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J Am Acad Dermatol ; 72(6): 1027-35, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25824275

RESUMEN

BACKGROUND: Melanomas on chronically sun-damaged skin (CSDS) can be difficult to identify and often manifest morphologic features that overlap with benign lesions. OBJECTIVE: We describe and analyze the clinical and dermoscopic characteristics of melanomas on nonfacial CSDS. METHODS: Melanoma cases on nonfacial CSDS were retrospectively identified from the biopsy specimen logs of 6 melanoma clinics. Clinical and dermoscopic images were combined into 1 database. Demographics, clinical, dermoscopic, and histopathologic information were analyzed. Descriptive frequencies were calculated. RESULTS: One hundred eighty-six cases met the inclusion criteria: 142 melanomas in situ (76%) and 39 invasive (21%; mean thickness, 0.49 mm). Lentigo maligna was the most common histopathologic subtype (n = 76; 40.9%). The most frequent dermoscopic structures were granularity (n = 126; 67.7%) and angulated lines (n = 82; 44%). Vascular structures were more frequent in invasive melanomas (56% vs 12% of in situ melanomas). Most manifested 1 of 3 dermoscopic patterns: patchy peripheral pigmented islands, angulated lines, and tan structureless with granularity pattern. LIMITATIONS: This was a retrospective study, and evaluators were not blinded to the diagnosis. In addition, interobserver concordance and sensitivity and specificity for dermoscopic structures were not evaluated. CONCLUSION: Outlier lesions manifesting dermoscopic structures, such as granularity, angulated lines, or vessels and any of the 3 described dermoscopic patterns should raise suspicion for melanoma.


Asunto(s)
Dermoscopía/métodos , Peca Melanótica de Hutchinson/patología , Melanoma/patología , Neoplasias Cutáneas/patología , Luz Solar/efectos adversos , Adulto , Distribución por Edad , Anciano , Australia/epidemiología , Estudios de Cohortes , Detección Precoz del Cáncer/métodos , Femenino , Humanos , Peca Melanótica de Hutchinson/epidemiología , Peca Melanótica de Hutchinson/etiología , Incidencia , Masculino , Melanoma/epidemiología , Melanoma/etiología , Persona de Mediana Edad , Invasividad Neoplásica/patología , Estadificación de Neoplasias , Pronóstico , Estudios Retrospectivos , Medición de Riesgo , Distribución por Sexo , Neoplasias Cutáneas/epidemiología , Neoplasias Cutáneas/etiología , Rayos Ultravioleta/efectos adversos
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