RESUMEN
A 7-year-old boy was seen for severe abdominal pain, vomiting, and a 2.0-kg weight loss of 2 weeks duration. Stools were Hemoccult positive. Upper gastrointestinal (UGI) endoscopy showed multiple, raised red lesions in the duodenal bulb and descending duodenum. Although the patient did not have the typical cutaneous eruption, other findings such as acute onset of abdominal pain in a previously healthy boy, absence of infectious or surgical lesions, and more importantly endoscopic changes seen typically in the descending duodenum, led to the likely diagnosis of Henoch-Schönlein purpura (HSP). The patient was treated with prednisone and the duodenal lesions resolved. The diagnosis of HSP was confirmed 24 weeks after the initial symptom when he developed a palpable purpuric rash over both legs. Thirteen months following the initial symptoms and 6 months after the onset of rash, severe abdominal pain with epigastric tenderness recurred and stools were Hemoccult positive. UGI endoscopy showed multiple, raised red lesions in the descending duodenum as seen earlier. The patient was diagnosed with recurrent HSP. This presentation is atypical because of the abnormally long interval between the onset of abdominal pain and the appearance of the skin rash, and unique because of the endoscopically demonstrated recurrent gastrointestinal lesions.
Asunto(s)
Duodenitis/diagnóstico , Vasculitis por IgA/diagnóstico , Niño , Duodenitis/patología , Duodenoscopía , Humanos , Vasculitis por IgA/patología , Masculino , RecurrenciaAsunto(s)
Síndrome de Budd-Chiari/etiología , Colitis Ulcerosa/complicaciones , Adolescente , Atrofia/patología , Biopsia/métodos , Síndrome de Budd-Chiari/diagnóstico , Síndrome de Budd-Chiari/patología , Colitis Ulcerosa/diagnóstico , Colitis Ulcerosa/patología , Hemoglobinas/análisis , Venas Hepáticas/patología , Humanos , Hígado/irrigación sanguínea , Hígado/diagnóstico por imagen , Hígado/patología , Masculino , Tiempo de Tromboplastina Parcial , Tomografía Computarizada por Rayos XAsunto(s)
Tos/complicaciones , Mucosa Gástrica/lesiones , Hematemesis/etiología , Mucosa Gástrica/patología , Humanos , Lactante , Masculino , RecurrenciaRESUMEN
A 43-yr-old woman developed carcinoma of the ampulla of Vater 20 yr after being successfully treated for Hodgkin's disease with radiotherapy and chemotherapy. Conditions related to the chronic effect of radiation, such as narrowing and fibrosis of abdominal tissue, hampered her diagnosis and treatment. After a total pancreatectomy to remove the carcinoma, the patient recovered. However, 15 months later, she developed severe digestive disturbances, adrenal insufficiency, pulmonary emboli, and vasculitis. She died the next month of sepsis and adult respiratory distress syndrome. Although her complications probably were related to residual effects from therapy and surgery, she had no clinical evidence of tumor recurrence.
Asunto(s)
Adenocarcinoma Papilar/etiología , Ampolla Hepatopancreática , Neoplasias del Conducto Colédoco/etiología , Enfermedad de Hodgkin/terapia , Neoplasias Inducidas por Radiación/etiología , Adulto , Terapia Combinada , Femenino , Humanos , Radioterapia/efectos adversosRESUMEN
A 16-year-old male with profound developmental disability acutely developed retching, irritability, and abdominal distension. He had undergone a fundoplication and placement of a feeding gastrostomy 6 months earlier. A button gastrostomy tube was subsequently placed, but was noted to be missing from the stoma when the patient was awakened by his mother one morning. Within 48 hours he developed signs of abdominal obstruction. Abdominal radiography confirmed the presence of the gastrostomy button at the ileocecal valve. After a trial of decompression and medical management failed, the button was successfully removed endoscopically, resulting in prompt resolution of the obstruction. Gastrostomy buttons are a newer alternative to conventional catheters, but can become dislodged and migrate, as illustrated by this case. Refinements in the outer wing design may be needed.
Asunto(s)
Cuerpos Extraños/terapia , Gastrostomía/efectos adversos , Válvula Ileocecal , Obstrucción Intestinal/etiología , Adolescente , Colonoscopía , Cuerpos Extraños/complicaciones , Humanos , MasculinoAsunto(s)
Gastos en Salud , Seguro de Salud/economía , Cuidados a Largo Plazo , Medicaid , Medicare , Estados UnidosRESUMEN
A patient with plasma cell leukemia and myelofibrosis excreted free immunoglobulin light chains and an abnormal monoclonal immunoglobulin (Ig) A in her urine. The IgA that was present in serum and urine had a sedimentation coefficient of 4.0 S. The molecule was comprised of both heavy and light chains but was antigenically deficient compared to normal IgA. As excreted in the urine, the protein appeared to be a half-molecule of IgA, with a partial deletion in the heavy chain, probably involving part or all of the C-terminal domain.
Asunto(s)
Inmunoglobulina A/orina , Leucemia de Células Plasmáticas/inmunología , Femenino , Humanos , Cadenas alfa de Inmunoglobulina/orina , Cadenas lambda de Inmunoglobulina/orina , Leucemia de Células Plasmáticas/complicaciones , Leucemia de Células Plasmáticas/orina , Persona de Mediana Edad , Mielofibrosis Primaria/complicaciones , Mielofibrosis Primaria/inmunología , Mielofibrosis Primaria/orinaRESUMEN
Salmonella species have been detected in nine food varieties by use of fluorescent antibodies without false-positive or false-negative results. Test antisera were specially prepared, commercially available, conjugated polyvalent O globulin absorbed with cultures of Escherichia coli and Citrobacter freundii, and polyvalent phase II H globulin antibodies. Use of this technique permits a decrease of 24 hr in time normally required for Salmonella detection when compared with cultural Salmonella recovery methods.