RESUMEN

Aspergillosis and zygomycosis are life-threatening fungal infections in immunocompromised patients. We report a heart transplant recipient with an early pulmonary invasive aspergillosis successfully treated with association of voriconazole and caspofungin. Zygomycosis sinusitis, which was diagnosed while he still was on voriconazole therapy, was successfully treated with the use of combination antifungal therapy including liposomal amphotericin plus posaconazole and conservative surgical debridement.

Asunto(s)

Anfotericina B/uso terapéutico , Antifúngicos/uso terapéutico , Trasplante de Corazón/efectos adversos , Aspergilosis Pulmonar Invasiva/complicaciones , Sinusitis/tratamiento farmacológico , Triazoles/uso terapéutico , Cigomicosis/tratamiento farmacológico , Desbridamiento , Quimioterapia Combinada , Humanos , Huésped Inmunocomprometido , Aspergilosis Pulmonar Invasiva/tratamiento farmacológico , Aspergilosis Pulmonar Invasiva/microbiología , Masculino , Persona de Mediana Edad , Pirimidinas , Sinusitis/diagnóstico , Sinusitis/microbiología , Sinusitis/cirugía , Resultado del Tratamiento , Voriconazol , Cigomicosis/diagnóstico , Cigomicosis/microbiología , Cigomicosis/cirugía