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INTRODUCTION: No clinical studies have examined the effect of mineral trioxide aggregate (MTA) obturation levels on the outcome of endodontic retreatment. This retrospective study examined treatment outcomes in three cohorts that compared overfilling, flush filling, and underfilling after orthograde retreatment using MTA. METHODS: Two hundred fifty patients with 264 teeth diagnosed with previously treated root canals and apical periodontitis retreated in a private endodontic practice were included. All teeth received MTA obturation and the extent of the final filling level was measured in relation to the major apical foramen. After 6-month follow-ups, all nonhealing cases were treated surgically. After 24- to 72-month reviews, the effect of preoperative lesion size and the degree of MTA obturation level were assessed. Multiple linear regression and time-to-event analysis using Stata 17 software (StataCorp LLC, College Station, TX) were used to evaluate the data. RESULTS: Within the three cohorts, 99 out of 108 overfilled teeth (91.7%), 90 out of 103 flush fills (87.4%), and 10 out of 53 underfilled teeth (18.9%) healed and were successfully retreated without surgery at 48-months. When surgical outcomes were included, the combined healed proportion was 93.2%. Preoperative lesion size was found to be an important predictor for retreatment nonhealing. A 1-mm increase in lesion size at baseline resulted in an estimated 11% (95% CI 1.04, 1.18)-38% (95% CI 1.22, 1.58) increase in the risk of surgery. Compared to overfilling and flush filling, underfilling was associated with an approximately three-fold increase in requiring surgery and characterized by delayed healing. CONCLUSION: MTA obturation is a viable retreatment option for teeth with nonhealing endodontic treatment. MTA overfills or flush fillings do not adversely affect healing outcomes. However, MTA underfilling increases the chances for nonhealing and surgical intervention.

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The penetration depth and extent of mineral trioxide aggregate (MTA) crystallisation into dentinal tubules at 2, 4 and 6 weeks after chelation and MTA obturation were investigated. Standardised 12 mm human root specimens (45) were prepared with NiTi rotary files using 4% NaOCl irrigation. They were randomly allocated to three irrigants (n = 15: 4% NaOCl, 15% ethylenediaminetetraacetic acid or Edgemix) and obturated with sodium fluorescein tagged ProRoot MTA. One millimetre thick apical, middle and coronal sections were examined using confocal laser scanning microscopy to determine MTA penetration depth and area. Depths varied from 352 to 1821 µm at 6 weeks depending on section level and were unaffected by chelation. No differences (p > 0.05) were found in mean maximum penetration depth or dentine area (%) between the 3 irrigants at all time intervals. MTA mineralisation penetrated up to 90% of dentinal tubules and can extend to the cementum in roots with patent, non-infected tubules.

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INTRODUCTION: No clinical studies have examined the effect of mineral trioxide aggregate (MTA) obturation levels on the outcome of endodontic retreatment. This retrospective study examined treatment outcomes in three cohorts that compared overfilling, flush filling, and underfilling after orthograde retreatment using MTA. METHODS: Two hundred fifty patients with 264 teeth diagnosed with previously treated root canals and apical periodontitis retreated in a private endodontic practice were included. All teeth received MTA obturation and the extent of the final filling level was measured in relation to the major apical foramen. After 6-month follow-ups, all nonhealing cases were treated surgically. After 24- to 72-month reviews, the effect of preoperative lesion size and the degree of MTA obturation level were assessed. Multiple linear regression and time-to-event analysis using Stata 17 software (StataCorp LLC, College Station, TX) were used to evaluate the data. RESULTS: Within the three cohorts, 99 out of 108 overfilled teeth (91.7%), 90 out of 103 flush fills (87.4%), and 10 out of 53 underfilled teeth (18.9%) healed and were successfully retreated without surgery at 48-months. When surgical outcomes were included, the combined healed proportion was 93.2%. Preoperative lesion size was found to be an important predictor for retreatment nonhealing. A 1-mm increase in lesion size at baseline resulted in an estimated 11% (95% CI 1.04, 1.18)-38% (95% CI 1.22, 1.58) increase in the risk of surgery. Compared to overfilling and flush filling, underfilling was associated with an approximately three-fold increase in requiring surgery and characterized by delayed healing. CONCLUSION: MTA obturation is a viable retreatment option for teeth with nonhealing endodontic treatment. MTA overfills or flush fillings do not adversely affect healing outcomes. However, MTA underfilling increases the chances for nonhealing and surgical intervention.

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STATEMENT OF PROBLEM: In endodontically treated maxillary first molars, post space preparations in the palatal roots can compromise the residual dentin thickness (RDT) and increase the risk of perforations or root fractures. This can be attributed to the direction of the buccopalatal curvature that cannot be viewed with conventional 2D imaging. PURPOSE: The purpose of this clinical study was to investigate the RDT of palatal roots following the placement of digital post analogs of different diameters positioned at various distances from the radiographic apex by using cone beam computed tomography (CBCT). MATERIAL AND METHODS: A total of 122 deidentified CBCT data sets containing both maxillary permanent first molars were randomly selected from a private radiology practice. Digital parallel-sided post analogs were superimposed onto the CBCT coronal images at distances of 3 mm, 4 mm, and 5 mm from the radiographic apex and at a depth equal to the height of the anatomic crown (1:1 crown/post ratio). Post analogs of 0.9 mm, 1.0 mm, and 1.14 mm in diameter were matched with safety zone analogs representing 1 mm of circumferential RDT. The minimum RDT for each analog was determined and grouped into 3 categories: RDT≤0 mm, 0 mm50.0%) had inadequate or no RDT. The depth of the post (P<.001) had a greater impact on RDT than the post diameter (P>.017). No similarities were found in the RDT between contralateral molars in 86.9% of the images. CONCLUSIONS: The risk of insufficient RDT (<1 mm) after the placement of parallel-sided posts in the palatal roots of maxillary first molars is minimized if the post is inserted to a depth equaling the height of the crown compared with 3, 4, and 5 mm from the radiographic apex. The RDT of the palatal root of a maxillary first molar is not a reliable predictor of the contralateral palatal root RDT in the same patient.

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This study aimed to compare the density of mineral trioxide aggregate (MTA) as a root canal filling material in the apical 5 mm of artificial root canals. Forty transparent acrylic blocks with 30-degree curved canals were instrumented and allocated into four compaction technique groups (n = 10): Lawaty (hand files); gutta-percha (GP) points; auger (nickel-titanium rotary files in reverse mode); and plugger technique. Filled canals were weighed after setting the MTA to calculate difference in mass. Two postoperative radiographs compared radiopacity by measuring luminance variations at 0.5 mm, 1 mm, 2 mm, 3 mm, 4 mm, and 5 mm from the root apex. Obturation time was measured using a digital chronometer. The significance level was set to p < 0.05. The plugger group had a lower mass. Relative luminance was significantly higher for the Lawaty group than the plugger group at all examined apical levels. The relative luminance of the auger and GP groups were significantly higher than the plugger group at depths between 0.5 mm and 2 mm. Relative luminance was highest for the Lawaty technique at all depths between 0.5 mm and 4 mm. The Lawaty technique group was associated with increased obturation time compared with pluggers. Compacting MTA in curved canals with the Lawaty technique has the highest mass and radiopacity but requires more time.

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INTRODUCTION: Separated endodontic instruments may adversely affect the outcome of endodontic treatment. The combination of ultrasonic techniques and dental operating microscopes appears to be effective in the removal of separated instruments compared with more randomized techniques. This study evaluated the roles of root canal curvature and separated instrument length on the time needed to loosen and retrieve the instrument fragments. METHODS: The retrieval procedures of 128 separated instruments referred to a private endodontic practice for retreatment by general practitioners were evaluated in patients who were monitored for a minimum of 6 months. Preoperative cone-beam computed tomographic images were used to measure separated instrument lengths in relation to the degrees of canal curvatures. Ultrasonic instruments were used in the initial phase to remove the tooth structure and to loosen the fractured instrument. In the second phase, ultrasonic instruments, wire loops, or XP Shapers (FKG Dentaire SA, La Chaux-de-Fonds, Switzerland) were used for fragment removal. The time periods for all procedures were recorded. Statistical analysis was completed applying log-normal regression, structural equation modeling, and linear regression using Stata Version 14.2 software (StataCorp LLC, College Station, TX). RESULTS: All separated instruments were successfully retrieved. Using the protocol in this study, 89.8% of the instruments were removed using ultrasonic instruments alone with a mean time of 221 seconds. The instrument removal time was dependent on both the instrument length and the root canal curvature. Additionally, preparation times were proportionately longer with increasing separated instrument lengths when the loop device was required. CONCLUSIONS: The preparation phase appears to have an important role in the retrieval of separated instruments. Preparation times for both non-loop and loop groups demonstrate that length and curvature are independent predictors of the log-transformed time. Generally, procedure times were extended with increasing file lengths and higher degrees of canal curvature.

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Apexification strategies in traumatised non-vital immature permanent teeth can promote root-end closure and continued root development. However, traumatic injuries may compromise the integrity of generative cells of the apical papilla responsible for root maturation. This report describes the long-term treatment outcome of mineral trioxide aggregate (MTA) apexification managed with late-term surgical intervention. A seven-year-old male reported with swelling and suppuration associated with a traumatised maxillary left central incisor (#21). After palliative treatment and MTA apexification procedures, the incisor demonstrated normal function during a 14.5-year period with radiographic evidence of atypical radicular elongation. Seventeen years after initial treatment, the patient presented with mid-plate buccal swelling and surgical treatment was completed involving root resection, biopsy of a spherical mineralised tissue specimen and placement of MTA root-end filling. Periapical healing and normal tooth function was evident at the 20-year review.

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The types of pulpal disease found in multirooted teeth may vary from one root canal to the next. Current endodontic treatment strategies allow for options such as regenerative endodontics, vital pulp therapy, or conventional root canal treatment depending on the disease status of the pulp in a specific root canal. A combination of procedures was used in the 3 teeth in this case series based on the assumed pulpal status in each canal. The follow-up ranged from 24-27 months, and in each case the healing response was satisfactory. This report illustrates the use of a combination of treatment procedures that can provide specific treatment benefits in various clinical situations.

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Vital pulp therapy (VPT) is devised to preserve and maintain vitality of pulpally involved teeth challenged by a variety of intraoral conditions. Notable progress has been made in this field due to a better understanding of pulp physiology, improved clinical protocols and advanced bioceramic materials paired with adhesive technology. With focused case selection, conservative VPT can provide reliable treatment options for permanent teeth diagnosed with normal pulps or reversible pulpitis.

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Mineral trioxide aggregate (MTA) has emerged as a reliable bioactive material with extended applications in endodontics that include the obturation of the root canal space. This article examines the literature supporting MTA as a canal filling material, suggests methods for its delivery and placement, and presents clinical cases that demonstrate its effectiveness in resolving apical periodontitis under a variety of circumstances. Case reports are presented documenting clinical outcomes after the application of MTA that include retreatment, obturation combined with root-end resection, apexification, internal resorption, dens in dente, and in conventional endodontic therapy. The review introduces clinicians to an alternative treatment strategy that might improve the healing outcomes for patients presenting with complex and challenging endodontic conditions.

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BACKGROUND: Pulp capping in carious teeth has been considered unpredictable and therefore contraindicated. A recently developed material, mineral trioxide aggregate (MTA), resists bacterial leakage and may provide protection for the pulp, allowing repair and continued pulp vitality in teeth when used in combination with a sealed restoration. METHODS: Forty patients aged 7 to 45 years accepted pulp-capping treatment when they received a diagnosis no more severe than reversible pulpitis after undergoing cold testing and radiographic examination. The primary author removed caries using a caries detector dye and sodium hypochlorite solution for hemostasis and placed MTA over the exposures and all surrounding dentin. The operator then restored the teeth provisionally with unbonded Clearfil Photocore (Kuraray Medical, Okayama, Japan). During a second visit, the operator restored the teeth with bonded composite after sensibility testing and confirmed MTA curing. At recall appointments, patients were evaluated for reparative dentin formation, pulpal calcification, continued normal root development and evidence of pathosis. RESULTS: Over an observation period of nine years, the authors followed 49 of 53 teeth and found that 97.96 percent had favorable outcomes on the basis of radiographic appearance, subjective symptoms and cold testing. All teeth in younger patients (15/15) that initially had open apexes showed completed root formation (apexogenesis). CONCLUSIONS: MTA can be a reliable pulp-capping material on direct carious exposures in permanent teeth when a two-visit treatment protocol is observed. PRACTICE IMPLICATIONS: Vital pulp therapy using MTA is a treatment option for teeth diagnosed with a condition no more severe than reversible pulpitis.

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