RESUMEN

We explored a 61 year old woman with mild hirsutism. An adrenal tumor was found in the left adrenal, which was held responsible for the androgen secretion. The in vitro incubation of the tumor tissue showed an impaired 11 beta-hydroxylation of 11-deoxycortisol. This is a rare and unusual case of adrenal pathology showing that a deficiency in 11 beta-hydroxylase activity does not rule out the presence of an adrenocortical adenoma.

Asunto(s)

Adenoma/enzimología , Neoplasias de la Corteza Suprarrenal/enzimología , Hiperplasia Suprarrenal Congénita , Esteroide Hidroxilasas/deficiencia , Adenoma/cirugía , Neoplasias de la Corteza Suprarrenal/cirugía , Adrenalectomía , Andrógenos/sangre , Femenino , Humanos , Cetosteroides/biosíntesis , Persona de Mediana Edad