RESUMEN

The antioxidant activity and protective effect in the toxicity model of H2O2 were studied for arachidonic (AA-CHOL), docosahexaenoic (DHA-CHOL), linoleic (Ln-CHOL), and oleic (Ol-CHOL) fatty acids, as well as arachidonoyl dicholine (AA-diCHOL) and O-arachidonoyl bistetramethylaminoisopropanol (ABTAP). AA-CHOL, DHA-CHOL and Ln-CHOL provided a 20% increase in cell survival. AA-CHOL, AA-diCHOL, Ol-CHOL, and ABTAP had a radical-scavenging effect in the ABTS test, approximately equal to the activity of a standard radical scavenger Trolox.

Asunto(s)

Antioxidantes/química , Ácidos Araquidónicos/química , Colina/química , 2-Propanol/química , Ácido Araquidónico/química , Línea Celular Tumoral , Cromanos/química , Ácidos Docosahexaenoicos/química , Ensayos de Selección de Medicamentos Antitumorales , Ácidos Grasos , Radicales Libres/química , Humanos , Peróxido de Hidrógeno/química , Ácido Linoleico/química , Ácido Oléico/química