RESUMEN

The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement.

Asunto(s)

Buddleja/química , Glucósidos/farmacología , Glicósidos/farmacología , Fenoles/farmacología , Protectores Solares/farmacología , Animales , Escherichia coli/efectos de la radiación , Femenino , Glucósidos/química , Glicósidos/química , Cobayas , Masculino , Estructura Molecular , Fenoles/química , Componentes Aéreos de las Plantas/química , Factores de Tiempo , Rayos Ultravioleta