RESUMEN
BACKGROUND: The purpose of the present study was to assess saliva reliability in diagnosis and monitoring type 2 diabetes instead of blood. METHODS: Blood and unstimulated whole saliva were collected from 300 type 2 diabetic subjects and 300 healthy controls in fasting. Then, the salivary flow rate was calculated. All parameters including glucose, urea, amylase, total protein, albumin, C-reactive protein (CRP), immunoglobulin A (IgA), potassium, calcium and chloride were assessed in the supernatant, using an autoanalyzer. Oral exam was conducted by a single examiner on full mouth excluding third molars. Statistical analysis was performed by the SPSS 20.0 version. RESULTS: Saliva screening showed that glucose, urea, amylase, total protein, potassium, calcium and chloride were significantly higher in patients compared to controls (p < 0.05). Whereas, the IgA level and salivary flow rate were significantly reduced in patients (p < 0.05). No significant difference was found in albumin and CRP levels (p > 0.05). There was a significant positive correlation between salivary and plasma glucose levels (r = 0.887, and r = 0.900, p < 0.001), as well as, salivary and blood urea (r = 0.586, and r = 0.688, p < 0.001) in patients and controls, respectively. CONCLUSIONS: From this study, saliva could be suggested as a useful diagnostic tool for type 2 diabetes.
Asunto(s)
Acidosis Tubular Renal/complicaciones , Enfermedad de Mikulicz/diagnóstico , Osteomalacia/complicaciones , Síndrome de Sjögren/complicaciones , Síndrome de Sjögren/diagnóstico , Acidosis Tubular Renal/diagnóstico , Adolescente , Diagnóstico Diferencial , Femenino , Humanos , Enfermedad de Mikulicz/etiología , Osteomalacia/diagnósticoAsunto(s)
Mielinólisis Pontino Central/diagnóstico , Enfermedad Crónica , Femenino , Humanos , Hiponatremia/complicaciones , Hiponatremia/diagnóstico por imagen , Imagen por Resonancia Magnética , Persona de Mediana Edad , Mielinólisis Pontino Central/diagnóstico por imagen , Mielinólisis Pontino Central/etiología , RadiografíaRESUMEN
The rheumatoid polyarthritis is the most frequent chronic polyarthritis. It affects essentially the woman between 40 and 60 years. Rheumatic subcutaneous nodules and tenosynovitis are usually associated with seropositive symptomatic rheumatoid polyarthritis. It is, however, rare that they constitute the essential clinical expression of the disease. In this case, it makes dispute another exceptional form of rheumatoid arthritis such as rheumatoid nodulosis. A 60-year-old woman was hospitalized for tumefaction of the dorsal face of the right hand evolving two months before. The clinical examination found subcutaneous nodules from which the exploration ended in rheumatoid nodules with tenosynovitis. The evolution after four years was favourable under corticosteroid therapy, methotrexate, and colchicine.