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1.
Int J Med Educ ; 6: 166-71, 2015 Nov 22.
Artículo en Inglés | MEDLINE | ID: mdl-26590951

RESUMEN

OBJECTIVE: To identify faculty perceptions of simulation insertion in the undergraduate program, considering the advantages and challenges posed by this resource. METHODS: We conducted a qualitative study with intentional sampling according to pre-defined criteria, following a semi-structured outline regarding data saturation. We have interviewed 14 healthcare instructors from a teaching institution that employs simulation in its syllabi. RESULTS: The majority of the faculty interviewed considered the use of scenario, followed by debriefing, as an excellent teaching tool. However, the faculty also noted a number of difficulties, such as the workload necessary to assemble the scenario, the correlation between scenario goals and the competences of the program, the time spent with the simulation, and the ratio of students to faculty members. CONCLUSIONS: Faculties consider simulation an effective tool in the healthcare program and maintain that the main obstacle faced by them is the logistical demand.


Asunto(s)
Actitud , Educación Médica/métodos , Educación en Enfermería/métodos , Docentes , Entrenamiento Simulado , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad
2.
Nutr J ; 14: 19, 2015 Feb 19.
Artículo en Inglés | MEDLINE | ID: mdl-25886278

RESUMEN

BACKGROUND: Folate and vitamin B12 are essential nutrients, whose deficiencies are considerable public health problems worldwide, affecting all age groups. Low levels of these vitamins have been associated with high concentrations of homocysteine (Hcy) and can lead to health complications. Several genetic polymorphisms affect the metabolism of these vitamins. The aims of this study were to assess folate, vitamin B12 and homocysteine status in distinct Brazilian individuals after the initiation of folic acid fortification by Brazilian authorities and to investigate the effects of RFC1 A80G, GCPII C1561T and MTHFR C677T polymorphisms on folate, vitamin B12 and Hcy levels in these populations. METHODS: A total of 719 individuals including the elderly, children, as well as pregnant and lactating women were recruited from our health care center. Folate, vitamin B12 and Hcy levels were measured by conventional methods. Genotype analyses of RFC1 A80G, GCPII C1561T and MTHFR C677T polymorphisms were performed by PCR-RFLP. RESULTS: The overall prevalence of folate and vitamin B12 deficiencies were 0.3% and 4.9%, respectively. Folate deficiency was observed only in the elderly (0.4%) and pregnant women (0.3%), whereas vitamin B12 deficiency was observed mainly in pregnant women (7.9%) and the elderly (4.2%). Plasma Hcy concentrations were significantly higher in the elderly (33.6%). Pregnant women carrying the MTHFR 677TT genotype showed lower serum folate levels (p = 0.042) and higher Hcy levels (p = 0.003). RFC1 A80G and GCPII C1561T polymorphisms did not affect folate and Hcy levels in the study group. After a multivariate analysis, Hcy levels were predicted by variables such as folate, vitamin B12, gender, age and RFC1 A80G polymorphism, according to the groups studied. CONCLUSION: Our results suggest that folate deficiency is practically nonexistent in the post-folic acid fortification era in the subgroups evaluated. However, screening for vitamin B12 deficiency may be particularly relevant in our population, especially in the elderly.


Asunto(s)
Deficiencia de Ácido Fólico/epidemiología , Ácido Fólico/sangre , Homocisteína/sangre , Deficiencia de Vitamina B 12/epidemiología , Vitamina B 12/sangre , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Brasil/epidemiología , Brasil/etnología , Carboxipeptidasas/genética , Niño , Preescolar , Femenino , Deficiencia de Ácido Fólico/sangre , Deficiencia de Ácido Fólico/genética , Deficiencia de Ácido Fólico/metabolismo , Humanos , Lactante , Lactancia/sangre , Lactancia/genética , Masculino , Metilenotetrahidrofolato Reductasa (NADPH2)/genética , Persona de Mediana Edad , Reacción en Cadena de la Polimerasa , Polimorfismo de Longitud del Fragmento de Restricción , Embarazo/sangre , Embarazo/metabolismo , Prevalencia , Proteína Portadora de Folato Reducido/genética , Factores de Riesgo , Factores Sexuales , Deficiencia de Vitamina B 12/sangre , Deficiencia de Vitamina B 12/genética , Deficiencia de Vitamina B 12/metabolismo , Adulto Joven
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