RESUMEN
Three copies of the X chromosome were identified in a 5-year-old mixed breed infertile bitch. One year after the cytogenetic examination, the bitch died due to gastritis hemorrhagica, an inflammation of the mucus coat of the stomach. Dental studies showed congenital lack of some premolar and molar teeth. Ovaries were of normal shape and size. Also, histologic sections of the ovaries revealed their normal structure, with two corpora lutea and primary follicles. Phenotypic effects of X trisomy are discussed.
Asunto(s)
Infertilidad Femenina/genética , Trisomía , Cromosoma X , Animales , Anodoncia/genética , Anodoncia/veterinaria , Bandeo Cromosómico , Arco Dental/anomalías , Perros , FemeninoRESUMEN
Patient aged 48 with the cyst of the cervical part of thoracic duct was described. Cyst appeared as the result of inflammation. Histopathological examination excluded the cystic lymphangioma.
Asunto(s)
Quiste Mediastínico/patología , Conducto Torácico/patología , Vértebras Cervicales/patología , Diagnóstico Diferencial , Humanos , Imagen por Resonancia Magnética , Masculino , Quiste Mediastínico/etiología , Quiste Mediastínico/cirugía , Persona de Mediana Edad , Conducto Torácico/cirugíaRESUMEN
The paper presents three cases of localised amyloidosis of the larynx. The study was focused on case histories, findings of larynx examination and method of treatment was discussed. Amyloidosis is a disease characterised by gathering of amyloid deposits in extracellular space. The amyloid fibres consist of different kinds of proteins which have the ability of forming laminae. This disease may be secondary to numerous general processes in which amyloid proteins forms. Etiopathogenesis of this disease has not been explained yet. In the following paper the latest theories and classification of amyloidosis are presented.
Asunto(s)
Amiloidosis/patología , Enfermedades de la Laringe/patología , Adulto , Anciano , Humanos , Masculino , Persona de Mediana EdadAsunto(s)
Carcinoma de Células Renales/diagnóstico , Neoplasias Renales/diagnóstico , Riñón/patología , Cavidad Nasal/patología , Neoplasias Nasales/secundario , Carcinoma de Células Renales/tratamiento farmacológico , Carcinoma de Células Renales/patología , Femenino , Hormonas/uso terapéutico , Humanos , Neoplasias Renales/tratamiento farmacológico , Neoplasias Renales/patología , Persona de Mediana Edad , Cavidad Nasal/cirugía , Metástasis de la Neoplasia , Neoplasias Nasales/tratamiento farmacológico , Neoplasias Nasales/cirugíaRESUMEN
Clinicomorphological analysis has been performed in Schoenlein-Henoch nephropathy. Various clinical symptoms are accompanied by morphological changes of variable type and severity. Electron microscopy is a major tool for evaluating these changes. It relatively frequently modifies the diagnosis made by light microscopy. It mainly concerns class I and VI changes (according to a grading system of the International Study Group of Kidney Diseases in Childhood). It was shown that late prognosis was largely determined by the type and severity of morphological changes. Varying severity of changes in individual glomeruli in the same specimen requires in each case a comparison of results obtained by electron microscopy with those obtained by light microscopy in semithin sections. In three children biopsy was repeated. Progression of morphological changes was found in one child. He developed renal failure. In one child morphological changes on first biopsy did not differ from those on second biopsy. Repeated biopsy was performed due to the presence of hypertension. In one child with persistent proteinuria repeated biopsy showed marked attenuation of morphological changes.
Asunto(s)
Vasculitis por IgA/patología , Enfermedades Renales/patología , Adolescente , Biopsia , Niño , Preescolar , Femenino , Humanos , Vasculitis por IgA/complicaciones , Enfermedades Renales/etiología , Glomérulos Renales/ultraestructura , Asa de la Nefrona/ultraestructura , Masculino , PronósticoRESUMEN
The results of the studies in five children with the syndrome of thin basement membranes have been discussed. A comparison of clinical data with the morphological ones shows that recognition of erythrocyturia or hematuria necessitates familial examinations and long-term follow-up. Final diagnosis of this syndrome may be made only by means of electron microscopy.
Asunto(s)
Membrana Basal/ultraestructura , Hematuria/etiología , Enfermedades Renales/complicaciones , Niño , Familia , Femenino , Humanos , Enfermedades Renales/patología , Glomérulos Renales/ultraestructura , Masculino , Proteinuria/etiologíaRESUMEN
Clinical and morphological examinations in 25 children with the diagnosis of focal segmental glomerulosclerosis (FSG) show that: 1. electron microscopy permits a detection of FSG in its early stage when light microscopy does not reveal any changes, and immunomorphological studies do not show deposits 2. in this stage small focal interstitial changes may be visible 3. ultrastructural studies reveal changes in case of nonspecific light microscopy i.e. suggesting mesangial glomerulonephritis 4. in doubtful cases it is useful to repeat biopsy.