1.
Molecules
; 23(6)2018 Jun 14.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29904007
RESUMEN
(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno N-heterocycles and organometallic species are efficient and modular reactions to access these attractive scaffolds. An overview of our work concerning the cobalt-catalyzed arylation of iodo-substituted cyclic amines is presented.
Asunto(s)
Aminas/química , Cobalto/química , Catálisis , Estructura Molecular
2.
Org Lett
; 16(23): 6160-3, 2014 Dec 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-25401684
RESUMEN
Iron- and cobalt-catalyzed cross-couplings between iodo-azetidines, -pyrrolidines, -piperidines, and Grignard reagents are disclosed. The reaction is efficient, cheap, chemoselective and tolerates a large variety of (hetero)aryl Grignard reagents.