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1.
Rev Esp Enferm Dig ; 99(8): 440-5, 2007 Aug.
Artículo en Español | MEDLINE | ID: mdl-18020859

RESUMEN

OBJECTIVE: The study was to assess changes in the rectal mucosa and pouch in a series of patients with familial adenomatous polyposis (FAP) who underwent either subtotal colectomy and ileorectal anastomosis (IRA) or proctocolectomy and ileal pouch-anal anastomosis (IPAA), and to evaluate the suitability of the follow-up interval and postoperative treatment employed to prevent the development of cancer. METHOD: This study involved 28 patients with FAP who underwent IRA (n=20) or IPAA (n=8), and were followed endoscopically over a mean period of 7.47 years. The number and both macroscopic and histological features of polyps before and after surgery, the treatment, and complications were all analyzed. The suitability of the follow-up interval was assessed. RESULTS: None of the 26 patients who complied with follow-up developed rectal cancer. Two patients developed rectal cancer at 21 and 36 months after withdrawing from the protocol. Except in two cases in which surgery was indicated, patients who developed adenomas during follow-up were treated by endoscopic polypectomy. CONCLUSIONS: In our series, the failure to comply with follow-up examinations was associated with cancer development.


Asunto(s)
Poliposis Adenomatosa del Colon/cirugía , Reservorios Cólicos , Íleon/cirugía , Recto/cirugía , Adolescente , Adulto , Canal Anal/cirugía , Anastomosis Quirúrgica , Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , España
2.
Rev. esp. enferm. dig ; 99(8): 440-445, ago. 2007.
Artículo en Es | IBECS | ID: ibc-63247

RESUMEN

Objetivo: analizar la evolución de la mucosa rectal y del reservorioasí como idoneidad de los intervalos de seguimiento y deltratamiento realizado para evitar la aparición del cáncer, en unaserie de pacientes con poliposis adenomatosa familiar (PAF), intervenidos.Método: estudio prospectivo de 28 pacientes con PAF intervenidosmediante anastomosis íleo-rectal (20 pacientes) y anastomosisíleo-anal con reservorio (8 pacientes). A todos se les habíarealizado un control endoscópico dos veces al año y análisis delnúmero y características macroscópicas e histológicas de los póliposantes y después de la cirugía así como del tratamiento realizado,de sus complicaciones y de la adecuación del intervalo de seguimiento.El seguimiento medio fue de 6,47 años (DE = 4,59;rango = 0,72-16,75 años).Resultados: ninguno de los 26 pacientes que cumplimentaroncorrectamente el protocolo de seguimiento desarrolló cáncer.Sólo dos pacientes lo desarrollaron al 1,75 y los 3 años, respectivamentedel abandono del protocolo. Los pacientes que desarrollaronadenomas durante el seguimiento fueron tratados con éxitomediante polipectomía endoscópica, salvo en dos casos que se indicócirugía.Conclusiones: en nuestra serie, el incumplimiento de las revisionesha sido el factor que ha condicionado la aparición de cáncer


Objective: the study was to assess changes in the rectal mucosaand pouch in a series of patients with familial adenomatouspolyposis (FAP) who underwent either subtotal colectomy and ileorectalanastomosis (IRA) or proctocolectomy and ileal pouchanalanastomosis (IPAA), and to evaluate the suitability of the follow-up interval and postoperative treatment employed to preventthe development of cancer.Method: this study involved 28 patients with FAP who underwentIRA (n=20) or IPAA (n=8), and were followed endoscopicallyover a mean period of 7.47 years. The number and bothmacroscopic and histological features of polyps before and aftersurgery, the treatment, and complications were all analyzed. Thesuitability of the follow-up interval was assessed.Results: none of the 26 patients who complied with follow-updeveloped rectal cancer. Two patients developed rectal cancer at21 and 36 months after withdrawing from the protocol. Except intwo cases in which surgery was indicated, patients who developedadenomas during follow-up were treated by endoscopic polypectomy.Conclusions: in our series, the failure to comply with followupexaminations was associated with cancer development


Asunto(s)
Humanos , Poliposis Adenomatosa del Colon/cirugía , Neoplasias Colorrectales/prevención & control , Poliposis Adenomatosa del Colon/patología , Cuidados Posoperatorios/métodos , Protocolos Clínicos , Complicaciones Posoperatorias/prevención & control , Estudios Prospectivos , Mucosa Intestinal/patología , Anastomosis Quirúrgica
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