h; 95%CI: -9.75; -1.33, p = 0.010), and morning (ß = -7.05 mg/dL/5h; 95%CI: -12.11; -1.99, p = 0.006) compared to the physically inactive group. There was no difference in triglycerides AUCi (p = 0.517) and blood pressure AUC (p = 0.145) between groups. In conclusion, physically active adults have better glycemic control than physically inactive adults during exposure to prolonged sitting time

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