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1.
Respir Care ; 2024 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-39013568

RESUMEN

BACKGROUND: PEEP is a cornerstone treatment for children with pediatric ARDS. Unfortunately, its titration is often performed solely by evaluating oxygen saturation, which can lead to inadequate PEEP level settings and consequent adverse effects. This study aimed to assess the impact of increasing PEEP on hemodynamics, respiratory system mechanics, and oxygenation in children with ARDS. METHODS: Children receiving mechanical ventilation and on pressure-controlled volume-guaranteed mode were prospectively assessed for inclusion. PEEP was sequentially changed to 5, 12, 10, 8 cm H2O, and again to 5 cm H2O. After 10 min at each PEEP level, hemodynamic, ventilatory, and oxygenation variables were collected. RESULTS: A total of 31 subjects were included, with median age and weight of 6 months and 6.3 kg, respectively. The main reasons for pediatric ICU admission were respiratory failure caused by acute viral bronchiolitis (45%) and community-acquired pneumonia (32%). Most subjects had mild or moderate ARDS (45% and 42%, respectively), with a median (interquartile range) oxygenation index of 8.4 (5.8-12.7). Oxygen saturation improved significantly when PEEP was increased. However, although no significant changes in blood pressure were observed, the median cardiac index at PEEP of 12 cm H2O was significantly lower than that observed at any other PEEP level (P = .001). Fourteen participants (45%) experienced a reduction in cardiac index of > 10% when PEEP was increased to 12 cm H2O. Also, the estimated oxygen delivery was significantly lower, at 12 cm H2O PEEP. Finally, respiratory system compliance significantly reduced when PEEP was increased. At a PEEP of 12 cm H2O, static compliance had a median reduction of 25% in relation to the initial assessment (PEEP of 5 cm H2O). CONCLUSIONS: Although it may improve arterial oxygen saturation, inappropriately high PEEP levels may reduce cardiac output, oxygen delivery, and respiratory system compliance in pediatric subjects with ARDS with low potential for lung recruitability.

2.
Pediatr Nephrol ; 39(7): 2235-2243, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38416215

RESUMEN

BACKGROUND: Acute kidney injury (AKI) is a common condition in critically ill children and is associated with increased morbidity and mortality. This study aimed to assess the performance of point-of-care ultrasonography to predict AKI in children undergoing cardiac surgery. METHODS: In this prospective study, consecutive children underwent kidney Doppler ultrasound examination within 24 h following cardiac surgery, and an experienced operator obtained both renal resistive index (RRI) and renal pulsatility index (RPI). AKI was defined by the Kidney Disease Improving Global Outcome (KDIGO) criteria. The primary outcome was the diagnosis of severe AKI (KDIGO stage 2 or 3) on day 3. RESULTS: A total of 58 patients were included. Median age and weight were 12.9 months (IQR 6.0-37.9) and 7.36 kg (IQR 5.19-11.40), respectively. On day 3, 13 patients were classified as having AKI, of which 11 were severe. RRI could effectively predict AKI (area under the ROC curve [AUC] 0.83, 95% CI 0.71-0.92; p < 0.001) as well as RPI (AUC 0.81, 95% CI 0.69-0.90; p < 0.001). The optimal cutoff value for RRI was 0.85 (sensitivity, 73%; specificity, 83%; positive predictive value [PPV], 50%; and negative predictive value [NPV], 93%), while for RPI was 1.95 (sensitivity, 73%; specificity, 78%; PPV, 44%; and NPV, 92%). Similar results were found in the analysis for prediction on day 5. Significant correlations were found between Doppler-based variables and estimated GFR and furosemide dose on day 3. CONCLUSIONS: Kidney Doppler ultrasound may be a promising tool for predicting AKI in children undergoing cardiac surgery.


Asunto(s)
Lesión Renal Aguda , Procedimientos Quirúrgicos Cardíacos , Valor Predictivo de las Pruebas , Ultrasonografía Doppler , Humanos , Lesión Renal Aguda/etiología , Lesión Renal Aguda/diagnóstico , Lesión Renal Aguda/diagnóstico por imagen , Masculino , Femenino , Lactante , Estudios Prospectivos , Ultrasonografía Doppler/métodos , Procedimientos Quirúrgicos Cardíacos/efectos adversos , Preescolar , Riñón/diagnóstico por imagen , Riñón/irrigación sanguínea , Riñón/fisiopatología , Arteria Renal/diagnóstico por imagen , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/diagnóstico por imagen , Flujo Pulsátil
3.
Pediatr Cardiol ; 2023 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-36759350

RESUMEN

Proper assessment of fluid responsiveness using accurate predictors is crucial to guide fluid therapy and avoid the serious adverse effects of fluid overload. The main objective of this study was to investigate the accuracy of respiratory variations in inferior vena cava diameter (∆IVC) to predict fluid responsiveness in mechanically ventilated children. This prospective single-center study included 32 children (median age and weight of 17 months and 10 kg, respectively) who received a fluid infusion of 10 ml kg-1 of crystalloid solutions over 10 min. ∆IVC and respiratory variation in aortic blood flow peak velocity (∆Vpeak) were determined over one controlled respiratory cycle before and after fluid loading. Thirteen (41%) participants were fluid-responders. ∆IVC, ∆Vpeak, stroke volume index, and cardiac index were found to be predictors of fluid responsiveness. However, the area under the ROC curve of ∆IVC was smaller when compared to ∆Vpeak (0.709 vs. 0.935, p < 0.012). The best cut-off values were 7.7% for ∆IVC (sensitivity, 69.2%; specificity 78.9%, positive predictive value, 69.2%; and negative predictive value, 78.9%) and 18.2% for ∆Vpeak (sensitivity, 84.6%; specificity, 89.5%; positive predictive value, 84.6%; negative predictive value, 89.5%). Changes in stroke volume were positively correlated with ∆IVC (ρ = 0.566, p < 0.001) and ∆Vpeak (ρ = 0.603, p < 0.001). A significant correlation was also found between changes in MAP and ∆Vpeak (ρ = 0.382; p = 0.031), but the same was not observed with ∆IVC (ρ = 0.011; p = 0.951). In conclusion, ∆IVC was found to have a moderate accuracy in predicting fluid responsiveness in mechanically ventilated children and is an inferior predictor when compared to ∆Vpeak.

4.
Pediatr Cardiol ; 43(2): 382-390, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-34518914

RESUMEN

An accurate assessment of cardiovascular performance is essential to predict and evaluate hemodynamic response to interventions. The objective of this prospective study was to assess whether point-of-care ultrasonography of the common carotid artery (CCA) can estimate the stroke volume (SV) and cardiac index (Ci) of critically ill children. Participants underwent Doppler ultrasonography of the left CCA and transthoracic echocardiography (TTE). Variables measured by TTE were SV and Ci. Carotid blood flow (CBF) was calculated based on both systolic velocity-time integral (CBF(s)) and total velocity-time integral (CBF(t)). Carotid corrected flow time(CFT)was also determined. A total of 50 children were enrolled. The median age and weight of participants were 36.0 months and 14.2 kg, respectively. Both CBF(s) and CBF(t) correlated very strongly with SV (ρ = 0.98 and 0.97, respectively) and Ci (ρ = 0.96 and 0.92, respectively). Agreement analysis showed low biases and clinically acceptable percentage errors between variables measured by TTE (SV and Ci) and those estimated by Doppler ultrasonography. Linear regression analysis revealed that the Ci of mechanically ventilated children can be estimated by the following equation: [Formula: see text]. CFT did not significantly correlate with SV or Ci (ρ = 0.27 and 0.05, respectively). Doppler ultrasonography of the left CCA is able to estimate the SV and Ci of critically ill children. Therefore, the CDU may be considered as an alternative for estimating Ci in critically ill children when TTE is not feasible or available.


Asunto(s)
Enfermedad Crítica , Hemodinámica , Niño , Humanos , Estudios Prospectivos , Volumen Sistólico/fisiología , Ultrasonografía , Ultrasonografía Doppler
5.
J. pediatr. (Rio J.) ; 97(5): 564-570, Sept.-Oct. 2021. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1340152

RESUMEN

Abstract Objective: To evaluate the influence of intra-abdominal pressure on the cardiac index (CI) at different intra-abdominal hypertension grades achieved when performing an abdominal compression maneuver (ACM). Evaluating the effectiveness of the ACM in distending the left internal jugular vein (LIJV). Methods: Prospective observational study conducted in the PICU of a quaternary care teaching hospital. Participants underwent the ACM and the IAP was measured with an indwelling urinary catheter. At each IAH grade reached during the ACM, the CI was measured by transthoracic echocardiography and the LIJV cross-sectional area (CSA) was determined by ultrasonography. Results: Twenty-four children were included (median age and weight of 3.5 months and 6.37 kg, respectively). The median CI observed at baseline and during IAH grades I, II, III, and IV were 3.65 L/min/m2 (IQR 3.12−4.03), 3.38 L/min/m2 (IQR 3.04−3.73), 3.16 L/min/m2 (IQR 2.70−3.53), 2.89 L/min/m2 (IQR 2.38−3.22), and 2.42 L/min/m2 (IQR 1.91−2.79), respectively. A 25% increase in the LIJV CSA area was achieved in 14 participants (58%) during the ACM. Conclusion: The ACM significantly increases IAP, causing severe reversible impairment in the cardiovascular system and is effective in distending the LIJV in just over half of the subjects. Even low levels of HIA can result in significant cardiac dysfunction in children. Therefore, health professionals should be aware of the negative hemodynamic repercussions caused by the increased IAP.


Asunto(s)
Humanos , Niño , Enfermedad Crítica , Hipertensión Intraabdominal , Estudios Prospectivos , Ultrasonografía , Hemodinámica
6.
Clin Nutr ; 40(8): 4871-4877, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-34358831

RESUMEN

BACKGROUND & AIMS: Due to the lack of validated methods of muscle assessment, sarcopenia is not well described in critically ill children. The main objectives of this study were to assess muscle wasting using point-of-care ultrasound (POCUS) and anthropometry, as well as its association with nutrition delivery in PICU. METHODS: This was a single-center, prospective cohort study, including consecutive children admitted to the PICU. Quadriceps femoris muscle thickness (QFMT) and anthropometrics measurements were performed at admission and then weekly until the 14th day of the PICU stay. The three moments of assessment were defined as T0 (baseline), T1 (7th day) and T2 (14th day). For analysis purposes, participants assessed only in T0 and T1 were defined as Subgroup 1, while those assessed in T0, T1 and T2 were defined as Subgroup 2. Actual total daily intake was determined by patient intake records until discharge or during the first 14 full days of PICU admission. RESULTS: In all, 119 patients were included with a median age of 12.0 months (IQR 4.0-42.5). In Subgroup 1, QFMT significantly decreased between T0 and T1 (-12.93 ± 14.07 %; p < 0.001), and the same was observed in Subgroup 2 (-13.81 ± 13.05 %; p < 0.001). However, no differences in QFMT was observed between T1 and T2 (-2.06 ± 13.80 %; p = 0.936). Triceps skinfold thickness, mid-upper arm circumference, and upper arm muscle area presented a similar pattern of changes between periods in both groups. Decrease of QFMT at T1 was significantly correlated with the cumulative protein deficit in both subgroups, but not with the cumulative energy deficit. CONCLUSION: Substantial muscle wasting occurs early in critically ill children and may be related to insufficient protein delivery. Anthropometric measurements are valuable in PICU and POCUS has the potential to play a major role in sarcopenia assessment during critical illnesses. TRIAL REGISTRATION: Brazilian Clinical Trials registry, registration number: RBR-85YYGN.


Asunto(s)
Antropometría/métodos , Pruebas en el Punto de Atención , Sarcopenia/diagnóstico , Ultrasonografía/métodos , Preescolar , Enfermedad Crítica , Femenino , Humanos , Lactante , Unidades de Cuidado Intensivo Pediátrico , Masculino , Atrofia Muscular/diagnóstico , Atrofia Muscular/etiología , Estudios Prospectivos , Músculo Cuádriceps/diagnóstico por imagen , Sarcopenia/etiología , Grosor de los Pliegues Cutáneos
7.
Pediatr Pulmonol ; 56(7): 1872-1888, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-33902159

RESUMEN

BACKGROUND: High-frequency oscillatory ventilation (HFOV) is an alternative mechanical ventilation mode proposed to reduce ventilator-induced lung injuries and improve clinical outcomes. The aim of this study was to determine the effects of HFOV compared to conventional mechanical ventilation (CMV) when used in children with hypoxemic respiratory failure. METHODS: The literature search was conducted to identify all studies published before December 2020. Eligible studies included a population aged between 28 days and 18 years old, presented original data from randomized controlled trials (RCTs) or observational studies, compared the use of HFOV with CMV. Meta-analyses of the pooled data were performed by using random-effects models with inverse-variance weighting. RESULTS: A total of 11 studies (2605 cases) were included, most of them evaluating patients with acute respiratory distress syndrome. The mean age of participants was 8.2 months and the mean oxygenation index of those included in the RCTs was 24.4. The effect of HFOV on mortality was not significant, and clinically significant harm or benefit could not be excluded (risk ratio [RR], 0.93; 95% confidence interval [CI], 0.72 to 1.20). No significant difference between groups was found in duration of mechanical ventilation (-2.23; 95% CI, -5.07 to 0.61), treatment failure (RR, 0.28; 95% CI, 0.08 to 1.02), and occurrence of barotrauma (RR, 0.88; 95% CI, 0.39 to 1.99). CONCLUSION: The scarce evidence currently available does not allow us to conclude that HFOV has advantages over CMV and further studies are needed to clarify its role in the treatment of acute hypoxemic respiratory failure in children.


Asunto(s)
Ventilación de Alta Frecuencia , Síndrome de Dificultad Respiratoria , Insuficiencia Respiratoria , Adulto , Niño , Preescolar , Humanos , Ventilación con Presión Positiva Intermitente , Respiración Artificial , Síndrome de Dificultad Respiratoria/terapia , Insuficiencia Respiratoria/terapia
8.
J Pediatr (Rio J) ; 97(5): 564-570, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33358965

RESUMEN

OBJECTIVE: To evaluate the influence of intra-abdominal pressure on the cardiac index (CI) at different intra-abdominal hypertension grades achieved when performing an abdominal compression maneuver (ACM). Evaluating the effectiveness of the ACM in distending the left internal jugular vein (LIJV). METHODS: Prospective observational study conducted in the PICU of a quaternary care teaching hospital. Participants underwent the ACM and the IAP was measured with an indwelling urinary catheter. At each IAH grade reached during the ACM, the CI was measured by transthoracic echocardiography and the LIJV cross-sectional area (CSA) was determined by ultrasonography. RESULTS: Twenty-four children were included (median age and weight of 3.5 months and 6.37kg, respectively). The median CI observed at baseline and during IAH grades I, II, III, and IV were 3.65L/min/m2 (IQR 3.12-4.03), 3.38L/min/m2 (IQR 3.04-3.73), 3.16L/min/m2 (IQR 2.70-3.53), 2.89L/min/m2 (IQR 2.38-3.22), and 2.42L/min/m2 (IQR 1.91-2.79), respectively. A 25% increase in the LIJV CSA area was achieved in 14 participants (58%) during the ACM. CONCLUSION: The ACM significantly increases IAP, causing severe reversible impairment in the cardiovascular system and is effective in distending the LIJV in just over half of the subjects. Even low levels of HIA can result in significant cardiac dysfunction in children. Therefore, health professionals should be aware of the negative hemodynamic repercussions caused by the increased IAP.


Asunto(s)
Enfermedad Crítica , Hipertensión Intraabdominal , Niño , Hemodinámica , Humanos , Estudios Prospectivos , Ultrasonografía
9.
Pediatr Pulmonol ; 55(8): 1892-1899, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32492251

RESUMEN

BACKGROUND: The coronavirus disease 2019 (COVID-19) outbreak is an unprecedented global public health challenge, leading to thousands of deaths every day worldwide. Despite the epidemiological importance, clinical patterns of children with COVID-19 remain unclear. The aim of this study was to describe the clinical, laboratorial, and radiological characteristics of children with COVID-19. METHODS: The Medline database was searched between December 1st 2019 and April 6th 2020. No language restrictions were applied. Inclusion criteria were (a) studied patients younger than 18 years old; (b) presented original data from cases of COVID-19 confirmed by reverse-transcription polymerase chain reaction; and (c) contained descriptions of clinical manifestations, laboratory tests, or radiological examinations. RESULTS: A total of 38 studies (1124 cases) were included. From all the cases, 1117 had their severity classified: 14.2% were asymptomatic, 36.3% were mild, 46.0% were moderate, 2.1% were severe, and 1.2% were critical. The most prevalent symptom was fever (47.5%), followed by cough (41.5%), nasal symptoms (11.2%), diarrhea (8.1%), and nausea/vomiting (7.1%). One hundred forty-five (36.9%) children were diagnosed with pneumonia and 43 (10.9%) upper airway infections were reported. Reduced lymphocyte count was reported in 12.9% of cases. Abnormalities in computed tomography were reported in 63.0% of cases. The most prevalent abnormalities reported were ground-glass opacities, patchy shadows, and consolidations. Only one death was reported. CONCLUSIONS: Clinical manifestations of children with COVID-19 differ widely from adult cases. Fever and respiratory symptoms should not be considered a hallmark of COVID-19 in children.


Asunto(s)
Infecciones por Coronavirus/diagnóstico , Tos/etiología , Fiebre/etiología , Neumonía Viral/diagnóstico , Adolescente , Betacoronavirus , COVID-19 , Prueba de COVID-19 , Niño , Preescolar , Técnicas de Laboratorio Clínico , Infecciones por Coronavirus/diagnóstico por imagen , Infecciones por Coronavirus/epidemiología , Eritema/etiología , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Pandemias , Neumonía Viral/diagnóstico por imagen , Neumonía Viral/epidemiología , Pronóstico , Infecciones del Sistema Respiratorio/etiología , SARS-CoV-2 , Taquicardia/etiología , Taquipnea/etiología , Tomografía Computarizada por Rayos X , Vómitos/etiología
10.
Pediatr Crit Care Med ; 21(4): e186-e191, 2020 04.
Artículo en Inglés | MEDLINE | ID: mdl-32084100

RESUMEN

OBJECTIVES: Inferior vena cava ultrasound has been used as a predictor of fluid responsiveness in children. Two ultrasonographic modes can be used to measure the respiratory variation of inferior vena cava diameter: M-mode and B-mode. Inconsistencies in measurements between the modes can result in inaccuracies in commonly used indices that assess fluid responsiveness. Our primary objective was to determine whether there are differences in the ultrasound-based measurements between these two modes of evaluation, which would impact respiratory variation of inferior vena cava diameter calculation. Our secondary objective was to assess inferior vena cava displacements during the respiratory cycle as a possible mechanism for measurement differences between the modes. DESIGN: Prospective observational study. SETTING: PICU of a tertiary care teaching hospital. PATIENTS: Seventy-three children under controlled ventilation (median age of 16 mo and weight of 10 kg). INTERVENTIONS: The inferior vena cava diameters were measured using a longitudinal view using B- and M-mode ultrasound. Two respiratory variation of inferior vena cava diameter indices were evaluated: distensibility and respiratory variation. Maximum craniocaudal and mediolateral displacements of the inferior vena cava were measured using the B-mode ultrasound. MEASUREMENTS AND MAIN RESULTS: Maximum diameters of the inferior vena cava were similar between the B- and M-modes (7.90 vs 7.90 mm, respectively; p = 0.326), but minimum diameters were smaller when measured by M-mode (6.36 vs 5.00 mm; p = 0.003). When calculated by data obtained from M-mode, respiratory variation of inferior vena cava diameter indices presented significantly higher values compared to B-mode measures (p ≤ 0.001, for both). Median inferior vena cava displacements were 5.00 mm (interquartile range, 3.68-6.26 mm) in the craniocaudal and 0.80 mm (interquartile range, 0.12-1.23 mm) in the mediolateral directions. CONCLUSIONS: There is a significant difference between measurements of the minimum inferior vena cava diameter observed in M- and B-mode ultrasound during the respiratory cycle in children under controlled ventilation. This results in imprecise respiratory variation of inferior vena cava diameter indices. Displacements of the inferior vena cava during the respiratory cycle may influence the reliability of ultrasonographic measurements, particularly in M-mode.


Asunto(s)
Ecocardiografía , Vena Cava Inferior , Niño , Humanos , Estudios Prospectivos , Reproducibilidad de los Resultados , Ultrasonografía , Vena Cava Inferior/diagnóstico por imagen
11.
Rev Assoc Med Bras (1992) ; 51(4): 237-40, 2005.
Artículo en Portugués | MEDLINE | ID: mdl-16127586

RESUMEN

BACKGROUND: Describe clinical and epidemiological characteristics of pediatric patients diagnosed with acute diarrhea and shock, admitted to the pediatric intensive care unit, in order to compare the evolution of clinical data between the survival and non-survival groups, thereby identifying the risk factors of death. METHODS: In the Pediatric Intensive Care Unit of the Clinical Hospital at the State University of Campinas (UNICAMP), a non-controlled, descriptive and retrospective study was carried out from February 1994 to January 1998 The epidemiological and clinical/evolution data were analyzed and the groups of those who survived (56) and did not survive (15) were compared. For continuous variables, the Chi-Square test was used and for categorical variables, the Fisher's Exact test, for values lower than five. RESULTS: Seventy one children aged from 0.4 to 13.9 months were admitted, 15 of them died (21.2%). Low birth weight was found in 18.1% and the mean breast-feeding time was 1.1 months. The average length of stay was 5.6 days. 52/71 children needed mechanical ventilation, use of vasoactive drugs and sodium bicarbonate was necessary in 23/71 and 15/71, respectively. 93% of children were given antibiotics. The use of sodium bicarbonate, vasoactive drugs and mechanical ventilation showed an association with risk of death, but only vasoactive drugs (OR=18.56) and an age less than 3 months (OR=0.10) showed a statistically significant difference in multivariate analysis. CONCLUSIONS: Acute diarrhea and shock occurred mainly in children under 3 months of age with a severe clinical/laboratorial condition. During clinical evolution, the high risk of death was related to the use of vasoactive drugs, a support therapy used in critical patients.


Asunto(s)
Diarrea/mortalidad , Unidades de Cuidado Intensivo Pediátrico , Choque/mortalidad , Enfermedad Aguda , Distribución por Edad , Brasil/epidemiología , Métodos Epidemiológicos , Femenino , Humanos , Lactante , Masculino , Distribución por Sexo
12.
Rev. Assoc. Med. Bras. (1992, Impr.) ; 51(4): 237-240, jul.-ago. 2005. tab
Artículo en Portugués | LILACS | ID: lil-411213

RESUMEN

OBJETIVOS: Descrever características clínicas e epidemiológicas de criancas com diarréia aguda e choque, admitidas em unidade de terapia intensiva pediátrica, e comparar a evolucão clínica entre os grupos óbito e sobrevida, identificando fatores associados ao óbito. MÉTODOS: Estudo descritivo, retrospectivo, não controlado, no período de fevereiro de 1994 a janeiro de 1998. Os dados epidemiológicos e clínico-evolutivos dos pacientes foram analisados e os grupos de pacientes com sobrevida e com óbito foram comparados. O teste Qui-quadrado foi utilizado para variáveis contínuas, e o teste exato de Fisher para as variáveis categóricas (valores menores que cinco). RESULTADOS: Foram admitidas 71 criancas, com idade entre 0,4 e 13,9 meses. Evoluíram para óbito 15. Baixo peso de nascimento foi encontrado em 18,1 por cento dos pacientes, tempo médio de aleitamento materno de 1,1 mês e de internacão de 5,6 dias. Receberam antibióticos 93 por cento das criancas. Necessitaram de ventilacão pulmonar mecânica 52/71 criancas, uso de drogas vasoativas 23/70 e uso de bicarbonato de sódio 15/71; estas variáveis estiveram associadas com maior risco de óbito, na análise univariada. No modelo multivariado, permaneceram como significantes o parâmetro droga vasoativa (OR=18,56) e idade menor que três meses (OR=0,10). CONCLUSÕES: A diarréia aguda e choque ocorreram principalmente em criancas com menos de três meses de idade, com apresentacão clínica e laboratorial de gravidade. Na evolucão clínica, a utilizacão de terapia de suporte em paciente crítico esteve associada ao óbito, com destaque para o uso de droga vasoativa.


Asunto(s)
Lactante , Humanos , Masculino , Femenino , Diarrea/mortalidad , Unidades de Cuidado Intensivo Pediátrico , Choque/mortalidad , Enfermedad Aguda , Distribución por Edad , Brasil/epidemiología , Métodos Epidemiológicos , Distribución por Sexo
13.
Arq. neuropsiquiatr ; 60(4): 967-970, Dec. 2002. graf
Artículo en Portugués | LILACS | ID: lil-326170

RESUMEN

OBJETIVO:Análise de 52 pacientes pediátricos com trauma de crânio (TCE) assistidos em Unidade de Terapia Intensiva, considerando fatores epidemiológicos do trauma, manifestações clínicas, aspectos tomográficos, variações hemodinâmicas e opções de tratamento da hipertensão intracraniana; avaliar a utilização da monitorização da pressão intracraniana (PIC). MÉTODO:Estudoretrospectivo de 52 pacientes com TCE e 17 destes submetidos a monitorização da PIC. RESULTADO:Houve predominância masculina e a média de idade foi 7,75 anos. Atropelamento foi a principal causa (38,5% dos casos). Encontramos 21,2% dos pacientes com hipotensão arterial. Foram classificados como TCE grave 67,3% dos pacientes. Tivemos graduação tomográfica de Marshall tipo I em 19,2%, II em 65,4%, III em 3,8%, IV em 3,8% e V em 7,7%. Apresentaram crise convulsiva 25%. Foram submetidos a monitorização da PIC 32,7%. A taxa de mortalidade foi 11,5%. O maior valor pressórico ocorreu no segundo dia em 58,8%. CONCLUSÃO: O prognóstico se relacionou com a severidade do trauma, hipotensão arterial, graduação tomográfica de Marshall tipo III e IV e altos valores de PIC. A monitorização da PIC permite facilidades no diagnóstico e tratamento da hipertensão intracraniana


Asunto(s)
Humanos , Masculino , Femenino , Lactante , Preescolar , Niño , Traumatismos Craneocerebrales , Unidades de Cuidado Intensivo Pediátrico , Presión Intracraneal , Traumatismos Craneocerebrales , Hipoxia , Hipertensión Intracraneal , Hipotensión Intracraneal , Monitoreo Fisiológico , Pronóstico , Estudios Retrospectivos , Índice de Severidad de la Enfermedad
14.
Arq Neuropsiquiatr ; 60(4): 967-70, 2002 Dec.
Artículo en Portugués | MEDLINE | ID: mdl-12563390

RESUMEN

OBJECTIVES: Analysis of 52 pediatric patients with head trauma assisted at Intensive Care Unit; to present considerations about epidemiologic factors of trauma, clinical presentation, tomografic aspects, hemodynamic changes and treatment options of intracranial hypertension; to present considerations about the intracranial pressure (ICP) monitoring. METHOD: Retrospective study involving 52 patients with head trauma and 17 patients submitted to a ICP monitoring. RESULTS: We found a male predominance, mean age 7.75 years-old, main cause was run over (38.5%); 21.2% patients presentd arterial hypotension; 67.3% were considered severe head trauma. According to Marshall tomografic grading we had 19.2% type I, 65.4% type II, 3.8% type III, 3.8% type IV and 7.7% type V. Seizures occurred in 25% children ICP monitoring was made in 32.7% of all patients. Mortality rate was 11.5%. In 58% the maximum ICP level occured at the second day of trauma. CONCLUSION: Prognosis was related to severity of trauma, arterial hypotension, Marshall's tomografic gradind III and IV and ICP high values. The ICP monitoring was considered useful to allow the identification and treatment of intracranial hypertension.


Asunto(s)
Traumatismos Craneocerebrales/fisiopatología , Unidades de Cuidado Intensivo Pediátrico , Presión Intracraneal , Niño , Preescolar , Traumatismos Craneocerebrales/terapia , Femenino , Humanos , Hipoxia/prevención & control , Lactante , Hipertensión Intracraneal/diagnóstico , Hipertensión Intracraneal/terapia , Hipotensión Intracraneal/prevención & control , Masculino , Monitoreo Fisiológico , Pronóstico , Estudios Retrospectivos , Índices de Gravedad del Trauma
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