RESUMEN
Brimonidine is a third-generation alpha-2 adrenergic agonist and is classified as an ocular hypotensive agent. It is used for chronic glaucoma treatment by lowering intraocular pressure, crucial for preventing blindness. Brimonidine works by reducing aqueous humor production and increasing uveoscleral outflow. The improper use of brimonidine in children can result in severe adverse effects. If brimonidine eye drops are ingested orally, it can cause significant depression of the cardiorespiratory and central nervous systems. This is a case report of a 27-day-old neonate, who presented with central nervous system and respiratory depression after accidental ingestion of one drop of brimonidine tartrate ophthalmic solution. On arrival, he was having shallow breathing, a low Glasgow Coma Scale score, pinpoint pupils, and absent deep tendon reflexes. Gastric lavage was performed and supportive treatment was started. The patient showed gradual improvement and completely recovered within 48 hours.
RESUMEN
BACKGROUND: Anorexia nervosa, an eating disorder, is characterized by a distorted body image, intense fear of gaining weight, and self-imposed starvation. The aim of this study is to analyze type of information as well as its quality and reliability on YouTube about anorexia nervosa. Methodology: A cross-sectional observational study was conducted on 59 Youtube videos using anorexia nervosa-related keywords in June 2023. The characteristics of the YouTube videos, such as the language of the information, the time of upload, and the qualifications of the uploaders, were recorded. The content and quality of 59 videos were assessed using the Global Quality Score (GQS) and reliability grading systems. RESULTS: The videos accumulated a total of 256,602 likes, 5,644 dislikes, and 17,761 comments. Treatment-related content accounted for 81.36% of the videos, while descriptions of symptoms comprised 79.66%. Doctors contributed to 18.6% of the total uploads, making them the second-largest group of uploaders after the 'Other' category. The median reliability score for doctors is 4, the same as the hospital healthcare organization. This indicates that the perceived reliability of doctors as a source of information is as high as that of hospital healthcare organizations. CONCLUSIONS: In conclusion, this study highlights the importance of critically evaluating information on anorexia nervosa videos on YouTube. Despite variations in popularity, the overall quality and reliability remained consistent. Doctors were perceived as reliable sources of information, comparable to hospital healthcare organizations. Ensuring accurate and trustworthy content is crucial for supporting those affected by anorexia nervosa and promoting reliable information to the public.
RESUMEN
Coronavirus disease (COVID-19), caused by SARS-CoV-2, is a disease that has caused a global impact. COVID-19 is transmitted through airborne droplets, respiratory secretions, and direct contact. The pandemic has affected individuals of different ages, and studying the impact of COVID-19 on maternal and newborn outcomes is critical. In this review, we highlight the impact of COVID-19 infection in pregnancy and its repercussion in the maternal-fetal binomial. Physiological changes that occur during pregnancy have significant effects on the immune system, cardiopulmonary system, and coagulation, and these changes can result in an altered response to COVID-19 infection. The symptoms, risk factors, and maternal health consequences of COVID-19 were discussed. In addition, the impact of newborns born to mothers with COVID-19 was reviewed. Finally, placental changes and vertical transmission of COVID-19 during pregnancy were also discussed in this review.