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1.
Australas J Dermatol ; 41(2): 98-100, 2000 May.
Artículo en Inglés | MEDLINE | ID: mdl-10812703

RESUMEN

A 30-year-old man presented with numerous papules, nodules and inflamed cysts. The lesions were located all over the body, including the scalp, except the palms and soles. His mother and one sister had had similar but less extensive lesions. Histopathology of the biopsy specimens obtained from the anterior chest wall, axillae and the back region was consistent with steatocystoma multiplex (SM). A diagnosis of steatocystoma multiplex suppurativum was made. The inflamed lesions were treated with oral isotretinoin (1 mg/kg per daily) for 6 months. At the same time, cryotherapy was used for non-suppurating lesions smaller than 2 cm. When the patient was evaluated 6 months later, cosmetic results were good. No new lesions have appeared in the subsequent 12-month follow up.


Asunto(s)
Crioterapia , Quistes/tratamiento farmacológico , Isotretinoína/uso terapéutico , Queratolíticos/uso terapéutico , Enfermedades Cutáneas Papuloescamosas/tratamiento farmacológico , Administración Oral , Adulto , Biopsia , Terapia Combinada , Quistes/genética , Estética , Estudios de Seguimiento , Humanos , Isotretinoína/administración & dosificación , Queratolíticos/administración & dosificación , Masculino , Enfermedades Cutáneas Papuloescamosas/genética , Supuración
2.
J Eur Acad Dermatol Venereol ; 13(2): 113-7, 1999 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-10568490

RESUMEN

A large number of dermatoses associated with either morphea and psoriasis have been reported. However, to the best of our knowledge there is only one report in the literature about coexistence of morphea and psoriasis. Here we report a case of morphea and psoriasis that improved with acitretin treatment. The concomitant occurrence of these two dermatoses may be explained by immunological factors or trauma. We think that the improvement of the morphea lesions may be due to an immunomodulatory effect of the drug or a decrease in collagen production by dermal fibroblasts due to retinoic acid.


Asunto(s)
Acitretina/uso terapéutico , Queratolíticos/uso terapéutico , Psoriasis/tratamiento farmacológico , Esclerodermia Localizada/tratamiento farmacológico , Colágeno/análisis , Femenino , Humanos , Persona de Mediana Edad , Psoriasis/complicaciones , Psoriasis/patología , Esclerodermia Localizada/complicaciones , Esclerodermia Localizada/patología , Piel/patología
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