RESUMEN
The frequency of arthropathy was evaluated in 251 patients with clinical and serological diagnosis (specific IgM detection by enzyme immunoassay) of exanthematous disease. Arthropathy (arthralgia and/or arthritis) was more frequent in dengue fever (49%) and rubella (38.2%) cases than in human parvovirus (30%) and measles (28.1%) cases. Except for measles cases, joint complaints prevailed in adults (> or = 15 years of age) and this difference was significant. The higher frequency of arthropathy in adults was more evident in human parvovirus (75%), rubella (65%) and dengue fever (57.7%) cases than in measles cases (31%). Arthropathy was also more frequent in females for all rash diseases studied. The results of this study showed the high occurrence of joint complaints in the disease described here and the importance of laboratory confirmation for their differential diagnosis.
Asunto(s)
Exantema/diagnóstico , Artropatías/diagnóstico , Enfermedades Cutáneas Virales/diagnóstico , Adolescente , Adulto , Anciano , Anticuerpos Antivirales/sangre , Brasil/epidemiología , Niño , Preescolar , Exantema/epidemiología , Femenino , Humanos , Inmunoglobulina M/sangre , Incidencia , Lactante , Artropatías/epidemiología , Masculino , Persona de Mediana Edad , Estudios Seroepidemiológicos , Enfermedades Cutáneas Virales/epidemiologíaRESUMEN
From March 1994 to November 1995 24 cases of human parvovirus B19 infection were seen at the Infectious Diseases Department of the Hospital Universitário Antônio Pedro, Niterói-RJ. Serum samples for IgM detection (capture enzyme immunoassay) were positive from the 1st to the 27th day after the onset of the exathema. The classical features of erythema infectiosum (slapped cheecked syndrome) were observed in 8 (33.3%) cases all of them children. Eight patients (6 adults and 2 children) presented a symmetrical polyartropathy, seen more frequently in women. These results show that B19 infection diagnosis is difficult when the disease does not present the classical features and because of the frequent involvement of the joints this infection should be considered in the differential diagnosis of early rheumatoid arthritis.