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Arch Pathol Lab Med ; 116(3): 274-6, 1992 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-1371381

RESUMEN

We report two cases of Paneth cell-like metaplasia of the prostate gland, one in poorly differentiated carcinoma and the second in benign hyperplasia. By light microscopy, the Paneth-like cells were indistinguishable from Paneth cells found in the normal small intestine and ultrastructurally showed electron-dense granules typical of Paneth cells. Immunohistochemical stains were positive for prostate-specific antigen and prostatic acid phosphatase and negative for lysozyme and alpha 1-antitrypsin. The clinical significance of Paneth cell-like metaplasia is unknown and may represent an example of the multipotential metaplastic capability of actively dividing cells.


Asunto(s)
Metaplasia/patología , Próstata/patología , Adenocarcinoma/patología , Anciano , Humanos , Masculino , Persona de Mediana Edad , Hiperplasia Prostática/patología , Neoplasias de la Próstata/patología
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