RESUMEN
Article describes literature review of "atypical" osteomyelitis--osteonecrosis of facial bones among addicts to synthetic narcotics desomorphine and pervitin, different comorbidities, treatment strategy and prognosis were outlined
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Trastornos Relacionados con Anfetaminas/complicaciones , Osteonecrosis de los Maxilares Asociada a Difosfonatos/diagnóstico , Osteonecrosis de los Maxilares Asociada a Difosfonatos/terapia , Codeína/análogos & derivados , Consumidores de Drogas , Metanfetamina/efectos adversos , Dependencia de Morfina/complicaciones , Osteonecrosis de los Maxilares Asociada a Difosfonatos/etiología , Codeína/efectos adversos , Huesos Faciales/efectos de los fármacos , Huesos Faciales/patología , Humanos , Osteomielitis/inducido químicamente , Osteomielitis/diagnóstico , Osteomielitis/terapiaAsunto(s)
Trastornos Relacionados con Anfetaminas/patología , Codeína/análogos & derivados , Huesos Faciales/patología , Metanfetamina/toxicidad , Dependencia de Morfina/patología , Osteonecrosis/patología , Fósforo/toxicidad , Cráneo/patología , Trastornos Relacionados con Anfetaminas/complicaciones , Codeína/toxicidad , Consumidores de Drogas , Humanos , Dependencia de Morfina/complicaciones , Osteonecrosis/inducido químicamente , Osteonecrosis/cirugíaRESUMEN
Objective: To estimate the possibilities of using and systematizing computed tomographic findings in patients with toxic phosphorus necrosis of the jaw. Material and Methods: The investigation enrolled 87 patients diagnosed as having toxic phosphorus osteonecrosis. Radiation examination consisted of two stages: primary and repeated radiologic examinations in the postoperative period (final examination before hospital discharge). All the patients underwent skull X-ray and multislice computed tomography (MSCT). Results: Clinical and radiation examination revealed toxic phosphorus osteonecrosis of the maxilla and mandible in 29 (33%) cases. Osteonecrosis affected only the mandible in 40 (46%) cases and only the maxilla in 18 (21%) cases. In all the patients, computed tomography showed main trends in the X-ray semiotics of toxic phosphorus necrosis of the facial skeleton, such as periostitis; osteosclerosis; development a lesion having a "soap-bubble" appearance; nonspecific and inflammatory bone destruction. The bone, being destroyed, was replaced by pus; inflammatory granulations were absent; osteonecrosis occurred. These processes were characterized by the absence of an obvious demarcation zone along the edges of the process. Sequestration commonly occurred to form sinus tracts. The process involved the adjacent bones; there were reactive changes in the accessory sinuses. Conclusion: MSCT data are of highly informative value in evaluating the status of bone tissue and teeth and in detecting a concomitant abnormality in patients with osteonecrosis of the facial skeleton and may be used to plan surgical treatment for this category of patients.
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Codeína/análogos & derivados , Mandíbula , Maxilar , Tomografía Computarizada Multidetector/métodos , Osteonecrosis/diagnóstico , Fósforo/toxicidad , Adulto , Analgésicos Opioides/química , Analgésicos Opioides/toxicidad , Codeína/química , Codeína/toxicidad , Femenino , Humanos , Drogas Ilícitas/química , Drogas Ilícitas/toxicidad , Masculino , Mandíbula/diagnóstico por imagen , Mandíbula/patología , Maxilar/diagnóstico por imagen , Maxilar/patología , Osteonecrosis/inducido químicamente , Osteonecrosis/cirugía , Cuidados Preoperatorios/métodos , Reproducibilidad de los ResultadosRESUMEN
The study included 15 patients with purulent inflammatory diseases of maxillofacial area and 25 patients with facial bone necrosis induced by synthetic drugs. Pro- and anti-inflammatory cytokines levels in saliva and wound fluid were analyzed in two groups. The results proved cytokines to play important role in jaw necrosis induced by drugs containing red phosphorus.
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Citocinas/inmunología , Drogas Ilícitas/efectos adversos , Enfermedades Maxilomandibulares/inducido químicamente , Derivados de la Morfina/efectos adversos , Osteonecrosis/inducido químicamente , Adulto , Citocinas/análisis , Femenino , Humanos , Interleucina-10/análisis , Interleucina-10/inmunología , Enfermedades Maxilomandibulares/inmunología , Masculino , Persona de Mediana Edad , Derivados de la Morfina/administración & dosificación , Osteonecrosis/inmunología , Saliva/química , Saliva/inmunología , Factor de Crecimiento Transformador beta/análisis , Factor de Crecimiento Transformador beta/inmunología , Factor de Necrosis Tumoral alfa/análisis , Factor de Necrosis Tumoral alfa/inmunología , Adulto JovenRESUMEN
The article describes clinical and radiological classification of osteonecrosis of the mandible in patients with drug dependence, surgical options presented on the basis of classification proposed. Clinical case of simultaneous application of individual plate of nikelid titanium in patient with osteonecrosis of the mandible is presented.
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Placas Óseas , Enfermedades Mandibulares/clasificación , Enfermedades Mandibulares/cirugía , Níquel , Osteonecrosis/clasificación , Osteonecrosis/cirugía , Trastornos Relacionados con Sustancias/complicaciones , Titanio , Adulto , Humanos , Masculino , Enfermedades Mandibulares/complicaciones , Osteonecrosis/complicaciones , Tomografía Computarizada por Rayos XRESUMEN
OBJECTIVE: To elaborate a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction. MATERIAL AND METHODS: Ninety-two patients with drug addiction who had undergone orthopantomography, direct frontal X-ray of the skull, and multislice computed tomography, followed by multiplanar and three-dimensional imaging reconstruction were examined. One hundred thirty four X-ray films and 74 computed tomographic images were analyzed. RESULTS: The authors proposed a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction and elaborated recommendations for surgical interventions on the basis of the developed classification. CONCLUSION: The developed clinical and X-ray classification and recommendations for surgical interventions may be used to treat osteonecroses of various etiology.