RESUMEN
The authors evaluated the Kodak Ektachem Slides for total, "direct," conjugated, unconjugated, and albumin-bound ("delta") bilirubin. For various concentrations of control material, the precision (CV) within- and between-day ranged from 1.7 to 2.4% (2.8-6.6%) for total bilirubin, 0.8-4.2% (1.6-11.5%) for unconjugated bilirubin, and 1.6-9.5% (2.6-20.7%) for conjugated bilirubin. The Ektachem total and "direct" bilirubin assays demonstrated excellent correlation with the Jendrassik and Grof procedure; a 30% difference was observed, however, between absolute numbers with the two direct bilirubin methods. We found the measurement of true conjugated bilirubin by the Kodak Method to be superior to the measurement of "direct" bilirubin in following the response to treatment of various hepatic disorders manifested by extrahepatic and intrahepatic biliary obstruction.
Asunto(s)
Bilirrubina/sangre , Colestasis Intrahepática/sangre , Colestasis/sangre , Película para Rayos X , Fraccionamiento Químico , HumanosRESUMEN
A patient with angioimmunoblastic lymphadenopathy diagnosed on initial lymph node biopsy was found on rebiopsy two months later to have immunoblastic lymphoma as well. At presentation she had polyclonal hypergammaglobulinemia with polyclonal (kappa and lambda light chains) immunoblasts demonstrated by the immunoperoxidase stain. During the course of her illness, a monoclonal IgM kappa gammaglobulinemia developed, accompanied by monoclonal (kappa light chains only) immunoblasts demonstrated by the immunoperoxidase method. These findings were unique in that lymphomatous transformation and clinical deterioration are shown to be accompanied by a monoclonal evolution of immunoblasts. This constitutes further evidence for the heterogeneous nature of patients who have angioimmunoblastic lymphadenopathy and the malignant potential of this disease.
Asunto(s)
Linfadenopatía Inmunoblástica/inmunología , Linfoma/inmunología , Femenino , Humanos , Hipergammaglobulinemia/inmunología , Inmunoelectroforesis , Técnicas para Inmunoenzimas , Inmunoglobulina M/inmunología , Ganglios Linfáticos/inmunología , Ganglios Linfáticos/patología , Persona de Mediana EdadRESUMEN
The results of a study of 214 touch imprints of benign and malignant lymphoid disorders are presented. The diagnostic criteria, including the results of special stains, are described for both benign proliferative disorders and malignant lymphomas. Imprint cytology achieved an accuracy of 99% in diagnosing both benign and malignant conditions. Specific subtyping of malignant disorders was correctly made in 83% of non-Hodgkin's lymphomas and in 66% of Hodgkin's lymphomas. It is concluded that imprint cytology is a useful adjunct to the histopathologic diagnosis of lymphoid disease.
Asunto(s)
Enfermedad de Hodgkin/diagnóstico , Enfermedades Linfáticas/diagnóstico , Linfoma/diagnóstico , Citodiagnóstico , Diagnóstico Diferencial , Enfermedad Granulomatosa Crónica/diagnóstico , Humanos , Leucemia de Células Pilosas/diagnóstico , Linfadenitis/diagnóstico , Enfermedades Linfáticas/patología , Linfoma/patologíaRESUMEN
Symptomatic disease from Strongyloides stercoralis has been recognized for the first time in Trinidad. Five cases are reported, all showing clinical features suggestive of a sprue-like syndrome. Subtotal jejunal villous atrophy was seen in one case and partial villous atrophy in two. Three patients had laparotomies because of suspected partial intestinal obstruction. A sprue-like syndrome in certain Caribbean immigrants should arouse a suspicion of S. stercoralis.
Asunto(s)
Parasitosis Intestinales/diagnóstico , Obstrucción Intestinal/diagnóstico , Estrongiloidiasis/diagnóstico , Adulto , Enfermedad Celíaca/diagnóstico , Diagnóstico Diferencial , Femenino , Humanos , Parasitosis Intestinales/tratamiento farmacológico , Intestino Delgado/patología , Masculino , Persona de Mediana Edad , Estrongiloidiasis/tratamiento farmacológico , Tiabendazol/uso terapéuticoRESUMEN
Symptomatic diseases from Strongyloides stercoralis has been recognized for the first time in Trinidad. Five cases are reported, all showing clinical features suggestive of a sprue-like syndrome. Subtotal jejunal villous atrophy was seen in one case and partial villous atrophy in two. Three patients had laparotomies bacause of suspected partial intestinal obstruction. A sprue-like syndrome in certain Caribbean immigrants should arouse a suspicion of S. stercoralis (Summary)