Asunto(s)
Picaduras de Arañas/diagnóstico , Niño , Humanos , Masculino , Picaduras de Arañas/complicaciones , ArañasRESUMEN
A 2-year-old girl with Crouzon's disease underwent three craniectomies. At age 4, she began a series of psychological tests to monitor her intellectual and academic functioning. Eight years after surgery, her intellectual functioning was comparable to that of her unaffected sister and far superior to that of her affected cousins, who were from similar home environments. Although the exact contributions of early identification and surgical intervention to the patient's intellectual and academic achievement could not be ascertained, these results suggest that some patients who receive early surgical treatment for Crouzon's disease may maintain a consistent rate of intellectual and academic development.
Asunto(s)
Desarrollo Infantil , Disostosis Craneofacial/cirugía , Inteligencia , Logro , Preescolar , Disostosis Craneofacial/genética , Disostosis Craneofacial/psicología , Evaluación Educacional , Femenino , Estudios de Seguimiento , Humanos , Pruebas de Inteligencia , Factores de TiempoAsunto(s)
Errores Innatos del Metabolismo de los Aminoácidos/complicaciones , Arginina/metabolismo , Coma/complicaciones , Electroencefalografía , Lisina/metabolismo , Ornitina/metabolismo , Errores Innatos del Metabolismo de los Aminoácidos/diagnóstico , Preescolar , Proteínas en la Dieta/administración & dosificación , Humanos , MasculinoRESUMEN
A 4-month-old infant was proven to have acute plumbism attributed to the ingestion of lead-containing Chinese herbal medicines. The analyses of 11 brands of Chinese herbal medicines by flameless atomic absorption spectrophotometry revealed that one of the medicines, Po Ying Tan, made by company A, had a mean lead content of 7.5 mg per unit dose; the other 10 brands had lower but still significant lead contents. In Chinese communities, these medicines are used very frequently, without prescription, for many minor ailments. This practice places a large number of individuals at risk for acute and chronic lead poisoning.
Asunto(s)
Intoxicación por Plomo/etiología , Magnoliopsida , Ácido Edético/uso terapéutico , Hong Kong , Humanos , Lactante , Plomo/análisis , Plomo/metabolismo , Intoxicación por Plomo/tratamiento farmacológico , Intoxicación por Plomo/metabolismo , Magnoliopsida/análisis , Masculino , Extractos Vegetales/efectos adversosAsunto(s)
Regulación de la Temperatura Corporal , Fenilcetonurias/fisiopatología , Adolescente , Regulación de la Temperatura Corporal/efectos de los fármacos , Preescolar , Femenino , Fiebre/etiología , Humanos , Ácido Hidroxiindolacético/orina , Lactante , Masculino , Consumo de Oxígeno , Fenoles/orina , Fenilalanina/sangre , Fenilalanina/uso terapéutico , Fenilcetonurias/sangre , Fenilcetonurias/tratamiento farmacológico , Fenilcetonurias/orina , Tiritona , Piel/irrigación sanguínea , Temperatura Cutánea , Sudoración , Vacunas Tifoides-Paratifoides/farmacologíaRESUMEN
Two siblings with argininosuccinic aciduria were studied by an interdisciplinary team. Considerable variability in the clinical expression of this disorder was observed in comparison with previously reported cases. Detection of the heterozygous state in the parents and in a fetal sibling was demonstrated by tissue assay for argininosuccinase activity. Mental retardation and neurologic deficits in the affected children were irreversible with dietotherapy but growth was progressive and the general course was relatively benign.