RESUMEN
The aim of this study is to assess and reduce the risk due to manual material handling in a company involved in the foodstuff retailing. The risk assessment was performed by NIOSH Variable Lifing Index in 13 different occupational conditions. As result the risk was present in any case, with VLI values ranging from 2.12 to 2.81. A good risk reduction has been accomplished correcting properly the most important multiplier involved in the computation of the revised NIOSH Lifting equation (lifting frequency and weight of heavier products). Even if the performed risk reduction has been significant, the residual risk is still higher than the level of acceptability.
Asunto(s)
Ergonomía , Industria de Alimentos , Elevación , Humanos , Medición de RiesgoRESUMEN
By using immunohistochemical techniques applied to confocal microscopy, the presence of aquaporin 3 water channel in the epidermis of Triturus italicus (Amphibia, Urodela) has been shown. We analysed the expression of aquaporin 3 (AQP3) during the larval, pre-metamorphic and adult phases; we also showed the localization of the water-channel protein AQP3 in free-swimming conditions and during aestivation in parallel with histological analysis of the skin, focusing on the possible relationship between protein expression and terrestrial habitats. Our results indicate that aquaporin is produced as the epidermis modifies during the functional maturation phase starting at the climax. Moreover, our data suggest an increase in enzyme expression in aestivating newts emphasizing the putative functional importance of differential expression related to a distinct phase of the biological cycle.
Asunto(s)
Acuaporina 3/biosíntesis , Regulación del Desarrollo de la Expresión Génica , Triturus/metabolismo , Animales , Estivación/fisiología , Inmunohistoquímica , Larva/metabolismo , Microscopía Confocal , Triturus/crecimiento & desarrolloRESUMEN
Recent reports suggest an association between Chlamydia pneumoniae and chronic coronary heart disease. This case-control study investigates the relationship between the presence of immunoglobin G (IgG) and immunoglobin A (IgA) when measured by means of microimmunofluorescence (MIF) and angiographically diagnosed coronary disease. Cases (n = 150) were angiography patients with at least one coronary artery lesion occupying at least 50% of the luminal diameter. Controls (n = 49) were angiography patients with no detectable signs of coronary artery disease and patients (n = 56) without signs or symptoms of coronary disease and with normal ECG results. No significant differences were revealed between the seroprevalence of IgG and IaA and geometric mean titers (GMT) as measured in cases and controls. When cases were compared with controls whose angiographic results were normal, after adjusting for established risk factors (cholesterol, smoking, hypertension, diabetes, age, gender and family history), the estimated risk of coronary artery disease was 0.79 (95% confidence interval (C.I.), 0.31-1.99) for the presence of IgG and was 0.94 (95 C.I., 0.37-2.39) for IgA. When cases were compared with controls with normal ECG results, the adjusted odds ratio (O.R.) for coronary artery disease was 1.17 (95%, C.I., 0.52-2.62) for the presence of IgG and 0.82 195% C.I., 0.36-1.86) for the presence of IgA. These results do not support an association between C. pneumoniae infection and coronary disease.
Asunto(s)
Anticuerpos Antibacterianos/análisis , Chlamydophila pneumoniae/aislamiento & purificación , Angiografía Coronaria , Enfermedad Coronaria/microbiología , Estudios de Casos y Controles , Enfermedad Crónica , Enfermedad Coronaria/diagnóstico por imagen , Femenino , Humanos , Inmunoglobulina A/sangre , Inmunoglobulina G/sangre , Italia/epidemiología , Masculino , Persona de Mediana Edad , Estudios SeroepidemiológicosRESUMEN
The purpose and design of behavioral objectives in educational programs are reviewed, and the behavioral objectives of a pharmacy residency program are listed. The behavioral objectives for the program follow, as a guide, the ASHP Accreditation Standard for Pharmacy Residency in a Hospital.