RESUMEN
Post-exposure vaccination of bovines against rabies with three anti-rabies vaccines viz. BHK21 cell culture inactivated vaccine. "Raksharab", Vero cell culture vaccine and Semple's vaccine was studied with different schedules of vaccination. The mean RFFIT and ELISA titres of animals vaccinated with Raksharab and Vero cell culture vaccine reached a peak 95 days post-exposure (dpe). The animals vaccinated with Semple's vaccine showed maximum RFFIT and ELISA titres on 40 dpe and the titres were lower than those induced by tissue culture rabies vaccines. All the calves vaccinated with Raksharab and Vero cell culture vaccine were protected. One out of six calves vaccinated with Semple's vaccine died of rabies on 16 dpe. All the control animals died of rabies between 14 and 22 dpe. Raksharab schedule of vaccination on days 0, 4, 7, 14, 28 and 90 dpe was effective when compared with other vaccines with similar and different schedules. Tissue culture rabies vaccine is superior to nervous tissue vaccine in eliciting satisfactory immune response required to protect animals exposed to virulent rabies virus.
Asunto(s)
Enfermedades de los Bovinos/prevención & control , Vacunas Antirrábicas/administración & dosificación , Rabia/veterinaria , Vacunación/veterinaria , Animales , Anticuerpos Antivirales/sangre , Bovinos , Línea Celular , Chlorocebus aethiops , Cricetinae , Esquemas de Inmunización , Masculino , Rabia/prevención & control , Vacunas Antirrábicas/inmunología , Virus de la Rabia/inmunología , Células VeroRESUMEN
Forty otherwise healthy patients over 50 years of age with early, severe painful herpes zoster were randomly allocated to two groups for treatment. Twenty patients received prednisolone 40 mg daily with gradual reduction over a period of 4 weeks, whilst the other twenty patients received carbamazepine 100 mg four times daily. Thirteen of the twenty patients (65%) in the carbamazepine treated group developed post-herpetic neuralgia lasting up to 2 years, whilst only three of the twenty prednisolone treated patients (15%) had post-herpetic neuralgia lasting up to 6 months only. Thus the incidence and duration of post-herpetic neuralgia were considerably redudced in the prednisolone treated group. In neither group did disseminated zoster or other complications occur.
Asunto(s)
Carbamazepina/uso terapéutico , Herpes Zóster/complicaciones , Neuralgia/prevención & control , Prednisolona/uso terapéutico , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neuralgia/etiología , Factores de TiempoRESUMEN
A case of tuberculosis affecting the skin and nasal septum and 10 years later involving the hard palate causing perforation is reported.