RESUMEN
In the article the perspective directions of development of methodology of the analysis of risk in Russia with taking into account the last world achievements in this area and requirements to harmonization of a system for control of environment quality are considered. Main problem questions of the analysis of risk in relation to regulation of nature protection activity were emphasized to be related as well with insufficiency of legislative, standard and executive support for this direction of administrative activity as with the need of the solution of the methodical questions concerning new tendencies of justification and use of reference levels of chemicals, development of modern approaches to the specification of cancerogenic and not cancerogenic risks, including cumulative ones.