RESUMEN

Crude extracts of Agave americana contain two utero-active compounds. One of these, tentatively named "Fraction B", has been purified to chromatographic homogeneity. Its pharmacological actions are similar to those of acetylcholine. However its chromatographic and electrophoretic mobilities are different. Some chemical properties of fraction B are compatible with the structure of an acyl derivative of choline different from acetylcholine

Asunto(s)

Ratas , Animales , Femenino , Extractos Vegetales/farmacología , Útero , Cromatografía en Capa Delgada , Extractos Vegetales/aislamiento & purificación , Ratas Endogámicas

Asunto(s)

Ratas , Animales , Femenino , Ácidos Nicotínicos/farmacología , Etanol/antagonistas & inhibidores , Piridoxina/farmacología , Cloruros/metabolismo , Combinación de Medicamentos , Ácido gamma-Aminobutírico/metabolismo , Ratas Endogámicas , Receptores de GABA-A/efectos de los fármacos , Receptores de GABA-A/metabolismo , Sueño , Transporte Biológico