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Acta Biotheor ; 69(3): 257-276, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-33502640

RESUMEN

A nonlinear differential equation model is proposed to study the dynamics of HIV/AIDS and its effects on workforce productivity. The disease-free equilibrium point of the model is shown to be locally asymptotically stable when the associated basic reproduction number [Formula: see text] is less than unity. The model is also shown to exhibit multiple endemic states for some parameter values when [Formula: see text] and [Formula: see text]. Global asymptotic stability of the disease-free equilibrium is guaranteed only when the fractions of the Susceptible subclass populations are within some bounds. Optimal control analysis of the model revealed that the most cost effective strategy that should be adopted in the fight against HIV/AIDS spread within the workforce is one that seeks to prevent infections and the treatment of infected individuals.


Asunto(s)
Infecciones por VIH , Dinámicas no Lineales , Número Básico de Reproducción , Simulación por Computador , Infecciones por VIH/epidemiología , Infecciones por VIH/prevención & control , Humanos , Modelos Biológicos
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