RESUMEN

Several groups have demonstrated that healthy individuals can present the t(14;18) translocation. In this report, the presence of the translocation was examined in healthy blood donors in Brazil, a country considered an ethnic melting pot. The translocation was detected by nested PCR in 227 peripheral blood samples from individuals with different ethnic backgrounds. The t(14;18) translocation was found in 45 of 85 White individuals (52.94%); in 57 of 72 Black individuals (79.17%); and in 68 of 70 individuals (97.14%) of Japanese-descent. In conclusion, the frequency of the t(14;18) translocation in the Brazilian population varies according to the ethnic background.

Asunto(s)

Cromosomas Humanos Par 14 , Cromosomas Humanos Par 18 , Linfoma Folicular/etnología , Linfoma Folicular/genética , Translocación Genética , Adolescente , Adulto , Anciano , Donantes de Sangre , Brasil/etnología , Etnicidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reacción en Cadena de la Polimerasa , Adulto Joven